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• W3104560802 abstract "Given the various viral outbreaks in the 21st century, specifically the present pandemic situation arising from SARS-CoV-2 or the coronavirus, of unknown magnitude, there is an unmet clinical need to develop effective therapeutic and diagnostic strategies to combat this infectious disease worldwide. To develop precise anticoronavirus drugs and prophylactics, tissue engineering and biomaterial research strategies can serve as a suitable alternative to the conventional treatment options. Therefore, in this Review, we have highlighted various tissue engineering-based diagnostic systems for SARS-CoV-2 and suggested how these strategies involving organ-on-a-chip, organoids, 3D bioprinting, and advanced bioreactor models can be employed to develop in vitro human tissue models, for more efficient diagnosis, drug/vaccine development, and focusing on the need for patient-specific therapy. We believe that combining the basics of virology with tissue engineering techniques can help the researchers to understand the molecular mechanism underlying viral infection, which is critical for effective drug design. In addition, it can also serve to be a suitable platform for drug testing and delivery of small molecules that can lead to therapeutic tools in this dreaded pandemic situation. Additionally, we have also discussed the essential biomaterial properties which polarize the immune system, including dendritic cells and macrophages, toward their inflammatory phenotype, which can thus serve as a reference for exhibiting the role of biomaterial in influencing the adaptive immune response involving B and T lymphocytes to foster a regenerative tissue microenvironment. The situation arising from SARS-CoV-2 poses a challenge to scientists from almost all disciplines, and we feel that tissue engineers can thus provide new translational opportunities in this dreadful pandemic situation." @default.
• W3104560802 created "2020-11-23" @default.
• W3104560802 creator A5017091864 @default.
• W3104560802 creator A5020308795 @default.
• W3104560802 creator A5032369678 @default.
• W3104560802 creator A5076077990 @default.
• W3104560802 date "2020-11-16" @default.
• W3104560802 modified "2023-09-25" @default.
• W3104560802 title "Bioengineered <i>in Vitro</i> Tissue Models to Study SARS-CoV-2 Pathogenesis and Therapeutic Validation" @default.
• W3104560802 cites W1966238900 @default.
• W3104560802 cites W1967434989 @default.
• W3104560802 cites W1968782527 @default.
• W3104560802 cites W1970771505 @default.
• W3104560802 cites W1971704900 @default.
• W3104560802 cites W1971942652 @default.
• W3104560802 cites W1982559408 @default.
• W3104560802 cites W1989676021 @default.
• W3104560802 cites W1993700548 @default.
• W3104560802 cites W1996067969 @default.
• W3104560802 cites W1998352146 @default.
• W3104560802 cites W2000840731 @default.
• W3104560802 cites W2003953271 @default.
• W3104560802 cites W2004465286 @default.
• W3104560802 cites W2006231275 @default.
• W3104560802 cites W2015893533 @default.
• W3104560802 cites W2024102779 @default.
• W3104560802 cites W2032603645 @default.
• W3104560802 cites W2037282337 @default.
• W3104560802 cites W2040097914 @default.
• W3104560802 cites W2041180426 @default.
• W3104560802 cites W2042483765 @default.
• W3104560802 cites W2046153984 @default.
• W3104560802 cites W2046662624 @default.
• W3104560802 cites W2047471427 @default.
• W3104560802 cites W2048644480 @default.
• W3104560802 cites W2055797024 @default.
• W3104560802 cites W2061777515 @default.
• W3104560802 cites W2061801043 @default.
• W3104560802 cites W2063095964 @default.
• W3104560802 cites W2064492827 @default.
• W3104560802 cites W2065505772 @default.
• W3104560802 cites W2069836560 @default.
• W3104560802 cites W2070377914 @default.
• W3104560802 cites W2071859846 @default.
• W3104560802 cites W2072482781 @default.
• W3104560802 cites W2076044667 @default.
• W3104560802 cites W2076922024 @default.
• W3104560802 cites W2077251541 @default.
• W3104560802 cites W2080360768 @default.
• W3104560802 cites W2087250155 @default.
• W3104560802 cites W2090459898 @default.
• W3104560802 cites W2093756294 @default.
• W3104560802 cites W2098695079 @default.
• W3104560802 cites W2105076285 @default.
• W3104560802 cites W2107001989 @default.
• W3104560802 cites W2108771986 @default.
• W3104560802 cites W2114069528 @default.
• W3104560802 cites W2124838743 @default.
• W3104560802 cites W2132260239 @default.
• W3104560802 cites W2134005785 @default.
• W3104560802 cites W2143741861 @default.
• W3104560802 cites W2145795759 @default.
• W3104560802 cites W2155695407 @default.
• W3104560802 cites W2156862506 @default.
• W3104560802 cites W2161179961 @default.
• W3104560802 cites W2161684993 @default.
• W3104560802 cites W2161771297 @default.
• W3104560802 cites W2204617660 @default.
• W3104560802 cites W2235788736 @default.
• W3104560802 cites W2257005270 @default.
• W3104560802 cites W2301722455 @default.
• W3104560802 cites W2318443077 @default.
• W3104560802 cites W2342785428 @default.
• W3104560802 cites W2343832243 @default.
• W3104560802 cites W2415811952 @default.
• W3104560802 cites W2462162977 @default.
• W3104560802 cites W2554216581 @default.
• W3104560802 cites W2561827834 @default.
• W3104560802 cites W2609587333 @default.
• W3104560802 cites W2616699005 @default.
• W3104560802 cites W2620300384 @default.
• W3104560802 cites W2731132060 @default.
• W3104560802 cites W2757826601 @default.
• W3104560802 cites W2772587132 @default.
• W3104560802 cites W2776777030 @default.
• W3104560802 cites W2804856250 @default.
• W3104560802 cites W2807853324 @default.
• W3104560802 cites W2808978509 @default.
• W3104560802 cites W2809001631 @default.
• W3104560802 cites W2848847391 @default.
• W3104560802 cites W2892138690 @default.
• W3104560802 cites W2897603948 @default.
• W3104560802 cites W2900098650 @default.
• W3104560802 cites W2912276248 @default.
• W3104560802 cites W2915912019 @default.
• W3104560802 cites W2941905286 @default.
• W3104560802 cites W2946143686 @default.
• W3104560802 cites W2955957152 @default.

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