Matches in SemOpenAlex for { <https://semopenalex.org/work/W3104935789> ?p ?o ?g. }
- W3104935789 endingPage "653" @default.
- W3104935789 startingPage "645" @default.
- W3104935789 abstract "Background Treatment of patients with hemophilia has advanced over the past decades, but it is unknown whether this has resulted in a normal life expectancy in the Netherlands. Objective This observational cohort study aimed to assess all-cause and cause-specific mortality in patients with hemophilia in the Netherlands between 2001 and 2018 and to compare mortality and life expectancy with previous survival assessments from 1973 onward. Patients/methods All 1066 patients with hemophilia who participated in a nationwide survey in 2001 were followed until July 2018. Results Information on 1031 individuals (97%) was available, of whom 142 (14%) deceased during follow-up. Compared with the general Dutch male population, mortality of patients with hemophilia was still increased (standardized mortality ratio: 1.4, 95% confidence interval: 1.2–1.7). Intracranial bleeding and malignancies were the most common causes of death. Estimated median life expectancy of patients with hemophilia was 77 years, 6 years lower than the median life expectancy of the general Dutch male population (83 years). Over the past 45 years, death rates of patients with hemophilia have consistently decreased, approaching the survival experience of the general population. Over the past decades, mortality due to human immunodeficiency virus and hepatitis C virus infections has decreased, death due to intracranial hemorrhages has increased, and death due to ischemic heart disease has remained consistently low over time. Conclusions Survival in patients with hemophilia in the Netherlands has improved over time but is still lower than that of the general population." @default.
- W3104935789 created "2020-11-23" @default.
- W3104935789 creator A5002452498 @default.
- W3104935789 creator A5002870795 @default.
- W3104935789 creator A5003775399 @default.
- W3104935789 creator A5017437441 @default.
- W3104935789 creator A5025739874 @default.
- W3104935789 creator A5027063444 @default.
- W3104935789 creator A5031487360 @default.
- W3104935789 creator A5032770450 @default.
- W3104935789 creator A5036799045 @default.
- W3104935789 creator A5039403992 @default.
- W3104935789 creator A5044632676 @default.
- W3104935789 creator A5048888596 @default.
- W3104935789 creator A5051357297 @default.
- W3104935789 creator A5054098878 @default.
- W3104935789 creator A5055506605 @default.
- W3104935789 creator A5059760177 @default.
- W3104935789 creator A5066305508 @default.
- W3104935789 creator A5078770806 @default.
- W3104935789 creator A5078835349 @default.
- W3104935789 date "2021-03-01" @default.
- W3104935789 modified "2023-10-15" @default.
- W3104935789 title "Mortality, life expectancy, and causes of death of persons with hemophilia in the Netherlands 2001–2018" @default.
- W3104935789 cites W118483415 @default.
- W3104935789 cites W1575975406 @default.
- W3104935789 cites W1576917663 @default.
- W3104935789 cites W1759016357 @default.
- W3104935789 cites W1792170217 @default.
- W3104935789 cites W1879571322 @default.
- W3104935789 cites W1922525488 @default.
- W3104935789 cites W1968976167 @default.
- W3104935789 cites W1972227331 @default.
- W3104935789 cites W1978543860 @default.
- W3104935789 cites W1989059436 @default.
- W3104935789 cites W2010454173 @default.
- W3104935789 cites W2014269684 @default.
- W3104935789 cites W2017281907 @default.
- W3104935789 cites W2042453264 @default.
- W3104935789 cites W2044742476 @default.
- W3104935789 cites W2056974529 @default.
- W3104935789 cites W2073931583 @default.
- W3104935789 cites W2116345541 @default.
- W3104935789 cites W2124515032 @default.
- W3104935789 cites W2148400580 @default.
- W3104935789 cites W2153385311 @default.
- W3104935789 cites W2155259304 @default.
- W3104935789 cites W2282479894 @default.
- W3104935789 cites W2464367677 @default.
- W3104935789 cites W2605205627 @default.
- W3104935789 cites W2807179898 @default.
- W3104935789 cites W2907798910 @default.
- W3104935789 cites W2921837781 @default.
- W3104935789 cites W2965258952 @default.
- W3104935789 cites W2967535150 @default.
- W3104935789 cites W3021812684 @default.
- W3104935789 cites W3104935789 @default.
- W3104935789 cites W31080558 @default.
- W3104935789 cites W4250447582 @default.
- W3104935789 cites W4290684920 @default.
- W3104935789 cites W4290689669 @default.
- W3104935789 doi "https://doi.org/10.1111/jth.15182" @default.
- W3104935789 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7986360" @default.
- W3104935789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33217158" @default.
- W3104935789 hasPublicationYear "2021" @default.
- W3104935789 type Work @default.
- W3104935789 sameAs 3104935789 @default.
- W3104935789 citedByCount "42" @default.
- W3104935789 countsByYear W31049357892021 @default.
- W3104935789 countsByYear W31049357892022 @default.
- W3104935789 countsByYear W31049357892023 @default.
- W3104935789 crossrefType "journal-article" @default.
- W3104935789 hasAuthorship W3104935789A5002452498 @default.
- W3104935789 hasAuthorship W3104935789A5002870795 @default.
- W3104935789 hasAuthorship W3104935789A5003775399 @default.
- W3104935789 hasAuthorship W3104935789A5017437441 @default.
- W3104935789 hasAuthorship W3104935789A5025739874 @default.
- W3104935789 hasAuthorship W3104935789A5027063444 @default.
- W3104935789 hasAuthorship W3104935789A5031487360 @default.
- W3104935789 hasAuthorship W3104935789A5032770450 @default.
- W3104935789 hasAuthorship W3104935789A5036799045 @default.
- W3104935789 hasAuthorship W3104935789A5039403992 @default.
- W3104935789 hasAuthorship W3104935789A5044632676 @default.
- W3104935789 hasAuthorship W3104935789A5048888596 @default.
- W3104935789 hasAuthorship W3104935789A5051357297 @default.
- W3104935789 hasAuthorship W3104935789A5054098878 @default.
- W3104935789 hasAuthorship W3104935789A5055506605 @default.
- W3104935789 hasAuthorship W3104935789A5059760177 @default.
- W3104935789 hasAuthorship W3104935789A5066305508 @default.
- W3104935789 hasAuthorship W3104935789A5078770806 @default.
- W3104935789 hasAuthorship W3104935789A5078835349 @default.
- W3104935789 hasBestOaLocation W31049357891 @default.
- W3104935789 hasConcept C126322002 @default.
- W3104935789 hasConcept C126451531 @default.
- W3104935789 hasConcept C133925201 @default.
- W3104935789 hasConcept C179755657 @default.
- W3104935789 hasConcept C187212893 @default.
- W3104935789 hasConcept C201903717 @default.