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- W3105032502 abstract "Caring for the elderly nursing home patient has never been more clinically complex or administratively more troublesome. 1 Higashi T. Shekelle P.G. Solomon D.H. et al. The quality of pharmacologic care for vulnerable older patients. Ann Intern Med. 2004; 140: 714-720 Crossref PubMed Scopus (191) Google Scholar Patients carry with them a greater burden of disease with increasing frailty and vulnerability. 1 Higashi T. Shekelle P.G. Solomon D.H. et al. The quality of pharmacologic care for vulnerable older patients. Ann Intern Med. 2004; 140: 714-720 Crossref PubMed Scopus (191) Google Scholar More drugs are being used for more problems. Combination drug therapy (and by this we mean 2 or more drugs in the same pill or capsule) was not common or recommended even just a few years ago. Acceptable combinations for a long time were limited and they were represented by drugs such as hydrochlorothiazide/triamterene (Dyazide; GlaxoSmithKline, Research Triangle Park, NC) and carbidopa/levodopa (Sinemet; Merck & Co, Inc, Whitehouse Station, NJ). Other fixed combinations were generally unavailable because of the significant side effect profiles of individual agents and a relatively poor understanding of drug-drug interactions." @default.
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- W3105032502 date "2005-11-01" @default.
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- W3105032502 title "Combination Drug Therapy" @default.
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- W3105032502 doi "https://doi.org/10.1016/j.jamda.2005.04.013" @default.
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