FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3105221305> ?p ?o ?g. }

• W3105221305 endingPage "8" @default.
• W3105221305 startingPage "1" @default.
• W3105221305 abstract "We tested the hypothesis that ethanol consumption would aggravate the renal damage induced by cyclophosphamide (CYP). Male C57BL/6 J mice from control (n = 8) and CYP (n = 12) groups had free access to filtered water and standard rodent chow for 12 weeks. Then, 24 h before euthanasia mice received an intraperitoneal injection of saline or CYP (300 mg/kg). Mice from ethanol (n = 8) and CYP + ethanol (n = 12) groups had free access to increasing doses of ethanol for 12 weeks. Twenty-four hours before euthanasia, mice from ethanol and CYP + ethanol groups received an intraperitoneal injection of saline or CYP, respectively. Ethanol, CYP, or the association of both drugs augmented serum levels of creatinine and increased the levels of superoxide ([Formula: see text]) generation and thiobarbituric acid reactive substances in the renal cortex. Upregulation of Nox4 and increased activity of superoxide dismutase were detected in the renal cortex of mice treated with ethanol, CYP, or the combination of these drugs; however, these molecular alterations induced by CYP were not potentiated by ethanol consumption. Our findings revealed that chronic ethanol consumption had no potentiating effect on the nephrotoxic effects displayed by CYP. It is possible that the combination of these drugs showed no synergistic effect because they share the same molecular mechanisms of renal toxicity." @default.
• W3105221305 created "2020-11-23" @default.
• W3105221305 creator A5003264862 @default.
• W3105221305 creator A5016463511 @default.
• W3105221305 creator A5017192376 @default.
• W3105221305 creator A5035140285 @default.
• W3105221305 creator A5059874939 @default.
• W3105221305 creator A5065901855 @default.
• W3105221305 date "2020-11-11" @default.
• W3105221305 modified "2023-10-04" @default.
• W3105221305 title "Ethanol and cyclophosphamide induce similar nephrotoxic effects: possible role for Nox4 and superoxide" @default.
• W3105221305 cites W191793640 @default.
• W3105221305 cites W1944772401 @default.
• W3105221305 cites W1947082420 @default.
• W3105221305 cites W1964223796 @default.
• W3105221305 cites W1969456804 @default.
• W3105221305 cites W1970892849 @default.
• W3105221305 cites W1976153887 @default.
• W3105221305 cites W1997023449 @default.
• W3105221305 cites W1997854782 @default.
• W3105221305 cites W2001032180 @default.
• W3105221305 cites W2006370393 @default.
• W3105221305 cites W2023973783 @default.
• W3105221305 cites W2026181520 @default.
• W3105221305 cites W2030785785 @default.
• W3105221305 cites W2038411641 @default.
• W3105221305 cites W2039577899 @default.
• W3105221305 cites W2046616002 @default.
• W3105221305 cites W2054129051 @default.
• W3105221305 cites W2066248075 @default.
• W3105221305 cites W2093563591 @default.
• W3105221305 cites W2110614818 @default.
• W3105221305 cites W2117261670 @default.
• W3105221305 cites W2129899223 @default.
• W3105221305 cites W2138066827 @default.
• W3105221305 cites W2219200263 @default.
• W3105221305 cites W2286138735 @default.
• W3105221305 cites W2342852841 @default.
• W3105221305 cites W2464513471 @default.
• W3105221305 cites W2468879160 @default.
• W3105221305 cites W2510441948 @default.
• W3105221305 cites W2580447292 @default.
• W3105221305 cites W2733486550 @default.
• W3105221305 cites W2735042729 @default.
• W3105221305 cites W2737436877 @default.
• W3105221305 cites W2767726506 @default.
• W3105221305 cites W2803818979 @default.
• W3105221305 cites W2804648738 @default.
• W3105221305 cites W2904892687 @default.
• W3105221305 cites W2973624765 @default.
• W3105221305 cites W3004197632 @default.
• W3105221305 cites W3010293491 @default.
• W3105221305 cites W3035173256 @default.
• W3105221305 cites W772689564 @default.
• W3105221305 doi "https://doi.org/10.1139/cjpp-2020-0246" @default.
• W3105221305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33175570" @default.
• W3105221305 hasPublicationYear "2020" @default.
• W3105221305 type Work @default.
• W3105221305 sameAs 3105221305 @default.
• W3105221305 citedByCount "2" @default.
• W3105221305 countsByYear W31052213052021 @default.
• W3105221305 countsByYear W31052213052022 @default.
• W3105221305 crossrefType "journal-article" @default.
• W3105221305 hasAuthorship W3105221305A5003264862 @default.
• W3105221305 hasAuthorship W3105221305A5016463511 @default.
• W3105221305 hasAuthorship W3105221305A5017192376 @default.
• W3105221305 hasAuthorship W3105221305A5035140285 @default.
• W3105221305 hasAuthorship W3105221305A5059874939 @default.
• W3105221305 hasAuthorship W3105221305A5065901855 @default.
• W3105221305 hasConcept C126189478 @default.
• W3105221305 hasConcept C126322002 @default.
• W3105221305 hasConcept C134018914 @default.
• W3105221305 hasConcept C178790620 @default.
• W3105221305 hasConcept C181199279 @default.
• W3105221305 hasConcept C185592680 @default.
• W3105221305 hasConcept C2775838275 @default.
• W3105221305 hasConcept C2776151105 @default.
• W3105221305 hasConcept C2776694085 @default.
• W3105221305 hasConcept C2776755627 @default.
• W3105221305 hasConcept C2777397205 @default.
• W3105221305 hasConcept C2778577996 @default.
• W3105221305 hasConcept C2779719074 @default.
• W3105221305 hasConcept C2779765511 @default.
• W3105221305 hasConcept C2780091579 @default.
• W3105221305 hasConcept C2780159080 @default.
• W3105221305 hasConcept C2780161600 @default.
• W3105221305 hasConcept C2780795997 @default.
• W3105221305 hasConcept C29730261 @default.
• W3105221305 hasConcept C48349386 @default.
• W3105221305 hasConcept C55493867 @default.
• W3105221305 hasConcept C71924100 @default.
• W3105221305 hasConcept C98274493 @default.
• W3105221305 hasConceptScore W3105221305C126189478 @default.
• W3105221305 hasConceptScore W3105221305C126322002 @default.
• W3105221305 hasConceptScore W3105221305C134018914 @default.
• W3105221305 hasConceptScore W3105221305C178790620 @default.
• W3105221305 hasConceptScore W3105221305C181199279 @default.
• W3105221305 hasConceptScore W3105221305C185592680 @default.

• next