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• W3105222728 endingPage "8940" @default.
• W3105222728 startingPage "8908" @default.
• W3105222728 abstract "Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry–Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays." @default.
• W3105222728 created "2020-11-23" @default.
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• W3105222728 date "2016-12-02" @default.
• W3105222728 modified "2023-10-10" @default.
• W3105222728 title "Accelerated high-resolution photoacoustic tomography via compressed sensing" @default.
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• W3105222728 doi "https://doi.org/10.1088/1361-6560/61/24/8908" @default.
• W3105222728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27910824" @default.
• W3105222728 hasPublicationYear "2016" @default.
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