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• W3105332034 abstract "The size- and fluorescence-based sorting of micro- and nanoscale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here, we demonstrate a disposable microfluidic particle sorter that enables high-throughput, on-demand counting and binary sorting of submicron particles and cells using either fluorescence or an electrically based determination of particle size. Size-based sorting uses a resistive pulse sensor integrated on-chip, whereas fluorescence-based discrimination is achieved using on-the-fly optical image capture and analysis. Following detection and analysis, the individual particles are deflected using a pair of piezoelectric actuators, directing the particles into one of two desired output channels; the main flow goes into a third waste channel. The integrated system can achieve sorting fidelities of better than 98%, and the mechanism can successfully count and actuate, on demand, more than 60 000 particles/min." @default.
• W3105332034 created "2020-11-23" @default.
• W3105332034 creator A5005357337 @default.
• W3105332034 creator A5060265847 @default.
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• W3105332034 creator A5084811781 @default.
• W3105332034 date "2014-12-09" @default.
• W3105332034 modified "2023-10-18" @default.
• W3105332034 title "High-Speed Discrimination and Sorting of Submicron Particles Using a Microfluidic Device" @default.
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• W3105332034 doi "https://doi.org/10.1021/nl503783p" @default.
• W3105332034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25442878" @default.
• W3105332034 hasPublicationYear "2014" @default.
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