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- W3105364364 abstract "Abstract Intermediate filaments (IFs) perform a diverse set of well‐known functions including providing structural support for the cell and resistance to mechanical stress, yet recent evidence has revealed unexpected roles for IFs as stress response proteins. Previously, it was shown that the type III IF protein vimentin forms cage‐like structures around centrosome‐associated proteins destined for degradation, structures referred to as aggresomes, suggesting a role for vimentin in protein turnover. However, vimentin's function at the aggresome has remained largely understudied. In a recent report, vimentin was shown to be dispensable for aggresome formation, but played a critical role in protein turnover at the aggresome through localizing proteostasis‐related machineries, such as proteasomes, to the aggresome. Here, we review evidence for vimentin's function in proteostasis and highlight the organismal implications of these findings." @default.
- W3105364364 created "2020-11-23" @default.
- W3105364364 creator A5022023614 @default.
- W3105364364 creator A5058103066 @default.
- W3105364364 date "2020-11-01" @default.
- W3105364364 modified "2023-09-26" @default.
- W3105364364 title "Vimentin's side gig: Regulating cellular proteostasis in mammalian systems" @default.
- W3105364364 cites W1028927773 @default.
- W3105364364 cites W1507350206 @default.
- W3105364364 cites W1539441748 @default.
- W3105364364 cites W1544026316 @default.
- W3105364364 cites W1828557351 @default.
- W3105364364 cites W1829522570 @default.
- W3105364364 cites W1842994045 @default.
- W3105364364 cites W1941328510 @default.
- W3105364364 cites W1970108896 @default.
- W3105364364 cites W1978757317 @default.
- W3105364364 cites W1982461434 @default.
- W3105364364 cites W1982800819 @default.
- W3105364364 cites W1988866780 @default.
- W3105364364 cites W1989498124 @default.
- W3105364364 cites W1992120851 @default.
- W3105364364 cites W1995180698 @default.
- W3105364364 cites W2010089695 @default.
- W3105364364 cites W2010828130 @default.
- W3105364364 cites W2011299866 @default.
- W3105364364 cites W2013569307 @default.
- W3105364364 cites W2014752627 @default.
- W3105364364 cites W2016318902 @default.
- W3105364364 cites W2025348084 @default.
- W3105364364 cites W2031096972 @default.
- W3105364364 cites W2033787709 @default.
- W3105364364 cites W2034751980 @default.
- W3105364364 cites W2036654287 @default.
- W3105364364 cites W2051712110 @default.
- W3105364364 cites W2062371653 @default.
- W3105364364 cites W2064979804 @default.
- W3105364364 cites W2068213179 @default.
- W3105364364 cites W2070777173 @default.
- W3105364364 cites W2071696504 @default.
- W3105364364 cites W2080944141 @default.
- W3105364364 cites W2084156359 @default.
- W3105364364 cites W2090926709 @default.
- W3105364364 cites W2091261568 @default.
- W3105364364 cites W2092310066 @default.
- W3105364364 cites W2097712502 @default.
- W3105364364 cites W2099242521 @default.
- W3105364364 cites W2101027541 @default.
- W3105364364 cites W2101045265 @default.
- W3105364364 cites W2104230351 @default.
- W3105364364 cites W2111837223 @default.
- W3105364364 cites W2115373986 @default.
- W3105364364 cites W2115602689 @default.
- W3105364364 cites W2124177183 @default.
- W3105364364 cites W2130823501 @default.
- W3105364364 cites W2131612416 @default.
- W3105364364 cites W2132197680 @default.
- W3105364364 cites W2137209191 @default.
- W3105364364 cites W2141807385 @default.
- W3105364364 cites W2141977434 @default.
- W3105364364 cites W2144879614 @default.
- W3105364364 cites W2149761960 @default.
- W3105364364 cites W2153450659 @default.
- W3105364364 cites W2153591334 @default.
- W3105364364 cites W2160182641 @default.
- W3105364364 cites W2160481760 @default.
- W3105364364 cites W2163220944 @default.
- W3105364364 cites W2164065816 @default.
- W3105364364 cites W2170819844 @default.
- W3105364364 cites W2194882682 @default.
- W3105364364 cites W2216677116 @default.
- W3105364364 cites W2321195678 @default.
- W3105364364 cites W2464929337 @default.
- W3105364364 cites W2472899497 @default.
- W3105364364 cites W2504746053 @default.
- W3105364364 cites W2572887968 @default.
- W3105364364 cites W2611401896 @default.
- W3105364364 cites W2615829409 @default.
- W3105364364 cites W2619876526 @default.
- W3105364364 cites W2755492557 @default.
- W3105364364 cites W2757383676 @default.
- W3105364364 cites W2789933553 @default.
- W3105364364 cites W2889835308 @default.
- W3105364364 cites W2913151139 @default.
- W3105364364 cites W2952626583 @default.
- W3105364364 cites W2970253393 @default.
- W3105364364 cites W2981053448 @default.
- W3105364364 cites W3007679838 @default.
- W3105364364 cites W3015274209 @default.
- W3105364364 cites W3081704350 @default.
- W3105364364 doi "https://doi.org/10.1002/cm.21645" @default.
- W3105364364 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8216102" @default.
- W3105364364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33190414" @default.
- W3105364364 hasPublicationYear "2020" @default.
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