FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3105395511> ?p ?o ?g. }

• W3105395511 endingPage "518" @default.
• W3105395511 startingPage "505" @default.
• W3105395511 abstract "ABSTRACTIntroduction: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is well known as a novel member of the coronavirus family which caused a sudden outbreak of Coronavirus disease-2019 (COVID-19) in China that quickly developed into a global pandemic. No effective approaches are found as yet for the therapy and epidemiological control of this new virus. We searched the literature in PubMed, Scopus, Web of Knowledge, Google Scholar, and MeSH, for articles and abstracts describing SARS-CoV-2, COVID-19, pneumonia, clinical trials, drug, treatment, and medicine.Areas covered: The present study aimed to comprehensively overview the current literature on effective anti-SARS-CoV-2 drugs.Expert opinion: Since the beginning of this pandemic disease, many studies have been conducted to find effective drugs to prevent COVID-19, because there are no specific drugs for the treatment of this disease. Most of these drugs with the antiviral potential effect toward COVID-19 are already used as the treatment of other infectious diseases. Some drugs that show the promising therapeutic potential in the initial clinical studies include remdesivir as an inhibitor of RNA-dependent RNA polymerase and favipiravir as an inhibitor of virus replication. Currently, remdesivir received the FDA authorizes to use as an experimental drug for emergency use in COVID-19 patients.KEYWORDS: SARS-CoV-2covid-19pneumoniaclinical trialsdrug Article highlightsRemdesivir is an inhibitor of RNA-dependent RNA polymerase, approved by the FDA for emergency use in hospitalized patients with severe COVID-19.Favipiravir prevents the replication of the virus that is in the clinical trial phase II/III to investigate the safety and efficacy of that for COVID-19.The therapeutic antibodies can be a specific target for SARS-CoV-2, but it considers as a long-term solution.Along with the antiviral therapy, targeting the pathways that hijack via viral infection can consider as a promising way to overcoming SARS-CoV-2 infections.Drug repurposing can increase the chance of overcoming SARS-CoV-2 infections and offer a time- and cost-efficient alternative for making new therapies available to patients.Declaration of interestThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.Reviewer disclosuresPeer reviewers on this manuscript have no relevant financial or other relationships to disclose.Additional informationFundingThis paper was not funded." @default.
• W3105395511 created "2020-11-23" @default.
• W3105395511 creator A5000345369 @default.
• W3105395511 creator A5024188705 @default.
• W3105395511 creator A5030384476 @default.
• W3105395511 creator A5044232183 @default.
• W3105395511 creator A5082195284 @default.
• W3105395511 date "2020-12-06" @default.
• W3105395511 modified "2023-10-03" @default.
• W3105395511 title "An effective drug against COVID-19: reality or dream?" @default.
• W3105395511 cites W1868158647 @default.
• W3105395511 cites W1945955401 @default.
• W3105395511 cites W1945961678 @default.
• W3105395511 cites W1965411122 @default.
• W3105395511 cites W1965531501 @default.
• W3105395511 cites W1965936780 @default.
• W3105395511 cites W1995121548 @default.
• W3105395511 cites W2006434809 @default.
• W3105395511 cites W2018498519 @default.
• W3105395511 cites W2025170735 @default.
• W3105395511 cites W2033241349 @default.
• W3105395511 cites W2057439500 @default.
• W3105395511 cites W2065630216 @default.
• W3105395511 cites W2094875270 @default.
• W3105395511 cites W2095807050 @default.
• W3105395511 cites W2096238447 @default.
• W3105395511 cites W2097188280 @default.
• W3105395511 cites W2100967823 @default.
• W3105395511 cites W2104548316 @default.
• W3105395511 cites W2131262274 @default.
• W3105395511 cites W2132260239 @default.
• W3105395511 cites W2133701960 @default.
• W3105395511 cites W2139603860 @default.
• W3105395511 cites W2140338292 @default.
• W3105395511 cites W2148822770 @default.
• W3105395511 cites W2149185709 @default.
• W3105395511 cites W2150120685 @default.
• W3105395511 cites W2166867592 @default.
• W3105395511 cites W2167080692 @default.
• W3105395511 cites W2176471040 @default.
• W3105395511 cites W2285897784 @default.
• W3105395511 cites W2292700442 @default.
• W3105395511 cites W2520033800 @default.
• W3105395511 cites W2531018947 @default.
• W3105395511 cites W2561770637 @default.
• W3105395511 cites W2563411735 @default.
• W3105395511 cites W2581273760 @default.
• W3105395511 cites W2725497285 @default.
• W3105395511 cites W2739679816 @default.
• W3105395511 cites W2750464792 @default.
• W3105395511 cites W2753321278 @default.
• W3105395511 cites W2755284350 @default.
• W3105395511 cites W2766504265 @default.
• W3105395511 cites W2791347300 @default.
• W3105395511 cites W2798142780 @default.
• W3105395511 cites W2803051518 @default.
• W3105395511 cites W2912436263 @default.
• W3105395511 cites W2915009278 @default.
• W3105395511 cites W2969525890 @default.
• W3105395511 cites W2991491848 @default.
• W3105395511 cites W3000413850 @default.
• W3105395511 cites W3001118548 @default.
• W3105395511 cites W3003347489 @default.
• W3105395511 cites W3003951199 @default.
• W3105395511 cites W3005212621 @default.
• W3105395511 cites W3005679569 @default.
• W3105395511 cites W3007642524 @default.
• W3105395511 cites W3007940623 @default.
• W3105395511 cites W3008644093 @default.
• W3105395511 cites W3008954191 @default.
• W3105395511 cites W3009301311 @default.
• W3105395511 cites W3009912996 @default.
• W3105395511 cites W3010930696 @default.
• W3105395511 cites W3012078024 @default.
• W3105395511 cites W3012379316 @default.
• W3105395511 cites W3012588029 @default.
• W3105395511 cites W3013742505 @default.
• W3105395511 cites W3014962324 @default.
• W3105395511 cites W3016084006 @default.
• W3105395511 cites W3020695284 @default.
• W3105395511 cites W3023346879 @default.
• W3105395511 cites W3033737840 @default.
• W3105395511 cites W3034850094 @default.
• W3105395511 cites W3080175341 @default.
• W3105395511 cites W311927316 @default.
• W3105395511 cites W4206332605 @default.
• W3105395511 doi "https://doi.org/10.1080/17476348.2021.1854092" @default.
• W3105395511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33215942" @default.
• W3105395511 hasPublicationYear "2020" @default.
• W3105395511 type Work @default.
• W3105395511 sameAs 3105395511 @default.
• W3105395511 citedByCount "11" @default.
• W3105395511 countsByYear W31053955112021 @default.
• W3105395511 countsByYear W31053955112022 @default.
• W3105395511 countsByYear W31053955112023 @default.
• W3105395511 crossrefType "journal-article" @default.
• W3105395511 hasAuthorship W3105395511A5000345369 @default.
• W3105395511 hasAuthorship W3105395511A5024188705 @default.

• next