Matches in SemOpenAlex for { <https://semopenalex.org/work/W3105424830> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W3105424830 endingPage "39" @default.
- W3105424830 startingPage "35" @default.
- W3105424830 abstract "Staphylococcal superantigen-like 10 (SSL10) is one of the immunoglobulin G (IgG) binding proteins produced by Staphylococcus aureus (S. aureus). SSL10 is reported to bind to Fc region of human IgG and interfere its effector functions. As SSL10 shows no homology with other staphylococcal IgG binding proteins, the mechanism of interaction between SSL10 and IgG remains to clear. In this study we attempted to identify the regions of SSL10 that are responsible for binding to human IgG (hIgG) by analyzing the binding ability of chimeras between SSL10 and its paralog, SSL7. The chimeras that retained either β1-β3 or β10-β12 of SSL10 bound to immobilized hIgG. On the other hand, chimeras that lacked both of these regions did not show binding activity to hIgG. In far western analysis, biotinylated hIgG interacted with SSL10 and chimera that retained β1-β3 and β10-β12 of SSL10. Collectively, SSL10 has two responsible regions for binding to hIgG, one is located in N-terminal half of oligonucleotide/oligosaccharide-binding (OB)-fold domain and the other is in C-terminal half of β-grasp domain. These findings would contribute to understand the mechanism of immune evasion of S. aureus and also to develop vaccines and drugs against S. aureus." @default.
- W3105424830 created "2020-11-23" @default.
- W3105424830 creator A5006330319 @default.
- W3105424830 creator A5040769595 @default.
- W3105424830 creator A5042820658 @default.
- W3105424830 creator A5046587409 @default.
- W3105424830 creator A5072978347 @default.
- W3105424830 date "2018-01-01" @default.
- W3105424830 modified "2023-09-27" @default.
- W3105424830 title "Identification of the Regions Responsible for Binding to Human Immunoglobulin G in Staphylococcal Superantigen-Like Protein 10" @default.
- W3105424830 cites W1481634909 @default.
- W3105424830 cites W1534362605 @default.
- W3105424830 cites W1624721229 @default.
- W3105424830 cites W1896283776 @default.
- W3105424830 cites W1987513560 @default.
- W3105424830 cites W1998102324 @default.
- W3105424830 cites W2031317540 @default.
- W3105424830 cites W2035544684 @default.
- W3105424830 cites W2093638388 @default.
- W3105424830 cites W2104907221 @default.
- W3105424830 cites W2153570578 @default.
- W3105424830 cites W2154434872 @default.
- W3105424830 cites W2160906682 @default.
- W3105424830 cites W2218183054 @default.
- W3105424830 cites W2587566271 @default.
- W3105424830 cites W2791078585 @default.
- W3105424830 doi "https://doi.org/10.1248/bpbreports.1.2_35" @default.
- W3105424830 hasPublicationYear "2018" @default.
- W3105424830 type Work @default.
- W3105424830 sameAs 3105424830 @default.
- W3105424830 citedByCount "1" @default.
- W3105424830 countsByYear W31054248302022 @default.
- W3105424830 crossrefType "journal-article" @default.
- W3105424830 hasAuthorship W3105424830A5006330319 @default.
- W3105424830 hasAuthorship W3105424830A5040769595 @default.
- W3105424830 hasAuthorship W3105424830A5042820658 @default.
- W3105424830 hasAuthorship W3105424830A5046587409 @default.
- W3105424830 hasAuthorship W3105424830A5072978347 @default.
- W3105424830 hasBestOaLocation W31054248301 @default.
- W3105424830 hasConcept C104317684 @default.
- W3105424830 hasConcept C107824862 @default.
- W3105424830 hasConcept C125823703 @default.
- W3105424830 hasConcept C153911025 @default.
- W3105424830 hasConcept C159654299 @default.
- W3105424830 hasConcept C185592680 @default.
- W3105424830 hasConcept C203014093 @default.
- W3105424830 hasConcept C2779000548 @default.
- W3105424830 hasConcept C2779489039 @default.
- W3105424830 hasConcept C2780898057 @default.
- W3105424830 hasConcept C30278631 @default.
- W3105424830 hasConcept C36333154 @default.
- W3105424830 hasConcept C51639874 @default.
- W3105424830 hasConcept C523546767 @default.
- W3105424830 hasConcept C54355233 @default.
- W3105424830 hasConcept C55493867 @default.
- W3105424830 hasConcept C86803240 @default.
- W3105424830 hasConcept C95444343 @default.
- W3105424830 hasConceptScore W3105424830C104317684 @default.
- W3105424830 hasConceptScore W3105424830C107824862 @default.
- W3105424830 hasConceptScore W3105424830C125823703 @default.
- W3105424830 hasConceptScore W3105424830C153911025 @default.
- W3105424830 hasConceptScore W3105424830C159654299 @default.
- W3105424830 hasConceptScore W3105424830C185592680 @default.
- W3105424830 hasConceptScore W3105424830C203014093 @default.
- W3105424830 hasConceptScore W3105424830C2779000548 @default.
- W3105424830 hasConceptScore W3105424830C2779489039 @default.
- W3105424830 hasConceptScore W3105424830C2780898057 @default.
- W3105424830 hasConceptScore W3105424830C30278631 @default.
- W3105424830 hasConceptScore W3105424830C36333154 @default.
- W3105424830 hasConceptScore W3105424830C51639874 @default.
- W3105424830 hasConceptScore W3105424830C523546767 @default.
- W3105424830 hasConceptScore W3105424830C54355233 @default.
- W3105424830 hasConceptScore W3105424830C55493867 @default.
- W3105424830 hasConceptScore W3105424830C86803240 @default.
- W3105424830 hasConceptScore W3105424830C95444343 @default.
- W3105424830 hasIssue "2" @default.
- W3105424830 hasLocation W31054248301 @default.
- W3105424830 hasOpenAccess W3105424830 @default.
- W3105424830 hasPrimaryLocation W31054248301 @default.
- W3105424830 hasRelatedWork W1645995080 @default.
- W3105424830 hasRelatedWork W2050785019 @default.
- W3105424830 hasRelatedWork W2061985200 @default.
- W3105424830 hasRelatedWork W2093481758 @default.
- W3105424830 hasRelatedWork W2102704192 @default.
- W3105424830 hasRelatedWork W2146603724 @default.
- W3105424830 hasRelatedWork W2403562442 @default.
- W3105424830 hasRelatedWork W2945612861 @default.
- W3105424830 hasRelatedWork W4360989871 @default.
- W3105424830 hasRelatedWork W4383199237 @default.
- W3105424830 hasVolume "1" @default.
- W3105424830 isParatext "false" @default.
- W3105424830 isRetracted "false" @default.
- W3105424830 magId "3105424830" @default.
- W3105424830 workType "article" @default.