FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3105453424> ?p ?o ?g. }

• W3105453424 abstract "Based on epidemiologic and embryologic patterns, nonsyndromic orofacial clefts are commonly categorized into cleft lip with or without cleft palate (CL/P) and cleft palate alone (CP). While nearly forty risk genes have been identified for CL/P, few risk genes are known for CP. We used a new statistical method, PLACO, to identify genetic variants influencing risk of both CL/P and CP. In a combined multi-ethnic genome-wide study of 2,771 CL/P and 611 CP case-parent trios, we discovered 6 new loci of genetic overlap between CL/P and CP; 3 new loci between pairwise OFC subtypes; and 4 loci not previously implicated in OFCs. We replicated the shared genetic etiology of subtypes underlying CL/P, and further discovered loci of genetic overlap exhibiting etiologic differences. In summary, we found evidence for new genetic regions and confirmed some recognized OFC genes either exerting shared risk or with opposite effects on risk to OFC subtypes." @default.
• W3105453424 created "2020-11-23" @default.
• W3105453424 creator A5006226110 @default.
• W3105453424 creator A5025724901 @default.
• W3105453424 creator A5028435917 @default.
• W3105453424 creator A5034381623 @default.
• W3105453424 creator A5043806013 @default.
• W3105453424 creator A5058451144 @default.
• W3105453424 creator A5064886913 @default.
• W3105453424 creator A5077039955 @default.
• W3105453424 creator A5086448897 @default.
• W3105453424 date "2020-11-16" @default.
• W3105453424 modified "2023-09-25" @default.
• W3105453424 title "Pleiotropy method identifies genetic overlap between orofacial clefts at multiple loci from GWAS of multi-ethnictrios" @default.
• W3105453424 cites W1546520882 @default.
• W3105453424 cites W1911942601 @default.
• W3105453424 cites W1964690949 @default.
• W3105453424 cites W1968344288 @default.
• W3105453424 cites W1975171992 @default.
• W3105453424 cites W1976541655 @default.
• W3105453424 cites W1977928806 @default.
• W3105453424 cites W1980159022 @default.
• W3105453424 cites W1980887908 @default.
• W3105453424 cites W1992436001 @default.
• W3105453424 cites W1999943314 @default.
• W3105453424 cites W2009181345 @default.
• W3105453424 cites W2010453616 @default.
• W3105453424 cites W2014348387 @default.
• W3105453424 cites W2040734821 @default.
• W3105453424 cites W2057983634 @default.
• W3105453424 cites W2060683299 @default.
• W3105453424 cites W2076834372 @default.
• W3105453424 cites W2088287802 @default.
• W3105453424 cites W2099085143 @default.
• W3105453424 cites W2103030121 @default.
• W3105453424 cites W2113280212 @default.
• W3105453424 cites W2131036795 @default.
• W3105453424 cites W2140126911 @default.
• W3105453424 cites W2150656559 @default.
• W3105453424 cites W2163013660 @default.
• W3105453424 cites W2322931078 @default.
• W3105453424 cites W2335824872 @default.
• W3105453424 cites W2375782756 @default.
• W3105453424 cites W2510973425 @default.
• W3105453424 cites W2559709990 @default.
• W3105453424 cites W2566174779 @default.
• W3105453424 cites W2570434836 @default.
• W3105453424 cites W2586637063 @default.
• W3105453424 cites W2596694838 @default.
• W3105453424 cites W2607726870 @default.
• W3105453424 cites W2730537115 @default.
• W3105453424 cites W2755420712 @default.
• W3105453424 cites W2761519020 @default.
• W3105453424 cites W2765284830 @default.
• W3105453424 cites W2766556645 @default.
• W3105453424 cites W2770092353 @default.
• W3105453424 cites W2789861852 @default.
• W3105453424 cites W2796296864 @default.
• W3105453424 cites W2801693550 @default.
• W3105453424 cites W2900255713 @default.
• W3105453424 cites W2906199739 @default.
• W3105453424 cites W2956009122 @default.
• W3105453424 cites W2979115455 @default.
• W3105453424 cites W2979330907 @default.
• W3105453424 cites W2993459087 @default.
• W3105453424 cites W3016234209 @default.
• W3105453424 cites W3048277788 @default.
• W3105453424 cites W4235012347 @default.
• W3105453424 doi "https://doi.org/10.1101/2020.11.13.20231654" @default.
• W3105453424 hasPublicationYear "2020" @default.
• W3105453424 type Work @default.
• W3105453424 sameAs 3105453424 @default.
• W3105453424 citedByCount "0" @default.
• W3105453424 crossrefType "posted-content" @default.
• W3105453424 hasAuthorship W3105453424A5006226110 @default.
• W3105453424 hasAuthorship W3105453424A5025724901 @default.
• W3105453424 hasAuthorship W3105453424A5028435917 @default.
• W3105453424 hasAuthorship W3105453424A5034381623 @default.
• W3105453424 hasAuthorship W3105453424A5043806013 @default.
• W3105453424 hasAuthorship W3105453424A5058451144 @default.
• W3105453424 hasAuthorship W3105453424A5064886913 @default.
• W3105453424 hasAuthorship W3105453424A5077039955 @default.
• W3105453424 hasAuthorship W3105453424A5086448897 @default.
• W3105453424 hasBestOaLocation W31054534241 @default.
• W3105453424 hasConcept C104317684 @default.
• W3105453424 hasConcept C106208931 @default.
• W3105453424 hasConcept C126322002 @default.
• W3105453424 hasConcept C127716648 @default.
• W3105453424 hasConcept C135763542 @default.
• W3105453424 hasConcept C137627325 @default.
• W3105453424 hasConcept C153209595 @default.
• W3105453424 hasConcept C26207810 @default.
• W3105453424 hasConcept C54355233 @default.
• W3105453424 hasConcept C69991583 @default.
• W3105453424 hasConcept C71924100 @default.
• W3105453424 hasConcept C86803240 @default.
• W3105453424 hasConceptScore W3105453424C104317684 @default.
• W3105453424 hasConceptScore W3105453424C106208931 @default.
• W3105453424 hasConceptScore W3105453424C126322002 @default.
• W3105453424 hasConceptScore W3105453424C127716648 @default.

• next