Matches in SemOpenAlex for { <https://semopenalex.org/work/W310562816> ?p ?o ?g. }
- W310562816 endingPage "37" @default.
- W310562816 startingPage "1" @default.
- W310562816 abstract "Eukaryotic antimicrobial peptides (AMPs) first became a research focus in the middle decades of the twentieth century with the description of cecropins from moths and magainins from frogs. Since then, the number of reported AMPs has burgeoned to over 2000 with representatives in virtually all eukaryotic organisms. The availability of databases of AMPs has facilitated phylogenetic analyses, which have shown that the origins of β-defensins are traceable to an ancestral gene over half a billion years old, indicating the evolutionarily ancient nature of AMPs. An emerging theme from research on AMPs is their multifunctional nature, which we review here for β-defensins, and show that these peptides play roles in wound healing and modulation of both the innate and adaptive immune systems via the dual ability to promote and suppress the proinflammatory response to microbial infection." @default.
- W310562816 created "2016-06-24" @default.
- W310562816 date "2013-02-20" @default.
- W310562816 modified "2023-10-11" @default.
- W310562816 title "Antimicrobial Peptides: Their History, Evolution, and Functional Promiscuity" @default.
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