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- W3106115411 abstract "This chapter discusses the data on stress protein expression in Duchenne's muscular dystrophy and establishes comparisons with other myopathies, including polymyositis-dermatomyositis and mitochondrial myopathies. A number of myopathies, and Duchenne s muscular dystrophy in particular, display a variety of pathological processes suggestive of oxidative stress which could potentially lead to stress-related gene activation. The induction of heat shock protein 90 and ubiquitin in regenerating fibers appears to result from a selective regulation linked to features distinct from the disease process. Myogenesis as a differentiation process is regulated by various factors, including hormones and regulatory kinases. The inflammatory myopathies are a heterogeneous group of disorders comprising a number of entities which display symptoms of connective tissue diseases as well as characteristic immunological alterations. Mitochondrial myopathies, which give rise to a large group of clinical syndromes, are associated with mutations in the mitochondrial or nuclear genome affecting mitochondrial function." @default.
- W3106115411 created "2020-11-23" @default.
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- W3106115411 date "2020-11-25" @default.
- W3106115411 modified "2023-10-14" @default.
- W3106115411 title "Heat Shock Proteins in Duchenne Muscular Dystrophy and Other Muscular Diseases" @default.
- W3106115411 cites W4205090231 @default.
- W3106115411 doi "https://doi.org/10.1201/9781003067474-31" @default.
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