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• W3106570435 endingPage "8907" @default.
• W3106570435 startingPage "8907" @default.
• W3106570435 abstract "Asthma is a chronic inflammatory airway disease characterized by variable airflow obstruction in response to a wide range of exogenous stimuli. The airway epithelium is the first line of defense and plays an important role in initiating host defense and controlling immune responses. Indeed, increasing evidence indicates a range of abnormalities in various aspects of epithelial barrier function in asthma. A central part of this impairment is a disruption of the airway epithelial layer, allowing inhaled substances to pass more easily into the submucosa where they may interact with immune cells. Furthermore, many of the identified susceptibility genes for asthma are expressed in the airway epithelium. This review focuses on the biology of the airway epithelium in health and its pathobiology in asthma. We will specifically discuss external triggers such as allergens, viruses and alarmins and the effect of type 2 inflammatory responses on airway epithelial function in asthma. We will also discuss epigenetic mechanisms responding to external stimuli on the level of transcriptional and posttranscriptional regulation of gene expression, as well the airway epithelium as a potential treatment target in asthma." @default.
• W3106570435 created "2020-12-07" @default.
• W3106570435 creator A5005888467 @default.
• W3106570435 creator A5058700181 @default.
• W3106570435 creator A5083004478 @default.
• W3106570435 date "2020-11-24" @default.
• W3106570435 modified "2023-10-16" @default.
• W3106570435 title "The Airway Epithelium—A Central Player in Asthma Pathogenesis" @default.
• W3106570435 cites W1497986985 @default.
• W3106570435 cites W1504820480 @default.
• W3106570435 cites W1508974651 @default.
• W3106570435 cites W1510752733 @default.
• W3106570435 cites W1581327608 @default.
• W3106570435 cites W1592394199 @default.
• W3106570435 cites W1608289457 @default.
• W3106570435 cites W1625157530 @default.
• W3106570435 cites W1747499909 @default.
• W3106570435 cites W1819034630 @default.
• W3106570435 cites W1823764983 @default.
• W3106570435 cites W1839043230 @default.
• W3106570435 cites W1870393279 @default.
• W3106570435 cites W1876168846 @default.
• W3106570435 cites W1885649436 @default.
• W3106570435 cites W1920585820 @default.
• W3106570435 cites W1948717027 @default.
• W3106570435 cites W1964779747 @default.
• W3106570435 cites W1966218896 @default.
• W3106570435 cites W1969669892 @default.
• W3106570435 cites W1970574050 @default.
• W3106570435 cites W1973844632 @default.
• W3106570435 cites W1975075371 @default.
• W3106570435 cites W1975438745 @default.
• W3106570435 cites W1976569808 @default.
• W3106570435 cites W1976639879 @default.
• W3106570435 cites W1976907020 @default.
• W3106570435 cites W1978315083 @default.
• W3106570435 cites W1979780797 @default.
• W3106570435 cites W1980185618 @default.
• W3106570435 cites W1981699875 @default.
• W3106570435 cites W1981782394 @default.
• W3106570435 cites W1987118400 @default.
• W3106570435 cites W1988337204 @default.
• W3106570435 cites W1991656827 @default.
• W3106570435 cites W1993545609 @default.
• W3106570435 cites W1996058483 @default.
• W3106570435 cites W1996426153 @default.
• W3106570435 cites W1996955331 @default.
• W3106570435 cites W1998057092 @default.
• W3106570435 cites W2000103257 @default.
• W3106570435 cites W2001220620 @default.
• W3106570435 cites W2002892444 @default.
• W3106570435 cites W2003835480 @default.
• W3106570435 cites W2004490702 @default.
• W3106570435 cites W2005503891 @default.
• W3106570435 cites W2007736853 @default.
• W3106570435 cites W2008599922 @default.
• W3106570435 cites W2008763832 @default.
• W3106570435 cites W2011811265 @default.
• W3106570435 cites W2011998167 @default.
• W3106570435 cites W2012107292 @default.
• W3106570435 cites W2012992792 @default.
• W3106570435 cites W2015891257 @default.
• W3106570435 cites W2016258379 @default.
• W3106570435 cites W2021701428 @default.
• W3106570435 cites W2023685287 @default.
• W3106570435 cites W2023751898 @default.
• W3106570435 cites W2024301198 @default.
• W3106570435 cites W2025502983 @default.
• W3106570435 cites W2025662587 @default.
• W3106570435 cites W2026005412 @default.
• W3106570435 cites W2033294817 @default.
• W3106570435 cites W2034000631 @default.
• W3106570435 cites W2034697578 @default.
• W3106570435 cites W2035509260 @default.
• W3106570435 cites W2036163316 @default.
• W3106570435 cites W2039478605 @default.
• W3106570435 cites W2040973547 @default.
• W3106570435 cites W2041319760 @default.
• W3106570435 cites W2041550275 @default.
• W3106570435 cites W2043365196 @default.
• W3106570435 cites W2043551932 @default.
• W3106570435 cites W2043864886 @default.
• W3106570435 cites W2043943442 @default.
• W3106570435 cites W2046017757 @default.
• W3106570435 cites W2046879461 @default.
• W3106570435 cites W2048852807 @default.
• W3106570435 cites W2050130418 @default.
• W3106570435 cites W2051008458 @default.
• W3106570435 cites W2052439664 @default.
• W3106570435 cites W2055172715 @default.
• W3106570435 cites W2057450814 @default.
• W3106570435 cites W2061435251 @default.
• W3106570435 cites W2061847435 @default.
• W3106570435 cites W2062721883 @default.
• W3106570435 cites W2063379758 @default.
• W3106570435 cites W2063801679 @default.
• W3106570435 cites W2065445260 @default.
• W3106570435 cites W2067324660 @default.

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