Matches in SemOpenAlex for { <https://semopenalex.org/work/W3106908788> ?p ?o ?g. }
- W3106908788 endingPage "319" @default.
- W3106908788 startingPage "306" @default.
- W3106908788 abstract "The prevalence of obesity is increasing and progressively influencing physician-patient interactions. While there is a sizable amount of data demonstrating that obesity is a state of low-grade inflammation, to our knowledge, there is no single review summarizing its effects on hematologic parameters and thrombotic risk. We performed a literature search which largely surfaced observational studies, with a few systematic reviews and meta-analyses of these studies. We took care to review the mechanisms driving an inflammatory state and obesity's effect on white blood cells, red blood cells, platelets, and thrombotic risk. There is an observed relative, and sometimes absolute leukocytosis driven by this inflammatory state. Obesity is also associated with increased platelet counts and an increased risk for venous thromboembolism (VTE). Lastly, the association between obesity, iron deficiency (ID), and red blood cell counts may be present but remains uncertain. Recognizing the above associations may provide clinicians with reassurance regarding otherwise unexplained hematologic abnormalities in obese individuals. We hope this review will prompt future studies to further understand the underlying mechanisms driving these abnormalities and identify modifiable risk factors and potential therapeutic targets to prevent the development of probable obesity-associated conditions with significant morbidity and mortality, such as ID and VTE." @default.
- W3106908788 created "2020-12-07" @default.
- W3106908788 creator A5069151961 @default.
- W3106908788 creator A5079149345 @default.
- W3106908788 date "2020-12-13" @default.
- W3106908788 modified "2023-10-05" @default.
- W3106908788 title "The hematologic consequences of obesity" @default.
- W3106908788 cites W1524184093 @default.
- W3106908788 cites W1557693024 @default.
- W3106908788 cites W1588096497 @default.
- W3106908788 cites W1590967073 @default.
- W3106908788 cites W1771540296 @default.
- W3106908788 cites W1847387808 @default.
- W3106908788 cites W1851314291 @default.
- W3106908788 cites W190052799 @default.
- W3106908788 cites W1916220362 @default.
- W3106908788 cites W1919006336 @default.
- W3106908788 cites W1940858263 @default.
- W3106908788 cites W1951212149 @default.
- W3106908788 cites W1966336914 @default.
- W3106908788 cites W1967270772 @default.
- W3106908788 cites W1970859623 @default.
- W3106908788 cites W1971720175 @default.
- W3106908788 cites W1973483953 @default.
- W3106908788 cites W1976844022 @default.
- W3106908788 cites W1981718716 @default.
- W3106908788 cites W1982667003 @default.
- W3106908788 cites W1984004980 @default.
- W3106908788 cites W1984554913 @default.
- W3106908788 cites W1986970658 @default.
- W3106908788 cites W1989986631 @default.
- W3106908788 cites W1990506334 @default.
- W3106908788 cites W1991079474 @default.
- W3106908788 cites W1993358626 @default.
- W3106908788 cites W1993465503 @default.
- W3106908788 cites W1993800499 @default.
- W3106908788 cites W1995257650 @default.
- W3106908788 cites W1996273959 @default.
- W3106908788 cites W1997083960 @default.
- W3106908788 cites W2000530357 @default.
- W3106908788 cites W2001497857 @default.
- W3106908788 cites W2003895206 @default.
- W3106908788 cites W2006666326 @default.
- W3106908788 cites W2008869160 @default.
- W3106908788 cites W2016085094 @default.
- W3106908788 cites W2018804515 @default.
- W3106908788 cites W2021026995 @default.
- W3106908788 cites W2023731005 @default.
- W3106908788 cites W2025342289 @default.
- W3106908788 cites W2025517143 @default.
- W3106908788 cites W2026535985 @default.
- W3106908788 cites W2027502028 @default.
- W3106908788 cites W2030889739 @default.
- W3106908788 cites W2032825348 @default.
- W3106908788 cites W2033307460 @default.
- W3106908788 cites W2033538734 @default.
- W3106908788 cites W2034067398 @default.
- W3106908788 cites W2034357937 @default.
- W3106908788 cites W2035010389 @default.
- W3106908788 cites W2036089443 @default.
- W3106908788 cites W2043410520 @default.
- W3106908788 cites W2043646682 @default.
- W3106908788 cites W2045786717 @default.
- W3106908788 cites W2046226151 @default.
- W3106908788 cites W2046392948 @default.
- W3106908788 cites W2046933962 @default.
- W3106908788 cites W2049912996 @default.
- W3106908788 cites W2052766584 @default.
- W3106908788 cites W2053244168 @default.
- W3106908788 cites W2058199781 @default.
- W3106908788 cites W2058294329 @default.
- W3106908788 cites W2058414104 @default.
- W3106908788 cites W2059080581 @default.
- W3106908788 cites W2060899732 @default.
- W3106908788 cites W2061747711 @default.
- W3106908788 cites W2062178434 @default.
- W3106908788 cites W2063379611 @default.
- W3106908788 cites W2065201220 @default.
- W3106908788 cites W2065489856 @default.
- W3106908788 cites W2066160102 @default.
- W3106908788 cites W2067086317 @default.
- W3106908788 cites W2069759393 @default.
- W3106908788 cites W2070097356 @default.
- W3106908788 cites W2070200806 @default.
- W3106908788 cites W2071176238 @default.
- W3106908788 cites W2073008030 @default.
- W3106908788 cites W2073271820 @default.
- W3106908788 cites W2076099382 @default.
- W3106908788 cites W2076506432 @default.
- W3106908788 cites W2076633494 @default.
- W3106908788 cites W2076828888 @default.
- W3106908788 cites W2076947383 @default.
- W3106908788 cites W2078719918 @default.
- W3106908788 cites W2083592407 @default.
- W3106908788 cites W2084622089 @default.
- W3106908788 cites W2087625202 @default.
- W3106908788 cites W2088475546 @default.
- W3106908788 cites W2097260668 @default.