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- W3106952207 endingPage "9229" @default.
- W3106952207 startingPage "9229" @default.
- W3106952207 abstract "Endocrine disruptors (EDCs) can display estrogenic and androgenic effects, and their exposure has been linked to increased cancer risk. EDCs have been shown to directly affect cancer cell regulation and progression, but their influence on tumour microenvironment is still not completely elucidated. In this context, the signalling hub protein RACK1 (Receptor for Activated C Kinase 1) could represent a nexus between cancer and the immune system due to its roles in cancer progression and innate immune activation. Since RACK1 is a relevant EDCs target that responds to steroid-active compounds, it could be considered a molecular bridge between the endocrine-regulated tumour microenvironment and the innate immune system. We provide an analysis of immunomodulatory and cancer-promoting effects of different EDCs in shaping tumour microenvironment, with a final focus on the scaffold protein RACK1 as a pivotal molecular player due to its dual role in immune and cancer contexts." @default.
- W3106952207 created "2020-12-07" @default.
- W3106952207 creator A5028584376 @default.
- W3106952207 creator A5048975636 @default.
- W3106952207 creator A5055857436 @default.
- W3106952207 creator A5082724673 @default.
- W3106952207 date "2020-12-03" @default.
- W3106952207 modified "2023-10-05" @default.
- W3106952207 title "Endocrine-Disrupting Chemicals’ (EDCs) Effects on Tumour Microenvironment and Cancer Progression: Emerging Contribution of RACK1" @default.
- W3106952207 cites W1486741682 @default.
- W3106952207 cites W1546043964 @default.
- W3106952207 cites W1563347308 @default.
- W3106952207 cites W1564770936 @default.
- W3106952207 cites W1789164482 @default.
- W3106952207 cites W1846622755 @default.
- W3106952207 cites W1927679233 @default.
- W3106952207 cites W1934666423 @default.
- W3106952207 cites W1952500907 @default.
- W3106952207 cites W1964305994 @default.
- W3106952207 cites W1965141524 @default.
- W3106952207 cites W1968200608 @default.
- W3106952207 cites W1968640856 @default.
- W3106952207 cites W1968786809 @default.
- W3106952207 cites W1968922109 @default.
- W3106952207 cites W1969057487 @default.
- W3106952207 cites W1972208841 @default.
- W3106952207 cites W1972268723 @default.
- W3106952207 cites W1972825083 @default.
- W3106952207 cites W1977789206 @default.
- W3106952207 cites W1979704965 @default.
- W3106952207 cites W1980224211 @default.
- W3106952207 cites W1981388238 @default.
- W3106952207 cites W1981641775 @default.
- W3106952207 cites W1982714712 @default.
- W3106952207 cites W1990514940 @default.
- W3106952207 cites W1990783176 @default.
- W3106952207 cites W1990924578 @default.
- W3106952207 cites W1991714532 @default.
- W3106952207 cites W1993793397 @default.
- W3106952207 cites W1994048261 @default.
- W3106952207 cites W1994447535 @default.
- W3106952207 cites W1996714719 @default.
- W3106952207 cites W1997474221 @default.
- W3106952207 cites W1998110092 @default.
- W3106952207 cites W1999374666 @default.
- W3106952207 cites W1999468766 @default.
- W3106952207 cites W1999981983 @default.
- W3106952207 cites W2001077154 @default.
- W3106952207 cites W2005421886 @default.
- W3106952207 cites W2006104250 @default.
- W3106952207 cites W2008314858 @default.
- W3106952207 cites W2012644882 @default.
- W3106952207 cites W2012692174 @default.
- W3106952207 cites W2014811828 @default.
- W3106952207 cites W2016983859 @default.
- W3106952207 cites W2017343742 @default.
- W3106952207 cites W2017783643 @default.
- W3106952207 cites W2020299393 @default.
- W3106952207 cites W2020338693 @default.
- W3106952207 cites W2020781087 @default.
- W3106952207 cites W2021415192 @default.
- W3106952207 cites W2021954624 @default.
- W3106952207 cites W2022274575 @default.
- W3106952207 cites W2022376938 @default.
- W3106952207 cites W2022802363 @default.
- W3106952207 cites W2025340798 @default.
- W3106952207 cites W2026037366 @default.
- W3106952207 cites W2028958360 @default.
- W3106952207 cites W2030279830 @default.
- W3106952207 cites W2036486456 @default.
- W3106952207 cites W2036768705 @default.
- W3106952207 cites W2041280565 @default.
- W3106952207 cites W2044755379 @default.
- W3106952207 cites W2045495339 @default.
- W3106952207 cites W2048655519 @default.
- W3106952207 cites W2055218883 @default.
- W3106952207 cites W2055442682 @default.
- W3106952207 cites W2058297968 @default.
- W3106952207 cites W2060895562 @default.
- W3106952207 cites W2064787811 @default.
- W3106952207 cites W2067347793 @default.
- W3106952207 cites W2068630231 @default.
- W3106952207 cites W2070250286 @default.
- W3106952207 cites W2071501137 @default.
- W3106952207 cites W2071675304 @default.
- W3106952207 cites W2075261412 @default.
- W3106952207 cites W2075605442 @default.
- W3106952207 cites W2076910098 @default.
- W3106952207 cites W2078305858 @default.
- W3106952207 cites W2081061928 @default.
- W3106952207 cites W2081335476 @default.
- W3106952207 cites W2082743261 @default.
- W3106952207 cites W2083030818 @default.
- W3106952207 cites W2085002181 @default.
- W3106952207 cites W2085300637 @default.
- W3106952207 cites W2087181963 @default.
- W3106952207 cites W2087540265 @default.
- W3106952207 cites W2087683721 @default.