Matches in SemOpenAlex for { <https://semopenalex.org/work/W3107023904> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W3107023904 abstract "BACKGROUND:Sulphated saccharides, primarily sucralfate, have previously been indicatedfor the treatment of gastric and duodenal ulcers. In radio-labelled form, sucralfatehas also been used as a diagnostic agent for the imaging of gastrointestinalmucosa, since the substance binds selectively to ulcerated areas in the stomachand upper small intestine. It has been found that sucralfate exerts an antiinflammatoryeffect when applied topically to the skin and to mucosal surfaces,and that sucralfate exerts a beneficial effect on wounds when applied topically onepithelial surfaces outside the digestive tract. Accordingly, the present studyrelates to the use of sucralfate for the preparation of a medication for topicalapplication over the skin or to any nongastrointestinal surface. Although theevidence is not yet conclusive the clinical evidence tends to support the antiinflammatoryeffect and wound healing effect of sucralfate.OBJECTIVES OF THE STUDY:•To compare the efficacy of topical sucralfate with that of a control group using•conventional dressings, in the healing of diabetic ulcers in terms of:Number of days needed for healing•To study the healing properties of sucralfate in management ofnongastrointestinal wounds•Rate of reduction in mean ulcer surface area•To assess the effect of topical sucralfate on bacterial load by comparing theculture and sensitivity of wound swabs before and after application ofsucralfateMETHODOLOGY:This was a comparative study conducted at Tirunelveli Medical CollegeHospital,Tirunelveli.Total of 100 patients were studied. They were separated into2 groups through computerized randomization. Patients in Control group weretreated with conventional dressing and patients in Study group were treated withsucralfate dressing and watched for the wound size reduction.RESULTS:The study group patients showed higher reduction in wound size of about40.87%as against 15.63% of the control group with P value < 0.001.CONCLUSION:Topical application of sucralfate once daily significantly increasesincidence of wound healing and reduce the time required for healing in diabetic ulcers." @default.
- W3107023904 created "2020-12-07" @default.
- W3107023904 creator A5086042166 @default.
- W3107023904 date "2016-01-01" @default.
- W3107023904 modified "2023-09-27" @default.
- W3107023904 title "A clinical study of comparision between efficacy of topical sucralfate and conventional dressing in the managment of diabetic ulcer in Tirunelveli Medical College" @default.
- W3107023904 hasPublicationYear "2016" @default.
- W3107023904 type Work @default.
- W3107023904 sameAs 3107023904 @default.
- W3107023904 citedByCount "0" @default.
- W3107023904 crossrefType "dissertation" @default.
- W3107023904 hasAuthorship W3107023904A5086042166 @default.
- W3107023904 hasConcept C126322002 @default.
- W3107023904 hasConcept C134018914 @default.
- W3107023904 hasConcept C2776246392 @default.
- W3107023904 hasConcept C2777858829 @default.
- W3107023904 hasConcept C2910357528 @default.
- W3107023904 hasConcept C555293320 @default.
- W3107023904 hasConcept C71924100 @default.
- W3107023904 hasConcept C90924648 @default.
- W3107023904 hasConceptScore W3107023904C126322002 @default.
- W3107023904 hasConceptScore W3107023904C134018914 @default.
- W3107023904 hasConceptScore W3107023904C2776246392 @default.
- W3107023904 hasConceptScore W3107023904C2777858829 @default.
- W3107023904 hasConceptScore W3107023904C2910357528 @default.
- W3107023904 hasConceptScore W3107023904C555293320 @default.
- W3107023904 hasConceptScore W3107023904C71924100 @default.
- W3107023904 hasConceptScore W3107023904C90924648 @default.
- W3107023904 hasLocation W31070239041 @default.
- W3107023904 hasOpenAccess W3107023904 @default.
- W3107023904 hasPrimaryLocation W31070239041 @default.
- W3107023904 hasRelatedWork W191999177 @default.
- W3107023904 hasRelatedWork W1974370907 @default.
- W3107023904 hasRelatedWork W1975204726 @default.
- W3107023904 hasRelatedWork W1986699372 @default.
- W3107023904 hasRelatedWork W2048857747 @default.
- W3107023904 hasRelatedWork W2100498047 @default.
- W3107023904 hasRelatedWork W2128786917 @default.
- W3107023904 hasRelatedWork W2215872768 @default.
- W3107023904 hasRelatedWork W2416465000 @default.
- W3107023904 hasRelatedWork W2432836573 @default.
- W3107023904 hasRelatedWork W2467527705 @default.
- W3107023904 hasRelatedWork W2536576090 @default.
- W3107023904 hasRelatedWork W2914228305 @default.
- W3107023904 hasRelatedWork W2974482203 @default.
- W3107023904 hasRelatedWork W2989759467 @default.
- W3107023904 hasRelatedWork W3017515949 @default.
- W3107023904 hasRelatedWork W3100071504 @default.
- W3107023904 hasRelatedWork W3198968147 @default.
- W3107023904 hasRelatedWork W206311060 @default.
- W3107023904 hasRelatedWork W3082619608 @default.
- W3107023904 isParatext "false" @default.
- W3107023904 isRetracted "false" @default.
- W3107023904 magId "3107023904" @default.
- W3107023904 workType "dissertation" @default.