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- W3107052810 abstract "Introduction: Phosphoinositide 3-kinase (PI3K) inhibitors are a new class of cancer therapy—the first FDA-approved PI3K inhibitor was idelalisib for chronic lymphocytic leukemia in July 2014. They inhibit one or more enzymes in the PI3K/AKT/mTOR pathway that ultimately leads to tumor growth suppression. Cutaneous adverse events (CAEs) appear as frequently as 10%-13% in patient receiving idelalisib with 2% of patients experiencing high grade rashes. Although higher grade CAEs have been described clinically, there is a lack of studies that further characterize CAEs, treatment impact, time to resolution, and response to dermatologic intervention." @default.
- W3107052810 created "2020-12-07" @default.
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- W3107052810 date "2020-12-01" @default.
- W3107052810 modified "2023-10-18" @default.
- W3107052810 title "15192 Retrospective chart review of cutaneous adverse events associated with PI3K inhibitors in 15 patients" @default.
- W3107052810 doi "https://doi.org/10.1016/j.jaad.2020.06.214" @default.
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