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- W3107263792 abstract "Physical exercise induces acute physiological changes leading to enhanced tissue cross-talk and a liberation of extracellular vesicles (EVs) into the circulation. EVs are cell-derived membranous entities which carry bioactive material, such as proteins and RNA species, and are important mediators of cell-cell-communication. Different types of physical exercise interventions trigger the release of diverse EV subpopulations, which are hypothesized to be involved in physiological adaptation processes leading to health benefits and longevity. Large EVs (“microvesicles” and “microparticles”) are studied frequently in the context of physical exercise using straight forward flow cytometry approaches. However, the analysis of small EVs (sEVs) including exosomes is hampered by the complex composition of blood, confounding the methodology of EV isolation and characterization. This mini review presents a concise overview of the current state of research on sEVs released upon physical exercise (ExerVs), highlighting the technical limits of ExerV analysis. The purity of EV preparations is highly influenced by the co-isolation of non-EV structures in the size range or density of EVs, such as lipoproteins and protein aggregates. Technical constraints associated with EV purification challenge the quantification of distinct ExerV populations, the identification of their cargo, and the investigation of their biological functions. Here, we offer recommendations for the isolation and characterization of ExerVs to minimize the effects of these drawbacks. Technological advances in the ExerV research field will improve understanding of the inter-cellular cross-talk induced by physical exercise leading to health benefits." @default.
- W3107263792 created "2020-12-07" @default.
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- W3107263792 date "2020-12-03" @default.
- W3107263792 modified "2023-10-17" @default.
- W3107263792 title "Considerations for the Analysis of Small Extracellular Vesicles in Physical Exercise" @default.
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- W3107263792 cites W1917937260 @default.
- W3107263792 cites W1931006327 @default.
- W3107263792 cites W1965152917 @default.
- W3107263792 cites W1968081342 @default.
- W3107263792 cites W1971853030 @default.
- W3107263792 cites W1992226521 @default.
- W3107263792 cites W2013057431 @default.
- W3107263792 cites W2020863352 @default.
- W3107263792 cites W2032696674 @default.
- W3107263792 cites W2033112925 @default.
- W3107263792 cites W2044638539 @default.
- W3107263792 cites W2085461145 @default.
- W3107263792 cites W2098259366 @default.
- W3107263792 cites W2098847286 @default.
- W3107263792 cites W2134224248 @default.
- W3107263792 cites W2146558097 @default.
- W3107263792 cites W2147356401 @default.
- W3107263792 cites W2164210247 @default.
- W3107263792 cites W2169894204 @default.
- W3107263792 cites W2170194949 @default.
- W3107263792 cites W2170852633 @default.
- W3107263792 cites W219060072 @default.
- W3107263792 cites W2200617834 @default.
- W3107263792 cites W2235604943 @default.
- W3107263792 cites W2259481044 @default.
- W3107263792 cites W2274860869 @default.
- W3107263792 cites W2338060077 @default.
- W3107263792 cites W2343616244 @default.
- W3107263792 cites W2409619909 @default.
- W3107263792 cites W2500122991 @default.
- W3107263792 cites W2519321703 @default.
- W3107263792 cites W2520566087 @default.
- W3107263792 cites W2522821491 @default.
- W3107263792 cites W2528350440 @default.
- W3107263792 cites W2540034041 @default.
- W3107263792 cites W2594599876 @default.
- W3107263792 cites W2613327265 @default.
- W3107263792 cites W2617321540 @default.
- W3107263792 cites W2734579447 @default.
- W3107263792 cites W2747765265 @default.
- W3107263792 cites W2758479260 @default.
- W3107263792 cites W2770429106 @default.
- W3107263792 cites W2781579322 @default.
- W3107263792 cites W2782804476 @default.
- W3107263792 cites W2785371699 @default.
- W3107263792 cites W2786514708 @default.
- W3107263792 cites W2789992655 @default.
- W3107263792 cites W2790701366 @default.
- W3107263792 cites W2799875505 @default.
- W3107263792 cites W2806952534 @default.
- W3107263792 cites W2809226931 @default.
- W3107263792 cites W2809441834 @default.
- W3107263792 cites W2810287644 @default.
- W3107263792 cites W2888605510 @default.
- W3107263792 cites W2888695934 @default.
- W3107263792 cites W2900756811 @default.
- W3107263792 cites W2901852089 @default.
- W3107263792 cites W2922418593 @default.
- W3107263792 cites W2923606319 @default.
- W3107263792 cites W2933304441 @default.
- W3107263792 cites W2938866342 @default.
- W3107263792 cites W2944439533 @default.
- W3107263792 cites W2947396354 @default.
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- W3107263792 cites W2999852770 @default.
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- W3107263792 cites W3014145011 @default.
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- W3107263792 doi "https://doi.org/10.3389/fphys.2020.576150" @default.
- W3107263792 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7744614" @default.
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- W3107263792 hasPublicationYear "2020" @default.
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