Matches in SemOpenAlex for { <https://semopenalex.org/work/W3107450242> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3107450242 abstract "Abstract The prevalence of rheumatoid arthritis (RA) is higher in females than in males. With the development of new treatment options and strategies such as biologics, we found it worthwhile to identify whether males and females warrant different treatment regimens to ensure the best clinical response. Our meta‐analysis included 11 clinical trials of RA patients in support of the Food and Drug Administration's approval of 6 biological products. We evaluated the data of American College of Rheumatology 20 (ACR20) 24 or 26 weeks after treatment. Logistic regression models were applied to compute the odds ratio (OR) of treatment responses between sexes. The ORs of ACR20 response rates in males and females were similar across all studies and not significantly different in overall studies (OR, 1.05; 95% confidence interval, 0.96‐1.16) analyzed with a fixed‐effects model. Further analyses on the 7 ACR20 subcomponents showed high heterogeneity among studies (Q statistic P < .00007, I 2 > 95%), with no observed clinically meaningful sex‐related difference. Thus, our meta‐analysis did not find significant difference in ACR20 response rates between male and female RA patients treated with biologics at approved dosing regimens. This result supports the current clinical practice of not requiring sex‐dependent treatment regimens for RA patients." @default.
- W3107450242 created "2020-12-07" @default.
- W3107450242 creator A5003284474 @default.
- W3107450242 creator A5013453267 @default.
- W3107450242 creator A5020809914 @default.
- W3107450242 creator A5035600823 @default.
- W3107450242 creator A5046914865 @default.
- W3107450242 creator A5056368358 @default.
- W3107450242 creator A5062972256 @default.
- W3107450242 creator A5065821595 @default.
- W3107450242 creator A5082979652 @default.
- W3107450242 creator A5090154416 @default.
- W3107450242 date "2020-12-01" @default.
- W3107450242 modified "2023-09-27" @default.
- W3107450242 title "Impact of Sex on Clinical Response in Rheumatoid Arthritis Patients Treated With Biologics at Approved Dosing Regimens" @default.
- W3107450242 cites W1543098232 @default.
- W3107450242 cites W1966968999 @default.
- W3107450242 cites W1976068756 @default.
- W3107450242 cites W1978768660 @default.
- W3107450242 cites W1982070737 @default.
- W3107450242 cites W1985213109 @default.
- W3107450242 cites W1990509922 @default.
- W3107450242 cites W2007786715 @default.
- W3107450242 cites W2014818337 @default.
- W3107450242 cites W2061116250 @default.
- W3107450242 cites W2091361933 @default.
- W3107450242 cites W2095625290 @default.
- W3107450242 cites W2097019163 @default.
- W3107450242 cites W2099162990 @default.
- W3107450242 cites W2114235410 @default.
- W3107450242 cites W2125435699 @default.
- W3107450242 cites W2130262017 @default.
- W3107450242 cites W2130631271 @default.
- W3107450242 cites W2143480673 @default.
- W3107450242 cites W2159106700 @default.
- W3107450242 cites W2162370292 @default.
- W3107450242 cites W2261212311 @default.
- W3107450242 cites W2808102887 @default.
- W3107450242 cites W4210968471 @default.
- W3107450242 cites W63181469 @default.
- W3107450242 doi "https://doi.org/10.1002/jcph.1776" @default.
- W3107450242 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33274512" @default.
- W3107450242 hasPublicationYear "2020" @default.
- W3107450242 type Work @default.
- W3107450242 sameAs 3107450242 @default.
- W3107450242 citedByCount "5" @default.
- W3107450242 countsByYear W31074502422020 @default.
- W3107450242 countsByYear W31074502422021 @default.
- W3107450242 countsByYear W31074502422022 @default.
- W3107450242 crossrefType "journal-article" @default.
- W3107450242 hasAuthorship W3107450242A5003284474 @default.
- W3107450242 hasAuthorship W3107450242A5013453267 @default.
- W3107450242 hasAuthorship W3107450242A5020809914 @default.
- W3107450242 hasAuthorship W3107450242A5035600823 @default.
- W3107450242 hasAuthorship W3107450242A5046914865 @default.
- W3107450242 hasAuthorship W3107450242A5056368358 @default.
- W3107450242 hasAuthorship W3107450242A5062972256 @default.
- W3107450242 hasAuthorship W3107450242A5065821595 @default.
- W3107450242 hasAuthorship W3107450242A5082979652 @default.
- W3107450242 hasAuthorship W3107450242A5090154416 @default.
- W3107450242 hasBestOaLocation W31074502421 @default.
- W3107450242 hasConcept C126322002 @default.
- W3107450242 hasConcept C151956035 @default.
- W3107450242 hasConcept C156957248 @default.
- W3107450242 hasConcept C198451711 @default.
- W3107450242 hasConcept C2777288759 @default.
- W3107450242 hasConcept C2777575956 @default.
- W3107450242 hasConcept C44249647 @default.
- W3107450242 hasConcept C535046627 @default.
- W3107450242 hasConcept C71924100 @default.
- W3107450242 hasConceptScore W3107450242C126322002 @default.
- W3107450242 hasConceptScore W3107450242C151956035 @default.
- W3107450242 hasConceptScore W3107450242C156957248 @default.
- W3107450242 hasConceptScore W3107450242C198451711 @default.
- W3107450242 hasConceptScore W3107450242C2777288759 @default.
- W3107450242 hasConceptScore W3107450242C2777575956 @default.
- W3107450242 hasConceptScore W3107450242C44249647 @default.
- W3107450242 hasConceptScore W3107450242C535046627 @default.
- W3107450242 hasConceptScore W3107450242C71924100 @default.
- W3107450242 hasIssue "S2" @default.
- W3107450242 hasLocation W31074502421 @default.
- W3107450242 hasOpenAccess W3107450242 @default.
- W3107450242 hasPrimaryLocation W31074502421 @default.
- W3107450242 hasRelatedWork W2037611947 @default.
- W3107450242 hasRelatedWork W2138334887 @default.
- W3107450242 hasRelatedWork W2218945907 @default.
- W3107450242 hasRelatedWork W2335988042 @default.
- W3107450242 hasRelatedWork W2583387738 @default.
- W3107450242 hasRelatedWork W2772777539 @default.
- W3107450242 hasRelatedWork W2971695752 @default.
- W3107450242 hasRelatedWork W3010075638 @default.
- W3107450242 hasRelatedWork W4293569637 @default.
- W3107450242 hasRelatedWork W4322739880 @default.
- W3107450242 hasVolume "60" @default.
- W3107450242 isParatext "false" @default.
- W3107450242 isRetracted "false" @default.
- W3107450242 magId "3107450242" @default.
- W3107450242 workType "article" @default.