Matches in SemOpenAlex for { <https://semopenalex.org/work/W3107497725> ?p ?o ?g. }
- W3107497725 endingPage "127718" @default.
- W3107497725 startingPage "127718" @default.
- W3107497725 abstract "The search for new antimicrobial agents is greater than ever due to the perpetual threat of multidrug resistance in known pathogens and the relentless emergence of new infections. In this manuscript, ten thiazole-based thiazolidinone hybrids bearing a 6-trifluoromethoxy substituent on the benzothiazole core were synthesized and evaluated against a panel of four bacterial strains Salmonella typhimurium, Staphylococcus aureus, Escherichia coli and Listeria monocytogenes and three resistant strains Pseudomonas aeruginosa, E. coli and MRSA. The evaluation of minimum bactericidal and minimum inhibitory concentrations was accomplished by microdilution assay. As reference compounds ampicillin and streptomycin were employed. All compounds displayed antibacterial efficiencies with MBCs/MICs at 0.25–1 mg/mL and 0.12–1 mg/mL respectively while ampicillin displayed MBCs/MICs at 0.15–0.3 mg/mL and at 0.1–0.2 mg/mL respectively. MICs/MBC of streptomycin varied from 0.05 to 0.15 mg/mL and from 0.1 to 0.3 mg/mL respectively. The best overall effect was observed for compound h4, while compound h1 exhibited the highest effective action against E. coli (MIC/MBC 0.12/0.25 mg/ml) among all tested compounds." @default.
- W3107497725 created "2020-12-07" @default.
- W3107497725 creator A5024596501 @default.
- W3107497725 creator A5033981454 @default.
- W3107497725 creator A5041216662 @default.
- W3107497725 creator A5061770993 @default.
- W3107497725 creator A5085906663 @default.
- W3107497725 creator A5086912125 @default.
- W3107497725 creator A5088211625 @default.
- W3107497725 date "2021-01-01" @default.
- W3107497725 modified "2023-10-14" @default.
- W3107497725 title "2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies" @default.
- W3107497725 cites W2050440037 @default.
- W3107497725 cites W2098627421 @default.
- W3107497725 cites W2104595489 @default.
- W3107497725 cites W2134055666 @default.
- W3107497725 cites W2147499591 @default.
- W3107497725 cites W2283808938 @default.
- W3107497725 cites W2344385151 @default.
- W3107497725 cites W2411850008 @default.
- W3107497725 cites W2467187261 @default.
- W3107497725 cites W2553842927 @default.
- W3107497725 cites W2560851361 @default.
- W3107497725 cites W2600790907 @default.
- W3107497725 cites W2771530406 @default.
- W3107497725 cites W2789495552 @default.
- W3107497725 cites W2793653487 @default.
- W3107497725 cites W2804164318 @default.
- W3107497725 cites W2887011246 @default.
- W3107497725 cites W2890377571 @default.
- W3107497725 cites W2891799195 @default.
- W3107497725 cites W2893737843 @default.
- W3107497725 cites W2897931679 @default.
- W3107497725 cites W2898618338 @default.
- W3107497725 cites W2904265364 @default.
- W3107497725 cites W2905794687 @default.
- W3107497725 cites W2911789490 @default.
- W3107497725 cites W2911835481 @default.
- W3107497725 cites W2919433108 @default.
- W3107497725 cites W2992038112 @default.
- W3107497725 cites W2997925093 @default.
- W3107497725 cites W2999916778 @default.
- W3107497725 cites W3003802416 @default.
- W3107497725 cites W3005406265 @default.
- W3107497725 cites W3013073252 @default.
- W3107497725 cites W3013811742 @default.
- W3107497725 cites W3021313895 @default.
- W3107497725 cites W3023571643 @default.
- W3107497725 cites W3029316877 @default.
- W3107497725 cites W3033371523 @default.
- W3107497725 cites W3038478623 @default.
- W3107497725 cites W3044542086 @default.
- W3107497725 cites W3047379798 @default.
- W3107497725 cites W3047526954 @default.
- W3107497725 cites W4236502014 @default.
- W3107497725 doi "https://doi.org/10.1016/j.bmcl.2020.127718" @default.
- W3107497725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33253880" @default.
- W3107497725 hasPublicationYear "2021" @default.
- W3107497725 type Work @default.
- W3107497725 sameAs 3107497725 @default.
- W3107497725 citedByCount "15" @default.
- W3107497725 countsByYear W31074977252021 @default.
- W3107497725 countsByYear W31074977252022 @default.
- W3107497725 countsByYear W31074977252023 @default.
- W3107497725 crossrefType "journal-article" @default.
- W3107497725 hasAuthorship W3107497725A5024596501 @default.
- W3107497725 hasAuthorship W3107497725A5033981454 @default.
- W3107497725 hasAuthorship W3107497725A5041216662 @default.
- W3107497725 hasAuthorship W3107497725A5061770993 @default.
- W3107497725 hasAuthorship W3107497725A5085906663 @default.
- W3107497725 hasAuthorship W3107497725A5086912125 @default.
- W3107497725 hasAuthorship W3107497725A5088211625 @default.
- W3107497725 hasConcept C104317684 @default.
- W3107497725 hasConcept C176947019 @default.
- W3107497725 hasConcept C178790620 @default.
- W3107497725 hasConcept C185592680 @default.
- W3107497725 hasConcept C26381139 @default.
- W3107497725 hasConcept C2775843808 @default.
- W3107497725 hasConcept C2777456753 @default.
- W3107497725 hasConcept C2778464347 @default.
- W3107497725 hasConcept C2779489039 @default.
- W3107497725 hasConcept C2780950330 @default.
- W3107497725 hasConcept C2781350384 @default.
- W3107497725 hasConcept C4937899 @default.
- W3107497725 hasConcept C501593827 @default.
- W3107497725 hasConcept C523546767 @default.
- W3107497725 hasConcept C54355233 @default.
- W3107497725 hasConcept C547475151 @default.
- W3107497725 hasConcept C55493867 @default.
- W3107497725 hasConcept C71240020 @default.
- W3107497725 hasConcept C86803240 @default.
- W3107497725 hasConcept C89423630 @default.
- W3107497725 hasConceptScore W3107497725C104317684 @default.
- W3107497725 hasConceptScore W3107497725C176947019 @default.
- W3107497725 hasConceptScore W3107497725C178790620 @default.
- W3107497725 hasConceptScore W3107497725C185592680 @default.
- W3107497725 hasConceptScore W3107497725C26381139 @default.
- W3107497725 hasConceptScore W3107497725C2775843808 @default.