Matches in SemOpenAlex for { <https://semopenalex.org/work/W3107603614> ?p ?o ?g. }
- W3107603614 endingPage "273" @default.
- W3107603614 startingPage "264" @default.
- W3107603614 abstract "Anthelmintic resistance is a significant threat to livestock production systems worldwide and is emerging as an important issue in companion animal parasite management. It is also an emerging concern for the control of human soil-transmitted helminths and filaria. An important aspect of managing anthelmintic resistance is the ability to utilise diagnostic tests to detect its emergence at an early stage. In host-parasite systems where resistance is already widespread, diagnostics have a potentially important role in determining those drugs that remain the most effective. The development of molecular diagnostics for anthelmintic resistance is one focus of the Consortium for Anthelmintic Resistance and Susceptibility (CARS) group. The present paper reflects discussions of this issue that occurred at the most recent meeting of the group in Wisconsin, USA, in July 2019. We compare molecular resistance diagnostics with in vivo and in vitro phenotypic methods, and highlight the advantages and disadvantages of each. We assess whether our knowledge on the identity of molecular markers for resistance towards the different drug classes is sufficient to provide some expectation that molecular tests for field use may be available in the short-to-medium term. We describe some practical aspects of such tests and how our current capabilities compare to the requirements of an 'ideal' test. Finally, we describe examples of drug class/parasite species interactions that provide the best opportunity for commercial use of molecular tests in the near future. We argue that while such prototype tests may not satisfy the requirements of an 'ideal' test, their potential to provide significant advances over currently-used phenotypic methods warrants their development as field diagnostics." @default.
- W3107603614 created "2020-12-07" @default.
- W3107603614 creator A5011023136 @default.
- W3107603614 creator A5021518732 @default.
- W3107603614 creator A5058811797 @default.
- W3107603614 creator A5073368410 @default.
- W3107603614 date "2020-12-01" @default.
- W3107603614 modified "2023-10-17" @default.
- W3107603614 title "Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance" @default.
- W3107603614 cites W1662661308 @default.
- W3107603614 cites W1757271791 @default.
- W3107603614 cites W1954391111 @default.
- W3107603614 cites W1964598386 @default.
- W3107603614 cites W1967133850 @default.
- W3107603614 cites W1976628678 @default.
- W3107603614 cites W1978825531 @default.
- W3107603614 cites W1985020242 @default.
- W3107603614 cites W1989706787 @default.
- W3107603614 cites W1993617925 @default.
- W3107603614 cites W1998203682 @default.
- W3107603614 cites W2000960824 @default.
- W3107603614 cites W2002861734 @default.
- W3107603614 cites W2003446114 @default.
- W3107603614 cites W2006693262 @default.
- W3107603614 cites W2010124676 @default.
- W3107603614 cites W2010230299 @default.
- W3107603614 cites W2010938961 @default.
- W3107603614 cites W2012727279 @default.
- W3107603614 cites W2016276858 @default.
- W3107603614 cites W2018753422 @default.
- W3107603614 cites W2018998736 @default.
- W3107603614 cites W2019454741 @default.
- W3107603614 cites W2020300669 @default.
- W3107603614 cites W2022683792 @default.
- W3107603614 cites W2025538412 @default.
- W3107603614 cites W2033474948 @default.
- W3107603614 cites W2037645437 @default.
- W3107603614 cites W2040889380 @default.
- W3107603614 cites W2041327979 @default.
- W3107603614 cites W2041418728 @default.
- W3107603614 cites W2043375010 @default.
- W3107603614 cites W2044047854 @default.
- W3107603614 cites W2051036114 @default.
- W3107603614 cites W2058983590 @default.
- W3107603614 cites W2059037153 @default.
- W3107603614 cites W2067372648 @default.
- W3107603614 cites W2070516735 @default.
- W3107603614 cites W2070706872 @default.
- W3107603614 cites W2077740759 @default.
- W3107603614 cites W2090690189 @default.
- W3107603614 cites W2092306308 @default.
- W3107603614 cites W2095282287 @default.
- W3107603614 cites W2095303104 @default.
- W3107603614 cites W2102117113 @default.
- W3107603614 cites W2111191097 @default.
- W3107603614 cites W2115594545 @default.
- W3107603614 cites W2129083618 @default.
- W3107603614 cites W2137876113 @default.
- W3107603614 cites W2143052395 @default.
- W3107603614 cites W2161747928 @default.
- W3107603614 cites W2170050310 @default.
- W3107603614 cites W2188533297 @default.
- W3107603614 cites W2253114563 @default.
- W3107603614 cites W2347783381 @default.
- W3107603614 cites W2393966434 @default.
- W3107603614 cites W2400294151 @default.
- W3107603614 cites W2497850966 @default.
- W3107603614 cites W2535049120 @default.
- W3107603614 cites W2558205417 @default.
- W3107603614 cites W2559577985 @default.
- W3107603614 cites W2560755574 @default.
- W3107603614 cites W2579171437 @default.
- W3107603614 cites W2611505266 @default.
- W3107603614 cites W2613390002 @default.
- W3107603614 cites W2671985949 @default.
- W3107603614 cites W2684799697 @default.
- W3107603614 cites W2742621197 @default.
- W3107603614 cites W2750626707 @default.
- W3107603614 cites W2759758131 @default.
- W3107603614 cites W2765901796 @default.
- W3107603614 cites W2767403507 @default.
- W3107603614 cites W2767545190 @default.
- W3107603614 cites W2767971152 @default.
- W3107603614 cites W2780728213 @default.
- W3107603614 cites W2781385164 @default.
- W3107603614 cites W2794032135 @default.
- W3107603614 cites W2801276908 @default.
- W3107603614 cites W2804942785 @default.
- W3107603614 cites W2807859748 @default.
- W3107603614 cites W2884048087 @default.
- W3107603614 cites W2886948027 @default.
- W3107603614 cites W2891721431 @default.
- W3107603614 cites W2900719667 @default.
- W3107603614 cites W2911339480 @default.
- W3107603614 cites W2911807104 @default.
- W3107603614 cites W2922010013 @default.
- W3107603614 cites W2951131794 @default.
- W3107603614 cites W2964653278 @default.