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- W3107723330 abstract "Noninvasive brain stimulation is a novel treatment avenue for attention-deficit/hyperactivity disorder (ADHD). The advantages over pharmacological treatment are relatively minimal and transient side-effects, which make it a treatment preferred by patients and parents. Neurostimulation can furthermore target key neurobiological abnormalities established over decades of neuroimaging research. Trigeminal nerve stimulation (TNS) is the only neuromodulation and device-based nonpharmacological treatment recently licensed for children with ADHD by the US Food and Drug Administration. This was based on a double-blind sham-controlled proof-of-concept trial of 4 weeks of TNS in 62 children, who showed a reduction of ADHD symptoms with an effect size of 0.5, similar to the results with second-line nonstimulant pharmacological treatment.1 Precision medicine approaches, such as establishing predictors of treatment response using relatively cost-effective cognitive and electrophysiological measures would be clinically very useful to screen children with ADHD for whom TNS is likely to be effective." @default.
- W3107723330 created "2020-12-07" @default.
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- W3107723330 date "2021-07-01" @default.
- W3107723330 modified "2023-09-24" @default.
- W3107723330 title "Editorial: Precision Medicine in Neurotherapeutics for Attention-Deficit/Hyperactivity Disorder" @default.
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- W3107723330 doi "https://doi.org/10.1016/j.jaac.2020.11.013" @default.
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