FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3107773344> ?p ?o ?g. }

• W3107773344 abstract "Abstract Background Long-term basic pharmacotherapy may have a major impact upon clinical course and survival in patients with stable coronary artery diseases (CAD) after isolated coronary artery bypass grafting (CABG). Purpose To determine the role of compliance with guideline-directed basic pharmacotherapy in the prevention of late major adverse clinical events (MAEs) in patients with stable CAD after isolated CABG at 3-year follow-up. Methods A single-centre study included 576 patients with stable CAD, consecutively enrolled for isolated CABG during the period 2011–2017. Follow-up median was 34 months (interquartile range 13–60 months). Two (0.3%) patients died early after CABG, thus 574 (99.7%) patients were followed post-discharge. At 3-year follow-up, data on MAEs were available in 251 patients, mean age (61±9) years, 218 (86.9%) males. Among them, MAEs occurred in 55 (21.9%) cases. Results Basic CAD pharmacotherapy after CABG was comparable in MAEs vs. no-MAEs groups, with the vast majority of patients receiving guideline-recommended therapy at discharge, namely angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin-II receptors blockers (ARBs) (79.6% vs. 88.8%, respectively; p=0.109), statins (98.1% vs. 99.0%, respectively; p=0.619) and antiplatelet drugs (98.1% vs. 99.5%, respectively; p=0.327). At 3-year follow-up, MAEs group, as opposed to no-MAEs group, was characterized by the lower usage of ACEI/ARBs (68.5% vs. 87.2%, respectively; p=0.001) and statins (59.3% vs. 86.7%, respectively; p&lt;0.001), as well as triple basic CAD therapy (ACEI or ARBs/statins/antiplatelet drugs: 35.2% vs. 70.4%, respectively; p&lt;0.001). Conclusion At 3-year follow-up, MAEs in patients with stable CAD after isolated CABG were associated with more frequent discontinuation of previously prescribed guideline-directed basic pharmacotherapy, namely ACEI/ARBs and statins, as well as triple basic CAD therapy. Funding Acknowledgement Type of funding source: None" @default.
• W3107773344 created "2020-12-07" @default.
• W3107773344 creator A5003591278 @default.
• W3107773344 creator A5036639338 @default.
• W3107773344 creator A5060284667 @default.
• W3107773344 creator A5072891840 @default.
• W3107773344 creator A5083435676 @default.
• W3107773344 date "2020-11-01" @default.
• W3107773344 modified "2023-09-23" @default.
• W3107773344 title "Compliance with guideline-directed basic pharmacotherapy and late adverse events in patients with stable coronary artery disease after isolated surgical revascularization" @default.
• W3107773344 doi "https://doi.org/10.1093/ehjci/ehaa946.1459" @default.
• W3107773344 hasPublicationYear "2020" @default.
• W3107773344 type Work @default.
• W3107773344 sameAs 3107773344 @default.
• W3107773344 citedByCount "0" @default.
• W3107773344 crossrefType "journal-article" @default.
• W3107773344 hasAuthorship W3107773344A5003591278 @default.
• W3107773344 hasAuthorship W3107773344A5036639338 @default.
• W3107773344 hasAuthorship W3107773344A5060284667 @default.
• W3107773344 hasAuthorship W3107773344A5072891840 @default.
• W3107773344 hasAuthorship W3107773344A5083435676 @default.
• W3107773344 hasConcept C119060515 @default.
• W3107773344 hasConcept C126322002 @default.
• W3107773344 hasConcept C141071460 @default.
• W3107773344 hasConcept C142724271 @default.
• W3107773344 hasConcept C164705383 @default.
• W3107773344 hasConcept C197934379 @default.
• W3107773344 hasConcept C2778213512 @default.
• W3107773344 hasConcept C2779464278 @default.
• W3107773344 hasConcept C2780182762 @default.
• W3107773344 hasConcept C500440147 @default.
• W3107773344 hasConcept C500558357 @default.
• W3107773344 hasConcept C71924100 @default.
• W3107773344 hasConceptScore W3107773344C119060515 @default.
• W3107773344 hasConceptScore W3107773344C126322002 @default.
• W3107773344 hasConceptScore W3107773344C141071460 @default.
• W3107773344 hasConceptScore W3107773344C142724271 @default.
• W3107773344 hasConceptScore W3107773344C164705383 @default.
• W3107773344 hasConceptScore W3107773344C197934379 @default.
• W3107773344 hasConceptScore W3107773344C2778213512 @default.
• W3107773344 hasConceptScore W3107773344C2779464278 @default.
• W3107773344 hasConceptScore W3107773344C2780182762 @default.
• W3107773344 hasConceptScore W3107773344C500440147 @default.
• W3107773344 hasConceptScore W3107773344C500558357 @default.
• W3107773344 hasConceptScore W3107773344C71924100 @default.
• W3107773344 hasLocation W31077733441 @default.
• W3107773344 hasOpenAccess W3107773344 @default.
• W3107773344 hasPrimaryLocation W31077733441 @default.
• W3107773344 hasRelatedWork W1028115 @default.
• W3107773344 hasRelatedWork W10719345 @default.
• W3107773344 hasRelatedWork W11090947 @default.
• W3107773344 hasRelatedWork W13223429 @default.
• W3107773344 hasRelatedWork W1494155 @default.
• W3107773344 hasRelatedWork W3058041 @default.
• W3107773344 hasRelatedWork W3242620 @default.
• W3107773344 hasRelatedWork W4989377 @default.
• W3107773344 hasRelatedWork W7071295 @default.
• W3107773344 hasRelatedWork W9192601 @default.
• W3107773344 isParatext "false" @default.
• W3107773344 isRetracted "false" @default.
• W3107773344 magId "3107773344" @default.
• W3107773344 workType "article" @default.