FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3107887848> ?p ?o ?g. }

• W3107887848 endingPage "252" @default.
• W3107887848 startingPage "252" @default.
• W3107887848 abstract "In the precision medicine era, molecular testing in advanced cancer is foundational to patient management. Molecular tumor boards (MTBs) can be effective in processing comprehensive genomic profiling (CGP) results and providing expert recommendations. We assessed an MTB and its role in a community setting. This retrospective analysis included patients with MTB recommendations at a community-based oncology practice January 2015 to December 2018; exclusions were death within 60 days of the MTB and/or no metastatic disease. Potentially actionable genomic alterations from CGP (immunohistochemistry, in-situ hybridization, next-generation sequencing) were reviewed bi-weekly by MTB practice experts, pathologists, genetic counselors, and other support staff, and clinical care recommendations were provided. Subsequent chart reviews determined implementation rates of recommendations. In 613 patients, the most common cancers were lung (23%), breast (19%), and colorectal (17%); others included ovarian, endometrial, bladder, and melanoma. Patients received 837 actionable recommendations: standard therapy (37%), clinical trial (31%), germline testing and genetic counseling (17%), off-label therapy (10%), subspecialty multidisciplinary tumor board review (2%), and advice for classifying tumor of unknown origin (2%). Of these recommendations, 36% to 78% were followed by the treating physician. For clinical trial recommendations (n = 262), 13% of patients enrolled in a clinical trial. The median time between CPG result availability and MTB presentation was 12 days. A community oncology-based comprehensive and high-throughput MTB provided useful clinical guidance in various treatment domains within an acceptable timeframe for patients with cancer in a large community setting." @default.
• W3107887848 created "2020-12-07" @default.
• W3107887848 creator A5020694447 @default.
• W3107887848 creator A5038120683 @default.
• W3107887848 creator A5043065014 @default.
• W3107887848 creator A5045207535 @default.
• W3107887848 creator A5057458005 @default.
• W3107887848 creator A5072563567 @default.
• W3107887848 creator A5073189857 @default.
• W3107887848 date "2020-11-27" @default.
• W3107887848 modified "2023-10-03" @default.
• W3107887848 title "Establishment of a Molecular Tumor Board (MTB) and Uptake of Recommendations in a Community Setting" @default.
• W3107887848 cites W1980852206 @default.
• W3107887848 cites W2119133440 @default.
• W3107887848 cites W2127250774 @default.
• W3107887848 cites W2148565184 @default.
• W3107887848 cites W2345898309 @default.
• W3107887848 cites W2551013093 @default.
• W3107887848 cites W2586443587 @default.
• W3107887848 cites W2591662301 @default.
• W3107887848 cites W2681535791 @default.
• W3107887848 cites W2757648331 @default.
• W3107887848 cites W2763131893 @default.
• W3107887848 cites W2778160167 @default.
• W3107887848 cites W2784538417 @default.
• W3107887848 cites W2795373371 @default.
• W3107887848 cites W2892314803 @default.
• W3107887848 cites W2908847865 @default.
• W3107887848 cites W2935541805 @default.
• W3107887848 cites W2963845618 @default.
• W3107887848 cites W2969414767 @default.
• W3107887848 cites W2988002600 @default.
• W3107887848 doi "https://doi.org/10.3390/jpm10040252" @default.
• W3107887848 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7711773" @default.
• W3107887848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33260805" @default.
• W3107887848 hasPublicationYear "2020" @default.
• W3107887848 type Work @default.
• W3107887848 sameAs 3107887848 @default.
• W3107887848 citedByCount "17" @default.
• W3107887848 countsByYear W31078878482021 @default.
• W3107887848 countsByYear W31078878482022 @default.
• W3107887848 countsByYear W31078878482023 @default.
• W3107887848 crossrefType "journal-article" @default.
• W3107887848 hasAuthorship W3107887848A5020694447 @default.
• W3107887848 hasAuthorship W3107887848A5038120683 @default.
• W3107887848 hasAuthorship W3107887848A5043065014 @default.
• W3107887848 hasAuthorship W3107887848A5045207535 @default.
• W3107887848 hasAuthorship W3107887848A5057458005 @default.
• W3107887848 hasAuthorship W3107887848A5072563567 @default.
• W3107887848 hasAuthorship W3107887848A5073189857 @default.
• W3107887848 hasBestOaLocation W31078878481 @default.
• W3107887848 hasConcept C121608353 @default.
• W3107887848 hasConcept C126322002 @default.
• W3107887848 hasConcept C141071460 @default.
• W3107887848 hasConcept C142724271 @default.
• W3107887848 hasConcept C143998085 @default.
• W3107887848 hasConcept C163763905 @default.
• W3107887848 hasConcept C2776232967 @default.
• W3107887848 hasConcept C2776256026 @default.
• W3107887848 hasConcept C2777106319 @default.
• W3107887848 hasConcept C2779422266 @default.
• W3107887848 hasConcept C2780642338 @default.
• W3107887848 hasConcept C512399662 @default.
• W3107887848 hasConcept C526805850 @default.
• W3107887848 hasConcept C530470458 @default.
• W3107887848 hasConcept C535046627 @default.
• W3107887848 hasConcept C54355233 @default.
• W3107887848 hasConcept C71924100 @default.
• W3107887848 hasConcept C80227256 @default.
• W3107887848 hasConcept C86803240 @default.
• W3107887848 hasConceptScore W3107887848C121608353 @default.
• W3107887848 hasConceptScore W3107887848C126322002 @default.
• W3107887848 hasConceptScore W3107887848C141071460 @default.
• W3107887848 hasConceptScore W3107887848C142724271 @default.
• W3107887848 hasConceptScore W3107887848C143998085 @default.
• W3107887848 hasConceptScore W3107887848C163763905 @default.
• W3107887848 hasConceptScore W3107887848C2776232967 @default.
• W3107887848 hasConceptScore W3107887848C2776256026 @default.
• W3107887848 hasConceptScore W3107887848C2777106319 @default.
• W3107887848 hasConceptScore W3107887848C2779422266 @default.
• W3107887848 hasConceptScore W3107887848C2780642338 @default.
• W3107887848 hasConceptScore W3107887848C512399662 @default.
• W3107887848 hasConceptScore W3107887848C526805850 @default.
• W3107887848 hasConceptScore W3107887848C530470458 @default.
• W3107887848 hasConceptScore W3107887848C535046627 @default.
• W3107887848 hasConceptScore W3107887848C54355233 @default.
• W3107887848 hasConceptScore W3107887848C71924100 @default.
• W3107887848 hasConceptScore W3107887848C80227256 @default.
• W3107887848 hasConceptScore W3107887848C86803240 @default.
• W3107887848 hasIssue "4" @default.
• W3107887848 hasLocation W31078878481 @default.
• W3107887848 hasLocation W31078878482 @default.
• W3107887848 hasLocation W31078878483 @default.
• W3107887848 hasLocation W31078878484 @default.
• W3107887848 hasOpenAccess W3107887848 @default.
• W3107887848 hasPrimaryLocation W31078878481 @default.
• W3107887848 hasRelatedWork W2224319365 @default.
• W3107887848 hasRelatedWork W2372809030 @default.

• next