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- W3107953644 abstract "Abstract Polysaccharide nanoparticles are promising materials in the wide range of disciplines such as medicine, nutrition, food production, agriculture, material science and others. They excel not only in their non‐toxicity and biodegradability but also in their easy preparation. As well as inorganic particles, a protein corona (PC) around polysaccharide nanoparticles is formed in biofluids. Moreover, it has been considered that the overall response of the organism to nanoparticles presence depends on the PC. This review summarises scientific publications about the structural chemistry of polysaccharide nanoparticles and their impact on theranostic applications. Three strategies of implementation of the PC in theranostics have been discussed: I) Utilisation of the PC in therapy; II) How the composition of the PC is analysed for specific disease markers; III) How the formed PC can interact with the immune system and enhances the immunomodulation or immunoelimination. Thus, the findings from this review can contribute to improve the design of drug delivery systems. However, it is still necessary to elucidate the mechanisms of nano‐bio interactions and discover new connections in nanoscale research." @default.
- W3107953644 created "2020-12-07" @default.
- W3107953644 creator A5000022787 @default.
- W3107953644 creator A5009700689 @default.
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- W3107953644 creator A5020343284 @default.
- W3107953644 creator A5026615246 @default.
- W3107953644 creator A5030308349 @default.
- W3107953644 creator A5039907666 @default.
- W3107953644 creator A5047376562 @default.
- W3107953644 date "2020-12-04" @default.
- W3107953644 modified "2023-10-15" @default.
- W3107953644 title "Theranostic Approach for the Protein Corona of Polysaccharide Nanoparticles" @default.
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