Matches in SemOpenAlex for { <https://semopenalex.org/work/W3107996938> ?p ?o ?g. }
- W3107996938 abstract "Abstract Thermoregulation plays a vital role in homeostasis. Many species of animals as well as humans have evolved various physiological mechanisms for body temperature control, which are characteristically flexible and enable a fine‐tuned spatial and temporal regulation of body temperature in different environmental conditions and circumstances. Human beings normally maintain a core body temperature at around 37°C, and maintenance of this relatively high temperature is critical for survival. Therefore, principles of thermoregulatory control have also important clinical implications. Infections can cause the body temperature to rise internally and several diseases can cause a dysfunction of thermoregulatory mechanisms. Moreover, the utilization of thermotherapies in treating various diseases has been known for thousands of years with a recent resurgence of interest. An increasing amount of research suggests that targeted temperature management is of paramount importance to patient outcomes in certain clinical scenarios. We provide a concise summary of the basic concepts of thermoregulation. Emphasis is given to the principles of thermoregulation in humans in basic pathological states and to targeted temperature management strategies in the clinical environment, with special attention on therapeutic hypothermia in postcardiac arrest patients. Finally, the discussion is focused on the potential offered by computational thermophysiological models for predicting thermal responses of patients in various clinical circumstances, for proposing new perspectives in the design of novel thermal therapies, and to optimize targeted temperature management strategies. This article is categorized under: Cardiovascular Diseases > Computational Models Cardiovascular Diseases > Environmental Factors Cardiovascular Diseases > Biomedical Engineering" @default.
- W3107996938 created "2020-12-07" @default.
- W3107996938 creator A5003141020 @default.
- W3107996938 creator A5006588202 @default.
- W3107996938 creator A5008119913 @default.
- W3107996938 creator A5071867549 @default.
- W3107996938 creator A5073579013 @default.
- W3107996938 date "2020-11-29" @default.
- W3107996938 modified "2023-10-17" @default.
- W3107996938 title "Thermoregulation: A journey from physiology to computational models and the intensive care unit" @default.
- W3107996938 cites W1257239120 @default.
- W3107996938 cites W1572554526 @default.
- W3107996938 cites W1573141201 @default.
- W3107996938 cites W1827859968 @default.
- W3107996938 cites W1890090833 @default.
- W3107996938 cites W1916035025 @default.
- W3107996938 cites W1964780834 @default.
- W3107996938 cites W1965748510 @default.
- W3107996938 cites W1970863819 @default.
- W3107996938 cites W1972101599 @default.
- W3107996938 cites W1973514942 @default.
- W3107996938 cites W1977651828 @default.
- W3107996938 cites W1981568716 @default.
- W3107996938 cites W1982794774 @default.
- W3107996938 cites W1989967936 @default.
- W3107996938 cites W1990316584 @default.
- W3107996938 cites W1994367077 @default.
- W3107996938 cites W1999729884 @default.
- W3107996938 cites W2002843252 @default.
- W3107996938 cites W2012494424 @default.
- W3107996938 cites W2012679426 @default.
- W3107996938 cites W2014213308 @default.
- W3107996938 cites W2023966426 @default.
- W3107996938 cites W2027724797 @default.
- W3107996938 cites W2028437902 @default.
- W3107996938 cites W2028726555 @default.
- W3107996938 cites W2029988160 @default.
- W3107996938 cites W2031918231 @default.
- W3107996938 cites W2037036023 @default.
- W3107996938 cites W2039393505 @default.
- W3107996938 cites W2040811723 @default.
- W3107996938 cites W2041722808 @default.
- W3107996938 cites W2042812131 @default.
- W3107996938 cites W2043529554 @default.
- W3107996938 cites W2045965132 @default.
- W3107996938 cites W2048302254 @default.
- W3107996938 cites W2053189845 @default.
- W3107996938 cites W2055554945 @default.
- W3107996938 cites W2062642814 @default.
- W3107996938 cites W2063826711 @default.
- W3107996938 cites W2064358057 @default.
- W3107996938 cites W2069668391 @default.
- W3107996938 cites W2073559633 @default.
- W3107996938 cites W2074145884 @default.
- W3107996938 cites W2076769048 @default.
- W3107996938 cites W2076856953 @default.
- W3107996938 cites W2084445626 @default.
- W3107996938 cites W2085169843 @default.
- W3107996938 cites W2088336119 @default.
- W3107996938 cites W2089990379 @default.
- W3107996938 cites W2093563778 @default.
- W3107996938 cites W2093816361 @default.
- W3107996938 cites W2096117135 @default.
- W3107996938 cites W2097019501 @default.
- W3107996938 cites W2098101838 @default.
- W3107996938 cites W2098974276 @default.
- W3107996938 cites W2100033072 @default.
- W3107996938 cites W2102443765 @default.
- W3107996938 cites W2104869294 @default.
- W3107996938 cites W2106324948 @default.
- W3107996938 cites W2113197207 @default.
- W3107996938 cites W2113283874 @default.
- W3107996938 cites W2113691221 @default.
- W3107996938 cites W2115044649 @default.
- W3107996938 cites W2116707992 @default.
- W3107996938 cites W2120590735 @default.
- W3107996938 cites W2121054503 @default.
- W3107996938 cites W2121957794 @default.
- W3107996938 cites W2126930161 @default.
- W3107996938 cites W2128106614 @default.
- W3107996938 cites W2128427328 @default.
- W3107996938 cites W2132358997 @default.
- W3107996938 cites W2133285837 @default.
- W3107996938 cites W2135802236 @default.
- W3107996938 cites W2136195590 @default.
- W3107996938 cites W2137234744 @default.
- W3107996938 cites W2145427448 @default.
- W3107996938 cites W2145481802 @default.
- W3107996938 cites W2146587884 @default.
- W3107996938 cites W2148365421 @default.
- W3107996938 cites W2150930940 @default.
- W3107996938 cites W2159711712 @default.
- W3107996938 cites W2164446273 @default.
- W3107996938 cites W2164811721 @default.
- W3107996938 cites W2165958384 @default.
- W3107996938 cites W2170235320 @default.
- W3107996938 cites W2171174186 @default.
- W3107996938 cites W2172418087 @default.
- W3107996938 cites W2180469576 @default.
- W3107996938 cites W2212530770 @default.