FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3108057798> ?p ?o ?g. }

• W3108057798 abstract "Background: Sepsis is a major cause of mortality and morbidity and early diagnosis and timely use of antibiotic therapy is essential for life-threatening condition, at the newborns in PICU.Objective: The aim of this study is to determinate the values of procalcitonin (PCT) on the outcome of patients in pediatric intensive care units (PICUs) and find out if these biomarker can be used to predict sepsis.Methods: The study was designed as a retrospective and prospective, clinical, epidemiological investigation conducted in the period sixth months, which included 45 (M:F=25:20) newborns with two or three clinical signs of sepsis hospitalized in the Intensive Care Unit at the PHI University Clinic for Children Diseases-Skopje. The patient have been divided into two groups: I group included 31 septic newborns with negative blood culture and II group-14 septic newborns with positive blood cultures. Results of blood count (WBC), CRP and PCT, were recorded. Procalcitonin levels were measured by using a immunoassay system Vidas based on the Enzyme Linked Fluorescent Assay (ELFA) principles,at admission and 3-5 days after admission.The third measurement after 6-14 days.The new multiplex polymerase chain reaction–based rapid diagnostic test (BioFire FilmAray Blood Culture Identification (BCID) was used for determinate blood culture.Results: Procalcitonin PCT levels at first 24 hours of the admission were increased in all 45 newborns (≥ 2 ng/mL). The values of C-reactive protein gradually increase after 12-36 hours at admission. The values of WBC increased at 31 newborns, except in 14 pediatric patients with severe sepsis the WBC were decreased (WBC counts <4000). The second measurement, after 3 days usage of an adequate antibiotic treatment, the levels of PCT is decreased, regardless of whether blood culture is positive or negative, except 5 patients develop severe sepsis, and three patients develop septic shock. After the third measurement (6-14 days) the levels of PCT and CRP is decreased. NIV was used in 39.8% patients and Invasive MV was used in 29.8% patients.Sensitivity of procalcitonin 83.5%, Specificity of procalcitonin 81.3%.Conslusion: Procalcitonin (PCT)value is a early prognostic factor for sepsis. The PCT measurement may provide a more rapid means of ruling in or out sepsis provided before availability of blood culture results.The value of PCT of 2 ng/ml is a reliable parameter whether an appropriate antibiotic for the treatment is used,thus increasing newborns safety, reducing costs and reducing the development of antibiotic resistance." @default.
• W3108057798 created "2020-12-07" @default.
• W3108057798 creator A5011396959 @default.
• W3108057798 creator A5014297562 @default.
• W3108057798 creator A5017513218 @default.
• W3108057798 creator A5020057158 @default.
• W3108057798 creator A5039446411 @default.
• W3108057798 creator A5042888211 @default.
• W3108057798 creator A5089557522 @default.
• W3108057798 date "2020-01-01" @default.
• W3108057798 modified "2023-09-27" @default.
• W3108057798 title "Diagnostic Values of InflammatoryMarkers at PICU" @default.
• W3108057798 hasPublicationYear "2020" @default.
• W3108057798 type Work @default.
• W3108057798 sameAs 3108057798 @default.
• W3108057798 citedByCount "0" @default.
• W3108057798 crossrefType "journal-article" @default.
• W3108057798 hasAuthorship W3108057798A5011396959 @default.
• W3108057798 hasAuthorship W3108057798A5014297562 @default.
• W3108057798 hasAuthorship W3108057798A5017513218 @default.
• W3108057798 hasAuthorship W3108057798A5020057158 @default.
• W3108057798 hasAuthorship W3108057798A5039446411 @default.
• W3108057798 hasAuthorship W3108057798A5042888211 @default.
• W3108057798 hasAuthorship W3108057798A5089557522 @default.
• W3108057798 hasConcept C10936531 @default.
• W3108057798 hasConcept C126322002 @default.
• W3108057798 hasConcept C177713679 @default.
• W3108057798 hasConcept C185592680 @default.
• W3108057798 hasConcept C187212893 @default.
• W3108057798 hasConcept C188816634 @default.
• W3108057798 hasConcept C2775953899 @default.
• W3108057798 hasConcept C2776376669 @default.
• W3108057798 hasConcept C2776914184 @default.
• W3108057798 hasConcept C2777091541 @default.
• W3108057798 hasConcept C2778384902 @default.
• W3108057798 hasConcept C2778939556 @default.
• W3108057798 hasConcept C2779473907 @default.
• W3108057798 hasConcept C2781195455 @default.
• W3108057798 hasConcept C2781197716 @default.
• W3108057798 hasConcept C2987404301 @default.
• W3108057798 hasConcept C501593827 @default.
• W3108057798 hasConcept C55493867 @default.
• W3108057798 hasConcept C71924100 @default.
• W3108057798 hasConcept C86803240 @default.
• W3108057798 hasConcept C89423630 @default.
• W3108057798 hasConceptScore W3108057798C10936531 @default.
• W3108057798 hasConceptScore W3108057798C126322002 @default.
• W3108057798 hasConceptScore W3108057798C177713679 @default.
• W3108057798 hasConceptScore W3108057798C185592680 @default.
• W3108057798 hasConceptScore W3108057798C187212893 @default.
• W3108057798 hasConceptScore W3108057798C188816634 @default.
• W3108057798 hasConceptScore W3108057798C2775953899 @default.
• W3108057798 hasConceptScore W3108057798C2776376669 @default.
• W3108057798 hasConceptScore W3108057798C2776914184 @default.
• W3108057798 hasConceptScore W3108057798C2777091541 @default.
• W3108057798 hasConceptScore W3108057798C2778384902 @default.
• W3108057798 hasConceptScore W3108057798C2778939556 @default.
• W3108057798 hasConceptScore W3108057798C2779473907 @default.
• W3108057798 hasConceptScore W3108057798C2781195455 @default.
• W3108057798 hasConceptScore W3108057798C2781197716 @default.
• W3108057798 hasConceptScore W3108057798C2987404301 @default.
• W3108057798 hasConceptScore W3108057798C501593827 @default.
• W3108057798 hasConceptScore W3108057798C55493867 @default.
• W3108057798 hasConceptScore W3108057798C71924100 @default.
• W3108057798 hasConceptScore W3108057798C86803240 @default.
• W3108057798 hasConceptScore W3108057798C89423630 @default.
• W3108057798 hasLocation W31080577981 @default.
• W3108057798 hasOpenAccess W3108057798 @default.
• W3108057798 hasPrimaryLocation W31080577981 @default.
• W3108057798 hasRelatedWork W2092230818 @default.
• W3108057798 hasRelatedWork W2103853352 @default.
• W3108057798 hasRelatedWork W2238090333 @default.
• W3108057798 hasRelatedWork W2284627576 @default.
• W3108057798 hasRelatedWork W2326569310 @default.
• W3108057798 hasRelatedWork W2351402807 @default.
• W3108057798 hasRelatedWork W2352996193 @default.
• W3108057798 hasRelatedWork W2373970525 @default.
• W3108057798 hasRelatedWork W2385102164 @default.
• W3108057798 hasRelatedWork W2386982321 @default.
• W3108057798 hasRelatedWork W2980937628 @default.
• W3108057798 hasRelatedWork W3010973783 @default.
• W3108057798 hasRelatedWork W3018337086 @default.
• W3108057798 hasRelatedWork W3030699669 @default.
• W3108057798 hasRelatedWork W3032703315 @default.
• W3108057798 hasRelatedWork W3083035037 @default.
• W3108057798 hasRelatedWork W3095707035 @default.
• W3108057798 hasRelatedWork W3111206806 @default.
• W3108057798 hasRelatedWork W3130204528 @default.
• W3108057798 hasRelatedWork W87410854 @default.
• W3108057798 isParatext "false" @default.
• W3108057798 isRetracted "false" @default.
• W3108057798 magId "3108057798" @default.
• W3108057798 workType "article" @default.