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• W3108156917 abstract "Background We often meet colonic ulcer when we do colonoscopy for patients. The colonic ulcer is isolate or multiple. We can diagnose some colon ulcer at once. But sometimes we do not recognize what disease of these colon ulcers even if we do a biopsy. So, we tracked some patients with colon ulcer in order to know the etiology of these colon ulcers. Methods A total of 32 cases were enrolled. The mean age was (46.3 ± 14.8) years old (range, 21–70 years). The ratio of male to female was 9:7. The main reasons for patients. Undergoing colonoscopy were abdominal pain, diarrhea, and bloody purulent stool. The symptoms lasted for at least a month or more. The basic information, medical history, clinical manifestations, computed tomography (CT), endoscopy of the patients and pathological examination were analyzed. Results The 32 patients’ colonoscopy showed isolate or multiple colon ulcer. At the same time, we did a biopsy. The histopathology showed mucosal chronic inflammation. Combined with the detailed medical history, lab examination, abdominal CT and colonoscopy, we made the initial diagnosis. 8(25%) were NSAIDs-related colonic ulcer (figure 1). 6(18.8%) were ischemic bowel disease. 3(9.4%) were allergic purpura. 2(6.3%) were Behcet’ disease. 1(3.1%) was Wegener’s granulomatosis (figure 2). There are 12 cases, we did not find a clear etiology of colonic ulcer. We did colonoscopy and multi-slice biopsy for all the patients after 3 months. The 20 patients, who had an initial diagnosis, the colon ulcer changed small even disappear after treatment. The other 12 patients, who had no initial diagnosis without any treatment, 6 of them had no changes in the lesions. The histopathology showed 3 were tuberculosis, 2 developed typical ulcerative colitis, 1 was lymphoma. The ulcerations of the other 3 with no initial diagnosis changed small. But the histopathology showed nonspecific mucosal chronic inflammation. The remaining 3, the lesions had disappeared. The follow-up continues. Conclusions There are various manifestations of colonic ulcer with colonoscopy. A detailed medical history is helpful for our diagnosis. The follow-up is important for no reason colonic ulcer. We should not diagnose and use medicine blindly." @default.
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• W3108156917 date "2020-11-01" @default.
• W3108156917 modified "2023-09-27" @default.
• W3108156917 title "IDDF2020-ABS-0214 The clinical significance of colonic ulcer" @default.
• W3108156917 doi "https://doi.org/10.1136/gutjnl-2020-iddf.125" @default.
• W3108156917 hasPublicationYear "2020" @default.
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