FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3108304890> ?p ?o ?g. }

• W3108304890 endingPage "103" @default.
• W3108304890 startingPage "95" @default.
• W3108304890 abstract "Objectives: Remdesivir has shown promise in the management of patients with COVID-19 although recent studies have shown concerns with its effectiveness in practice. Despite this there is a need to document potential adverse drug events (ADEs) to guide future decisions as limited ADE data available before the COVID-19 pandemic.Methods: Interrogation of WHO VigiBase® from 2015 to 2020 coupled with published studies of ADEs in COVID-19 patients. The main outcome measures are the extent of ADEs broken down by factors including age, seriousness, region and organ.Results: A total 1086 ADEs were reported from the 439 individual case reports up to July 19, 2020, in the VigiBase®, reduced to 1004 once duplicates were excluded. Almost all ADEs concerned COVID-19 patients (92.5%), with an appreciable number from the Americas (67.7%). The majority of ADEs were from males > 45 years and were serious (82.5%). An increase in hepatic enzymes (32.1%), renal injury (14.4%), rise in creatinine levels (11.2%), and respiratory failure (6.4%) were the most frequently reported ADEs.Conclusions: Deterioration of liver and kidney function are frequently observed ADEs with remdesivir; consequently, patients should be monitored for these ADEs. The findings are in line with ADEs included in regulatory authority documents." @default.
• W3108304890 created "2020-12-07" @default.
• W3108304890 creator A5008921780 @default.
• W3108304890 creator A5023949635 @default.
• W3108304890 creator A5028480298 @default.
• W3108304890 creator A5040414451 @default.
• W3108304890 creator A5054621992 @default.
• W3108304890 creator A5070767219 @default.
• W3108304890 creator A5078532240 @default.
• W3108304890 date "2020-12-29" @default.
• W3108304890 modified "2023-10-16" @default.
• W3108304890 title "Rapid review of suspected adverse drug events due to remdesivir in the WHO database; findings and implications" @default.
• W3108304890 cites W1278852767 @default.
• W3108304890 cites W1994532242 @default.
• W3108304890 cites W2004941899 @default.
• W3108304890 cites W2054294193 @default.
• W3108304890 cites W2061880507 @default.
• W3108304890 cites W2085752173 @default.
• W3108304890 cites W2101579911 @default.
• W3108304890 cites W2119649844 @default.
• W3108304890 cites W2145123170 @default.
• W3108304890 cites W2474196877 @default.
• W3108304890 cites W2644404989 @default.
• W3108304890 cites W2756699647 @default.
• W3108304890 cites W2790162016 @default.
• W3108304890 cites W2797268435 @default.
• W3108304890 cites W2803631571 @default.
• W3108304890 cites W2886114583 @default.
• W3108304890 cites W2888809634 @default.
• W3108304890 cites W2894377005 @default.
• W3108304890 cites W2896233929 @default.
• W3108304890 cites W2899762085 @default.
• W3108304890 cites W2911518918 @default.
• W3108304890 cites W2981172364 @default.
• W3108304890 cites W2991491848 @default.
• W3108304890 cites W2994153743 @default.
• W3108304890 cites W2999608673 @default.
• W3108304890 cites W3006676570 @default.
• W3108304890 cites W3009885589 @default.
• W3108304890 cites W3012546754 @default.
• W3108304890 cites W3015490759 @default.
• W3108304890 cites W3015552915 @default.
• W3108304890 cites W3016084006 @default.
• W3108304890 cites W3016806376 @default.
• W3108304890 cites W3018023298 @default.
• W3108304890 cites W3019596330 @default.
• W3108304890 cites W3020095800 @default.
• W3108304890 cites W3022373008 @default.
• W3108304890 cites W3026954076 @default.
• W3108304890 cites W3027630905 @default.
• W3108304890 cites W3032677067 @default.
• W3108304890 cites W3032902719 @default.
• W3108304890 cites W3047148479 @default.
• W3108304890 cites W3080718665 @default.
• W3108304890 cites W3080865813 @default.
• W3108304890 cites W3090929175 @default.
• W3108304890 cites W3092982314 @default.
• W3108304890 cites W3094674956 @default.
• W3108304890 doi "https://doi.org/10.1080/17512433.2021.1856655" @default.
• W3108304890 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7784780" @default.
• W3108304890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33252992" @default.
• W3108304890 hasPublicationYear "2020" @default.
• W3108304890 type Work @default.
• W3108304890 sameAs 3108304890 @default.
• W3108304890 citedByCount "45" @default.
• W3108304890 countsByYear W31083048902020 @default.
• W3108304890 countsByYear W31083048902021 @default.
• W3108304890 countsByYear W31083048902022 @default.
• W3108304890 countsByYear W31083048902023 @default.
• W3108304890 crossrefType "journal-article" @default.
• W3108304890 hasAuthorship W3108304890A5008921780 @default.
• W3108304890 hasAuthorship W3108304890A5023949635 @default.
• W3108304890 hasAuthorship W3108304890A5028480298 @default.
• W3108304890 hasAuthorship W3108304890A5040414451 @default.
• W3108304890 hasAuthorship W3108304890A5054621992 @default.
• W3108304890 hasAuthorship W3108304890A5070767219 @default.
• W3108304890 hasAuthorship W3108304890A5078532240 @default.
• W3108304890 hasBestOaLocation W31083048901 @default.
• W3108304890 hasConcept C126322002 @default.
• W3108304890 hasConcept C159641895 @default.
• W3108304890 hasConcept C17744445 @default.
• W3108304890 hasConcept C177713679 @default.
• W3108304890 hasConcept C194828623 @default.
• W3108304890 hasConcept C197934379 @default.
• W3108304890 hasConcept C199539241 @default.
• W3108304890 hasConcept C2776650110 @default.
• W3108304890 hasConcept C2779134260 @default.
• W3108304890 hasConcept C2780035454 @default.
• W3108304890 hasConcept C3008058167 @default.
• W3108304890 hasConcept C524204448 @default.
• W3108304890 hasConcept C57658597 @default.
• W3108304890 hasConcept C71924100 @default.
• W3108304890 hasConcept C98274493 @default.
• W3108304890 hasConceptScore W3108304890C126322002 @default.
• W3108304890 hasConceptScore W3108304890C159641895 @default.
• W3108304890 hasConceptScore W3108304890C17744445 @default.
• W3108304890 hasConceptScore W3108304890C177713679 @default.
• W3108304890 hasConceptScore W3108304890C194828623 @default.

• next