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- W3108511073 abstract "ABSTRACT Biomolecular condensates, largely by virtue of their material properties, are revolutionizing biology, and yet physical understanding of these properties is lagging. Here I show that the viscoelasticity of condensates can be captured by a simple model, comprising a component where shear relaxation is an exponential function of time and a component that is purely viscous (corresponding to instantaneous shear relaxation). Modulation of intermolecular interactions, e.g., by adding salt, can disparately affect the two components, such that the exponentially-relaxing component may dominate at low salt whereas the purely viscous component may dominate at high salt. Condensates have a tendency to fuse, with the dynamics accelerated by surface tension and impeded by viscosity. For fast-fusion condensates, shear relaxation may become rate-limiting. These insights help narrow the gap in understanding between the biology and physics of biomolecular condensates." @default.
- W3108511073 created "2020-12-07" @default.
- W3108511073 creator A5046197938 @default.
- W3108511073 date "2020-11-27" @default.
- W3108511073 modified "2023-10-18" @default.
- W3108511073 title "Viscoelasticity of biomolecular condensates conforms to the Jeffreys model" @default.
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- W3108511073 doi "https://doi.org/10.1101/2020.11.27.401653" @default.
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