FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3108594910> ?p ?o ?g. }

• W3108594910 endingPage "2754" @default.
• W3108594910 startingPage "2745" @default.
• W3108594910 abstract "Abstract Objective To determine the incidence rate, predictors and outcome of severe infections in a population-based cohort of ANCA-associated vasculitis (AAV). Methods The study included 325 cases of AAV (152 female) diagnosed from 1997 through 2016 from a defined geographic area in Sweden. All severe infection events (requiring hospitalization and treatment with intravenous antimicrobials) were identified. The Birmingham vasculitis activity score (BVAS) was used to evaluate disease activity, and organ damage was assessed using the vasculitis damage index (VDI). Patients were followed from time of AAV diagnosis to death or December 2017. Results A total of 129 (40%) patients suffered at least one severe infection. In 2307 person-years (PY) of follow-up, 210 severe infections were diagnosed. The incidence rate of severe infections was 9.1/100 PY and was highest during the first year following AAV diagnosis at 22.1/100 PY (P &lt; 0.001). Pneumonia, sepsis and urinary tract infection were the most common infections. Opportunistic infections constituted only 6% of all severe infections. In Cox regression analysis age and BVAS at diagnosis were the only factors independently predicting severe infection [hazard ratio: 1.54 (P &lt; 0.001) and 1.27 (P = 0.001), respectively]. Severe infection was associated with poorer prognosis with respect to median VDI score 12 months post-AAV diagnosis, renal survival and mortality. Severe infections were the cause of death in 32 patients (22% of all deaths). Conclusion . Severe infection is a common problem in AAV, with the most important prognostic factors being older age and high disease activity at diagnosis. Severe infections are associated with permanent organ damage and high mortality." @default.
• W3108594910 created "2020-12-07" @default.
• W3108594910 creator A5007888588 @default.
• W3108594910 creator A5028156038 @default.
• W3108594910 creator A5032983734 @default.
• W3108594910 creator A5067715072 @default.
• W3108594910 creator A5070674274 @default.
• W3108594910 date "2020-11-30" @default.
• W3108594910 modified "2023-10-14" @default.
• W3108594910 title "Incidence and predictors of severe infections in ANCA-associated vasculitis: a population-based cohort study" @default.
• W3108594910 cites W1545696043 @default.
• W3108594910 cites W1722255222 @default.
• W3108594910 cites W1925149529 @default.
• W3108594910 cites W1972057477 @default.
• W3108594910 cites W1984702041 @default.
• W3108594910 cites W2008828986 @default.
• W3108594910 cites W2025060860 @default.
• W3108594910 cites W2025393559 @default.
• W3108594910 cites W2042710137 @default.
• W3108594910 cites W2053251763 @default.
• W3108594910 cites W2055864845 @default.
• W3108594910 cites W2063340779 @default.
• W3108594910 cites W2080500076 @default.
• W3108594910 cites W2100809783 @default.
• W3108594910 cites W2101711164 @default.
• W3108594910 cites W2109207289 @default.
• W3108594910 cites W2121602116 @default.
• W3108594910 cites W2129925171 @default.
• W3108594910 cites W2130911389 @default.
• W3108594910 cites W2142419302 @default.
• W3108594910 cites W2147350349 @default.
• W3108594910 cites W2151534030 @default.
• W3108594910 cites W2159417210 @default.
• W3108594910 cites W2160041258 @default.
• W3108594910 cites W2163003110 @default.
• W3108594910 cites W2172114963 @default.
• W3108594910 cites W2312254946 @default.
• W3108594910 cites W2413733416 @default.
• W3108594910 cites W2582318172 @default.
• W3108594910 cites W2590549497 @default.
• W3108594910 cites W2607382700 @default.
• W3108594910 cites W2799829055 @default.
• W3108594910 cites W2808140231 @default.
• W3108594910 cites W2811004238 @default.
• W3108594910 cites W2965540452 @default.
• W3108594910 cites W3004897282 @default.
• W3108594910 cites W3007738788 @default.
• W3108594910 cites W4233465729 @default.
• W3108594910 doi "https://doi.org/10.1093/rheumatology/keaa699" @default.
• W3108594910 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33253372" @default.
• W3108594910 hasPublicationYear "2020" @default.
• W3108594910 type Work @default.
• W3108594910 sameAs 3108594910 @default.
• W3108594910 citedByCount "24" @default.
• W3108594910 countsByYear W31085949102021 @default.
• W3108594910 countsByYear W31085949102022 @default.
• W3108594910 countsByYear W31085949102023 @default.
• W3108594910 crossrefType "journal-article" @default.
• W3108594910 hasAuthorship W3108594910A5007888588 @default.
• W3108594910 hasAuthorship W3108594910A5028156038 @default.
• W3108594910 hasAuthorship W3108594910A5032983734 @default.
• W3108594910 hasAuthorship W3108594910A5067715072 @default.
• W3108594910 hasAuthorship W3108594910A5070674274 @default.
• W3108594910 hasConcept C120665830 @default.
• W3108594910 hasConcept C121332964 @default.
• W3108594910 hasConcept C126322002 @default.
• W3108594910 hasConcept C207103383 @default.
• W3108594910 hasConcept C2776015282 @default.
• W3108594910 hasConcept C2777914695 @default.
• W3108594910 hasConcept C2778384902 @default.
• W3108594910 hasConcept C2779134260 @default.
• W3108594910 hasConcept C2908647359 @default.
• W3108594910 hasConcept C44249647 @default.
• W3108594910 hasConcept C50382708 @default.
• W3108594910 hasConcept C61511704 @default.
• W3108594910 hasConcept C71924100 @default.
• W3108594910 hasConcept C72563966 @default.
• W3108594910 hasConcept C99454951 @default.
• W3108594910 hasConceptScore W3108594910C120665830 @default.
• W3108594910 hasConceptScore W3108594910C121332964 @default.
• W3108594910 hasConceptScore W3108594910C126322002 @default.
• W3108594910 hasConceptScore W3108594910C207103383 @default.
• W3108594910 hasConceptScore W3108594910C2776015282 @default.
• W3108594910 hasConceptScore W3108594910C2777914695 @default.
• W3108594910 hasConceptScore W3108594910C2778384902 @default.
• W3108594910 hasConceptScore W3108594910C2779134260 @default.
• W3108594910 hasConceptScore W3108594910C2908647359 @default.
• W3108594910 hasConceptScore W3108594910C44249647 @default.
• W3108594910 hasConceptScore W3108594910C50382708 @default.
• W3108594910 hasConceptScore W3108594910C61511704 @default.
• W3108594910 hasConceptScore W3108594910C71924100 @default.
• W3108594910 hasConceptScore W3108594910C72563966 @default.
• W3108594910 hasConceptScore W3108594910C99454951 @default.
• W3108594910 hasFunder F4320322581 @default.
• W3108594910 hasIssue "6" @default.
• W3108594910 hasLocation W31085949101 @default.
• W3108594910 hasOpenAccess W3108594910 @default.
• W3108594910 hasPrimaryLocation W31085949101 @default.

• next