FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3108642835> ?p ?o ?g. }

• W3108642835 abstract "Abstract Introduction Balloon pulmonary angioplasty (BPA) has been reported as an effective and safe treatment for patients with chronic thromboembolic pulmonary hypertension (CTEPH). However, its safety and efficacy in elderly patients remains unknown. Purpose We investigated the effect of BPA on hemodynamics and respiratory parameters, functional capacity, and short- and long-term outcome in elderly patients. Methods From November 2012 to May 2018, 141 consecutive CTEPH patients who underwent BPA in a single university hospital were enrolled (age: 65 [54.5–74] years old, WHO functional class [WHO-FC] II/III/IV; 35/96/10). Patients were divided into two groups according to the age; elderly (≥75 years, N=32) and young groups (&lt;75 years, N=109). Hemodynamics (right-sided heart catheterization), biomarkers (brain natriuretic peptide), respiratory function (spirometry and diffusion capacity measurement), and functional capacity (6-minute walk distance [6MWD] and WHO-FC) were evaluated at baseline and 1-year post BPA. Procedure-related complications (in hospital death, use of percutaneous cardiopulmonary support [PCPS], and pulmonary injury) and all cause death during the follow up period were also assessed. Results At baseline, although elderly group had less severe hemodynamics (mPAP: 33.1±6.7 vs 39.0±11.8 mmHg, p&lt;0.05), they had poor exercise capacity and reduced pulmonary diffusion capacity, compared with young group (6MWD: 264.6±101.3 vs 369.7±105.2 m, %DLco: 42.0±12.0 vs 50.2±12.7%, all p&lt;0.05). BPA improved hemodynamics, biomarkers, exercise capacity, and pulmonary diffusion capacity in both elderly and young groups (all p&lt;0.05). There was no in-hospital death or use of PCPS in both groups, although the incidence of pulmonary injury was higher in elderly group (14.3% vs 5.3%, p&lt;0.01). Under the normalized hemodynamics 1-year after BPA in both groups, exercise capacity and pulmonary diffusion capacity were worse in the elderly group than young groups (p&lt;0.01). The incidence of all-cause death in the follow up period was higher in elderly group, all of which were due to non-pulmonary hypertension (PH)-related death (p&lt;0.01). Conclusion BPA was effective in improving hemodynamics and respiratory parameters and functional capacity, in associated with no critical complication, regardless of the age. Elderly patients who were treated with BPA were associated with higher incidence of non-PH-related death. Changes of mean PAP in the two groups Funding Acknowledgement Type of funding source: None" @default.
• W3108642835 created "2020-12-07" @default.
• W3108642835 creator A5012511455 @default.
• W3108642835 creator A5026952613 @default.
• W3108642835 creator A5032391470 @default.
• W3108642835 creator A5039812688 @default.
• W3108642835 creator A5050286894 @default.
• W3108642835 creator A5069453818 @default.
• W3108642835 creator A5074124307 @default.
• W3108642835 creator A5080486400 @default.
• W3108642835 creator A5083083314 @default.
• W3108642835 creator A5088625667 @default.
• W3108642835 date "2020-11-01" @default.
• W3108642835 modified "2023-09-23" @default.
• W3108642835 title "Efficacy and outcomes of balloon pulmonary angioplasty in elderly vs non-elderly chronic thromboembolic pulmonary hypertension patients" @default.
• W3108642835 doi "https://doi.org/10.1093/ehjci/ehaa946.2263" @default.
• W3108642835 hasPublicationYear "2020" @default.
• W3108642835 type Work @default.
• W3108642835 sameAs 3108642835 @default.
• W3108642835 citedByCount "0" @default.
• W3108642835 crossrefType "journal-article" @default.
• W3108642835 hasAuthorship W3108642835A5012511455 @default.
• W3108642835 hasAuthorship W3108642835A5026952613 @default.
• W3108642835 hasAuthorship W3108642835A5032391470 @default.
• W3108642835 hasAuthorship W3108642835A5039812688 @default.
• W3108642835 hasAuthorship W3108642835A5050286894 @default.
• W3108642835 hasAuthorship W3108642835A5069453818 @default.
• W3108642835 hasAuthorship W3108642835A5074124307 @default.
• W3108642835 hasAuthorship W3108642835A5080486400 @default.
• W3108642835 hasAuthorship W3108642835A5083083314 @default.
• W3108642835 hasAuthorship W3108642835A5088625667 @default.
• W3108642835 hasConcept C126322002 @default.
• W3108642835 hasConcept C16020263 @default.
• W3108642835 hasConcept C164705383 @default.
• W3108642835 hasConcept C165637977 @default.
• W3108642835 hasConcept C178853913 @default.
• W3108642835 hasConcept C2776042228 @default.
• W3108642835 hasConcept C2777714996 @default.
• W3108642835 hasConcept C2780326628 @default.
• W3108642835 hasConcept C2780333948 @default.
• W3108642835 hasConcept C2780930700 @default.
• W3108642835 hasConcept C3018587741 @default.
• W3108642835 hasConcept C71924100 @default.
• W3108642835 hasConcept C75603125 @default.
• W3108642835 hasConceptScore W3108642835C126322002 @default.
• W3108642835 hasConceptScore W3108642835C16020263 @default.
• W3108642835 hasConceptScore W3108642835C164705383 @default.
• W3108642835 hasConceptScore W3108642835C165637977 @default.
• W3108642835 hasConceptScore W3108642835C178853913 @default.
• W3108642835 hasConceptScore W3108642835C2776042228 @default.
• W3108642835 hasConceptScore W3108642835C2777714996 @default.
• W3108642835 hasConceptScore W3108642835C2780326628 @default.
• W3108642835 hasConceptScore W3108642835C2780333948 @default.
• W3108642835 hasConceptScore W3108642835C2780930700 @default.
• W3108642835 hasConceptScore W3108642835C3018587741 @default.
• W3108642835 hasConceptScore W3108642835C71924100 @default.
• W3108642835 hasConceptScore W3108642835C75603125 @default.
• W3108642835 hasLocation W31086428351 @default.
• W3108642835 hasOpenAccess W3108642835 @default.
• W3108642835 hasPrimaryLocation W31086428351 @default.
• W3108642835 hasRelatedWork W11455767 @default.
• W3108642835 hasRelatedWork W13249562 @default.
• W3108642835 hasRelatedWork W13679872 @default.
• W3108642835 hasRelatedWork W15293244 @default.
• W3108642835 hasRelatedWork W15334259 @default.
• W3108642835 hasRelatedWork W19457758 @default.
• W3108642835 hasRelatedWork W4703656 @default.
• W3108642835 hasRelatedWork W5810732 @default.
• W3108642835 hasRelatedWork W6229200 @default.
• W3108642835 hasRelatedWork W6649280 @default.
• W3108642835 isParatext "false" @default.
• W3108642835 isRetracted "false" @default.
• W3108642835 magId "3108642835" @default.
• W3108642835 workType "article" @default.