FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3108725030> ?p ?o ?g. }

• W3108725030 abstract "Abstract Synergistic effects of bacteria on viral stability and transmission are widely documented but remain unclear in the context of SARS-CoV-2. We collected 972 samples from hospitalized patients with coronavirus disease 2019 (COVID-19), their health care providers, and hospital surfaces before, during, and after admission. We screened for SARS-CoV-2 using RT-qPCR, characterized microbial communities using 16S rRNA gene amplicon sequencing, and contextualized the massive microbial diversity in this dataset through meta-analysis of over 20,000 samples. Sixteen percent of surfaces from COVID-19 patient rooms were positive, with the highest prevalence in floor samples next to patient beds (39%) and directly outside their rooms (29%). Although bed rail samples increasingly resembled the patient microbiome over time, SARS-CoV-2 was detected less there (11%). Despite viral surface contamination in almost all patient rooms, no health care workers contracted the disease, suggesting that personal protective equipment was effective in preventing transmissions. SARS-CoV-2 positive samples had higher bacterial phylogenetic diversity across human and surface samples, and higher biomass in floor samples. 16S microbial community profiles allowed for high SARS-CoV-2 classifier accuracy in not only nares, but also forehead, stool, and floor samples. Across distinct microbial profiles, a single amplicon sequence variant from the genus Rothia was highly predictive of SARS-CoV-2 across sample types and had higher prevalence in positive surface and human samples, even compared to samples from patients in another intensive care unit prior to the COVID-19 pandemic. These results suggest that bacterial communities may contribute to viral prevalence both in the host and hospital environment. One Sentence Summary Microbial classifier highlights specific taxa predictive of SARS-CoV-2 prevalence across diverse microbial niches in a COVID-19 hospital unit." @default.
• W3108725030 created "2020-12-07" @default.
• W3108725030 creator A5000137125 @default.
• W3108725030 creator A5002373415 @default.
• W3108725030 creator A5004663363 @default.
• W3108725030 creator A5005731611 @default.
• W3108725030 creator A5009197283 @default.
• W3108725030 creator A5009540046 @default.
• W3108725030 creator A5013598446 @default.
• W3108725030 creator A5015619159 @default.
• W3108725030 creator A5017354836 @default.
• W3108725030 creator A5021412772 @default.
• W3108725030 creator A5022020022 @default.
• W3108725030 creator A5024143614 @default.
• W3108725030 creator A5025497346 @default.
• W3108725030 creator A5033881627 @default.
• W3108725030 creator A5041994817 @default.
• W3108725030 creator A5043161270 @default.
• W3108725030 creator A5043464127 @default.
• W3108725030 creator A5046787865 @default.
• W3108725030 creator A5054652878 @default.
• W3108725030 creator A5057060580 @default.
• W3108725030 creator A5058082063 @default.
• W3108725030 creator A5062335770 @default.
• W3108725030 creator A5066665482 @default.
• W3108725030 creator A5067810319 @default.
• W3108725030 creator A5068472617 @default.
• W3108725030 creator A5069508614 @default.
• W3108725030 creator A5073381107 @default.
• W3108725030 creator A5077137639 @default.
• W3108725030 creator A5078091883 @default.
• W3108725030 creator A5078714663 @default.
• W3108725030 creator A5082592240 @default.
• W3108725030 creator A5085462551 @default.
• W3108725030 creator A5086398242 @default.
• W3108725030 creator A5087040149 @default.
• W3108725030 creator A5087126302 @default.
• W3108725030 date "2020-11-22" @default.
• W3108725030 modified "2023-09-30" @default.
• W3108725030 title "Microbial context predicts SARS-CoV-2 prevalence in patients and the hospital built environment" @default.
• W3108725030 cites W1831050183 @default.
• W3108725030 cites W1881563271 @default.
• W3108725030 cites W1969430209 @default.
• W3108725030 cites W1992223383 @default.
• W3108725030 cites W1995362868 @default.
• W3108725030 cites W1995637762 @default.
• W3108725030 cites W2016254764 @default.
• W3108725030 cites W2038838030 @default.
• W3108725030 cites W2054407804 @default.
• W3108725030 cites W2058530259 @default.
• W3108725030 cites W2117522399 @default.
• W3108725030 cites W2153198746 @default.
• W3108725030 cites W2160187521 @default.
• W3108725030 cites W2278924483 @default.
• W3108725030 cites W2342540743 @default.
• W3108725030 cites W2347104163 @default.
• W3108725030 cites W2510962849 @default.
• W3108725030 cites W2593591803 @default.
• W3108725030 cites W2603489941 @default.
• W3108725030 cites W2620149559 @default.
• W3108725030 cites W2766358903 @default.
• W3108725030 cites W2772780635 @default.
• W3108725030 cites W2776528073 @default.
• W3108725030 cites W2794083477 @default.
• W3108725030 cites W2794407684 @default.
• W3108725030 cites W2800690051 @default.
• W3108725030 cites W2828373141 @default.
• W3108725030 cites W2888005221 @default.
• W3108725030 cites W2888547803 @default.
• W3108725030 cites W2892206041 @default.
• W3108725030 cites W2893082618 @default.
• W3108725030 cites W2896638680 @default.
• W3108725030 cites W2900393174 @default.
• W3108725030 cites W2914348147 @default.
• W3108725030 cites W2917826539 @default.
• W3108725030 cites W2945285105 @default.
• W3108725030 cites W2946804179 @default.
• W3108725030 cites W2950245396 @default.
• W3108725030 cites W2952000480 @default.
• W3108725030 cites W2963276645 @default.
• W3108725030 cites W2983462094 @default.
• W3108725030 cites W3001195213 @default.
• W3108725030 cites W3003431421 @default.
• W3108725030 cites W3008443627 @default.
• W3108725030 cites W3010409396 @default.
• W3108725030 cites W3012099172 @default.
• W3108725030 cites W3012415734 @default.
• W3108725030 cites W3015839776 @default.
• W3108725030 cites W3016207602 @default.
• W3108725030 cites W3018107690 @default.
• W3108725030 cites W3021347665 @default.
• W3108725030 cites W3021581049 @default.
• W3108725030 cites W3021696027 @default.
• W3108725030 cites W3025322654 @default.
• W3108725030 cites W3025871232 @default.
• W3108725030 cites W3030968929 @default.
• W3108725030 cites W3033735761 @default.
• W3108725030 cites W3038406893 @default.
• W3108725030 cites W3042086946 @default.
• W3108725030 cites W3043000797 @default.

• next