Matches in SemOpenAlex for { <https://semopenalex.org/work/W3108797164> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W3108797164 endingPage "1190" @default.
- W3108797164 startingPage "1190" @default.
- W3108797164 abstract "Sildenafil, tadalafil, and vardenafil are phosphodiesterase type 5 enzyme (PDE-5) inhibitors used for the treatment of male erectile dysfunction. This present study aims to investigate 55 herbal products indicated for men’s sexual health from the Malaysian market for adulteration of PDE-5 inhibitors and analogues. The screening and identification of 20 PDE-5 inhibitors and analogues in herbal products of various forms (powder, capsules, tablets, and pastels) were conducted using gas chromatography–electron impact-mass spectrometer (GC-EI-MS). The analysis has shown that 19 herbal products were adulterated with PDE-5 inhibitors and analogues. Unique ion fragmentations and the presence of molecular ion serve as potential markers, and the limit of detection (LOD) was 0.1-5.0 µg/g. Ten PDE-5 inhibitors and analogues were randomly selected and successfully validated for simultaneous quantification, whereby the limit of quantitation (LOQ) was 5.0–50.0 µg/g with recoveries at 86.1-118.9%. The developed method of GC-EI-MS was shown to be simple, throughput, economical and had sufficient sensitivity to screen, identify and quantify PDE-5 inhibitors and analogues in herbal matrices." @default.
- W3108797164 created "2020-12-07" @default.
- W3108797164 creator A5000310093 @default.
- W3108797164 creator A5021229324 @default.
- W3108797164 creator A5035767834 @default.
- W3108797164 creator A5051196526 @default.
- W3108797164 creator A5073703362 @default.
- W3108797164 date "2020-12-01" @default.
- W3108797164 modified "2023-09-27" @default.
- W3108797164 title "Determination of Phosphodiesterase Type 5 Enzyme (PDE-5) Inhibitors and Analogues as Adulterants in Selected Herbal Products using Gas Chromatography–Electron Impact-Mass Spectrometer (GC-EI-MS)" @default.
- W3108797164 cites W1571624993 @default.
- W3108797164 cites W1971812149 @default.
- W3108797164 cites W1974904275 @default.
- W3108797164 cites W1981126255 @default.
- W3108797164 cites W1994767565 @default.
- W3108797164 cites W1996142629 @default.
- W3108797164 cites W2037689080 @default.
- W3108797164 cites W2070557861 @default.
- W3108797164 cites W2079750766 @default.
- W3108797164 cites W2086585909 @default.
- W3108797164 cites W2119716443 @default.
- W3108797164 cites W2521607953 @default.
- W3108797164 cites W2563156013 @default.
- W3108797164 cites W2624293696 @default.
- W3108797164 cites W2917644998 @default.
- W3108797164 cites W851149693 @default.
- W3108797164 doi "https://doi.org/10.21123/bsj.2020.17.4.1190" @default.
- W3108797164 hasPublicationYear "2020" @default.
- W3108797164 type Work @default.
- W3108797164 sameAs 3108797164 @default.
- W3108797164 citedByCount "1" @default.
- W3108797164 countsByYear W31087971642022 @default.
- W3108797164 crossrefType "journal-article" @default.
- W3108797164 hasAuthorship W3108797164A5000310093 @default.
- W3108797164 hasAuthorship W3108797164A5021229324 @default.
- W3108797164 hasAuthorship W3108797164A5035767834 @default.
- W3108797164 hasAuthorship W3108797164A5051196526 @default.
- W3108797164 hasAuthorship W3108797164A5073703362 @default.
- W3108797164 hasBestOaLocation W31087971641 @default.
- W3108797164 hasConcept C119128265 @default.
- W3108797164 hasConcept C123460561 @default.
- W3108797164 hasConcept C141071460 @default.
- W3108797164 hasConcept C162356407 @default.
- W3108797164 hasConcept C181199279 @default.
- W3108797164 hasConcept C185592680 @default.
- W3108797164 hasConcept C205345274 @default.
- W3108797164 hasConcept C2778822586 @default.
- W3108797164 hasConcept C2779929075 @default.
- W3108797164 hasConcept C2780816001 @default.
- W3108797164 hasConcept C43617362 @default.
- W3108797164 hasConcept C55493867 @default.
- W3108797164 hasConcept C62826618 @default.
- W3108797164 hasConcept C71924100 @default.
- W3108797164 hasConcept C74534348 @default.
- W3108797164 hasConceptScore W3108797164C119128265 @default.
- W3108797164 hasConceptScore W3108797164C123460561 @default.
- W3108797164 hasConceptScore W3108797164C141071460 @default.
- W3108797164 hasConceptScore W3108797164C162356407 @default.
- W3108797164 hasConceptScore W3108797164C181199279 @default.
- W3108797164 hasConceptScore W3108797164C185592680 @default.
- W3108797164 hasConceptScore W3108797164C205345274 @default.
- W3108797164 hasConceptScore W3108797164C2778822586 @default.
- W3108797164 hasConceptScore W3108797164C2779929075 @default.
- W3108797164 hasConceptScore W3108797164C2780816001 @default.
- W3108797164 hasConceptScore W3108797164C43617362 @default.
- W3108797164 hasConceptScore W3108797164C55493867 @default.
- W3108797164 hasConceptScore W3108797164C62826618 @default.
- W3108797164 hasConceptScore W3108797164C71924100 @default.
- W3108797164 hasConceptScore W3108797164C74534348 @default.
- W3108797164 hasIssue "4" @default.
- W3108797164 hasLocation W31087971641 @default.
- W3108797164 hasLocation W31087971642 @default.
- W3108797164 hasOpenAccess W3108797164 @default.
- W3108797164 hasPrimaryLocation W31087971641 @default.
- W3108797164 hasRelatedWork W1500970230 @default.
- W3108797164 hasRelatedWork W2022738955 @default.
- W3108797164 hasRelatedWork W2031250811 @default.
- W3108797164 hasRelatedWork W2042758222 @default.
- W3108797164 hasRelatedWork W2079838599 @default.
- W3108797164 hasRelatedWork W2085095071 @default.
- W3108797164 hasRelatedWork W2399779522 @default.
- W3108797164 hasRelatedWork W2466143905 @default.
- W3108797164 hasRelatedWork W2601322913 @default.
- W3108797164 hasRelatedWork W4308898149 @default.
- W3108797164 hasVolume "17" @default.
- W3108797164 isParatext "false" @default.
- W3108797164 isRetracted "false" @default.
- W3108797164 magId "3108797164" @default.
- W3108797164 workType "article" @default.