FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3108851982> ?p ?o ?g. }

• W3108851982 endingPage "853" @default.
• W3108851982 startingPage "850" @default.
• W3108851982 abstract "Abstract Naltrexone/bupropion (NB) is a US Food and Drug Administration‐approved antiobesity medication. Clinical trials have shown variable weight loss, with responders and non‐responders. NB is believed to act on central dopaminergic pathways to suppress appetite. The Taq1A polymorphism near DRD2 (rs1800497) is associated with the density of striatal dopamine D2 receptors, with individuals carrying the A allele (AA or AG; termed A1+) having 30%‐40% fewer dopamine binding sites than those who do not carry the A allele (GG; termed A1‐). We performed a pilot study to assess the association of the rs1800497 ANKK1 c.2137G > A (p.Glu713Lys) variant with weight loss with NB treatment in 33 subjects. Mean (SD) weight loss was 5.9% (3.2%) for the A1+ genotype group (n = 15) and 4.2% (4.2%) for the A1‐ genotype group (n = 18). The mean weight loss for the A1+ genotype group was significantly greater than the predefined clinically significant 4% weight‐loss target (one‐sample t‐test, P = .035), whereas the mean weight loss for the A1‐ genotype group was not ( P = .85). Individuals with the A1+ genotype appear to respond better to NB than A1‐ individuals." @default.
• W3108851982 created "2020-12-07" @default.
• W3108851982 creator A5014313479 @default.
• W3108851982 creator A5018722278 @default.
• W3108851982 creator A5024233450 @default.
• W3108851982 creator A5035923356 @default.
• W3108851982 creator A5049738260 @default.
• W3108851982 creator A5058342195 @default.
• W3108851982 creator A5080365677 @default.
• W3108851982 creator A5084469317 @default.
• W3108851982 date "2021-01-08" @default.
• W3108851982 modified "2023-10-16" @default.
• W3108851982 title "Weight‐loss response to naltrexone/bupropion is modulated by the <scp>Taq1A</scp> genetic variant near <scp><i>DRD2</i></scp> (<scp>rs1800497</scp>): A pilot study" @default.
• W3108851982 cites W1964979617 @default.
• W3108851982 cites W1994905981 @default.
• W3108851982 cites W1999724180 @default.
• W3108851982 cites W2032890518 @default.
• W3108851982 cites W2092703117 @default.
• W3108851982 cites W2093792267 @default.
• W3108851982 cites W2100882412 @default.
• W3108851982 cites W2110438413 @default.
• W3108851982 cites W2138419072 @default.
• W3108851982 cites W2140287802 @default.
• W3108851982 cites W2144589456 @default.
• W3108851982 cites W2155601015 @default.
• W3108851982 cites W2158287537 @default.
• W3108851982 cites W2159388107 @default.
• W3108851982 cites W2401750321 @default.
• W3108851982 cites W2470467325 @default.
• W3108851982 cites W2966481576 @default.
• W3108851982 cites W2972610850 @default.
• W3108851982 cites W3010682058 @default.
• W3108851982 doi "https://doi.org/10.1111/dom.14267" @default.
• W3108851982 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8106923" @default.
• W3108851982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33236485" @default.
• W3108851982 hasPublicationYear "2021" @default.
• W3108851982 type Work @default.
• W3108851982 sameAs 3108851982 @default.
• W3108851982 citedByCount "7" @default.
• W3108851982 countsByYear W31088519822021 @default.
• W3108851982 countsByYear W31088519822022 @default.
• W3108851982 countsByYear W31088519822023 @default.
• W3108851982 crossrefType "journal-article" @default.
• W3108851982 hasAuthorship W3108851982A5014313479 @default.
• W3108851982 hasAuthorship W3108851982A5018722278 @default.
• W3108851982 hasAuthorship W3108851982A5024233450 @default.
• W3108851982 hasAuthorship W3108851982A5035923356 @default.
• W3108851982 hasAuthorship W3108851982A5049738260 @default.
• W3108851982 hasAuthorship W3108851982A5058342195 @default.
• W3108851982 hasAuthorship W3108851982A5080365677 @default.
• W3108851982 hasAuthorship W3108851982A5084469317 @default.
• W3108851982 hasBestOaLocation W31088519822 @default.
• W3108851982 hasConcept C104317684 @default.
• W3108851982 hasConcept C126322002 @default.
• W3108851982 hasConcept C134018914 @default.
• W3108851982 hasConcept C135763542 @default.
• W3108851982 hasConcept C142724271 @default.
• W3108851982 hasConcept C170493617 @default.
• W3108851982 hasConcept C180754005 @default.
• W3108851982 hasConcept C2776885963 @default.
• W3108851982 hasConcept C2777843972 @default.
• W3108851982 hasConcept C2777972943 @default.
• W3108851982 hasConcept C2779908668 @default.
• W3108851982 hasConcept C511355011 @default.
• W3108851982 hasConcept C54355233 @default.
• W3108851982 hasConcept C544821477 @default.
• W3108851982 hasConcept C71924100 @default.
• W3108851982 hasConcept C86803240 @default.
• W3108851982 hasConcept C98274493 @default.
• W3108851982 hasConceptScore W3108851982C104317684 @default.
• W3108851982 hasConceptScore W3108851982C126322002 @default.
• W3108851982 hasConceptScore W3108851982C134018914 @default.
• W3108851982 hasConceptScore W3108851982C135763542 @default.
• W3108851982 hasConceptScore W3108851982C142724271 @default.
• W3108851982 hasConceptScore W3108851982C170493617 @default.
• W3108851982 hasConceptScore W3108851982C180754005 @default.
• W3108851982 hasConceptScore W3108851982C2776885963 @default.
• W3108851982 hasConceptScore W3108851982C2777843972 @default.
• W3108851982 hasConceptScore W3108851982C2777972943 @default.
• W3108851982 hasConceptScore W3108851982C2779908668 @default.
• W3108851982 hasConceptScore W3108851982C511355011 @default.
• W3108851982 hasConceptScore W3108851982C54355233 @default.
• W3108851982 hasConceptScore W3108851982C544821477 @default.
• W3108851982 hasConceptScore W3108851982C71924100 @default.
• W3108851982 hasConceptScore W3108851982C86803240 @default.
• W3108851982 hasConceptScore W3108851982C98274493 @default.
• W3108851982 hasIssue "3" @default.
• W3108851982 hasLocation W31088519821 @default.
• W3108851982 hasLocation W31088519822 @default.
• W3108851982 hasLocation W31088519823 @default.
• W3108851982 hasOpenAccess W3108851982 @default.
• W3108851982 hasPrimaryLocation W31088519821 @default.
• W3108851982 hasRelatedWork W1567113729 @default.
• W3108851982 hasRelatedWork W1997066747 @default.
• W3108851982 hasRelatedWork W2031087264 @default.
• W3108851982 hasRelatedWork W205364041 @default.
• W3108851982 hasRelatedWork W2063044913 @default.
• W3108851982 hasRelatedWork W2064449076 @default.

• next