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- W3108989578 abstract "Virotherapy, a strategy to use live viruses as therapeutics, is a relatively novel field in the treatment of cancer. With the advancements in molecular biology and virology, there has been a huge increase in research on cancer virotherapy. For the treatment of cancer, viruses could be used either as vectors in gene therapy or as oncolytic agents. A variety of viruses have been studied for their potential usage in gene therapy or oncolytic therapy. In this review, we discuss virotherapy with a special focus on breast cancer. Breast cancer is the most common cancer and the leading cause of cancer-related deaths in women worldwide. Current treatments are insufficient to cure metastatic breast cancer and are often associated with severe side effects that further deteriorates patients' quality of life. Therefore, novel therapeutic approaches such as virotherapy need to be developed for the treatment of breast cancer. Here we summarize the current treatments for breast cancer and the potential use of virotherapy in the treatment of the disease. Furthermore, we discuss the use of oncolytic viruses as immunotherapeutics and the rational combination of oncolytic viruses with other therapeutics for optimal treatment of breast cancer. Finally, we outline the progress made in virotherapy for breast cancer and the shortcomings that need to be addressed for this novel therapy to move to the clinic for better treatment of breast cancer." @default.
- W3108989578 created "2020-12-07" @default.
- W3108989578 creator A5005824918 @default.
- W3108989578 creator A5067353931 @default.
- W3108989578 date "2020-12-02" @default.
- W3108989578 modified "2023-10-06" @default.
- W3108989578 title "Viroimmunotherapy for breast cancer: promises, problems and future directions" @default.
- W3108989578 cites W1501808502 @default.
- W3108989578 cites W1699527811 @default.
- W3108989578 cites W1818000388 @default.
- W3108989578 cites W1842857082 @default.
- W3108989578 cites W1924256095 @default.
- W3108989578 cites W1961026612 @default.
- W3108989578 cites W1965497380 @default.
- W3108989578 cites W1966063402 @default.
- W3108989578 cites W1967262248 @default.
- W3108989578 cites W1972887015 @default.
- W3108989578 cites W1973901905 @default.
- W3108989578 cites W1983964714 @default.
- W3108989578 cites W1986483553 @default.
- W3108989578 cites W1986993149 @default.
- W3108989578 cites W1987468883 @default.
- W3108989578 cites W1992749856 @default.
- W3108989578 cites W1997912140 @default.
- W3108989578 cites W2012150814 @default.
- W3108989578 cites W2016626787 @default.
- W3108989578 cites W2021476941 @default.
- W3108989578 cites W2022199544 @default.
- W3108989578 cites W2029735288 @default.
- W3108989578 cites W2029965175 @default.
- W3108989578 cites W2038840324 @default.
- W3108989578 cites W2040512792 @default.
- W3108989578 cites W2044702943 @default.
- W3108989578 cites W2057782225 @default.
- W3108989578 cites W2065360869 @default.
- W3108989578 cites W2073961237 @default.
- W3108989578 cites W2087984814 @default.
- W3108989578 cites W2090732350 @default.
- W3108989578 cites W2092601545 @default.
- W3108989578 cites W2093921289 @default.
- W3108989578 cites W2096283457 @default.
- W3108989578 cites W2097255042 @default.
- W3108989578 cites W2098775844 @default.
- W3108989578 cites W2102142353 @default.
- W3108989578 cites W2112228300 @default.
- W3108989578 cites W2112979829 @default.
- W3108989578 cites W2113794558 @default.
- W3108989578 cites W2117692326 @default.
- W3108989578 cites W2120426523 @default.
- W3108989578 cites W2120482363 @default.
- W3108989578 cites W2121854651 @default.
- W3108989578 cites W2124221114 @default.
- W3108989578 cites W2125051098 @default.
- W3108989578 cites W2125382661 @default.
- W3108989578 cites W2128237332 @default.
- W3108989578 cites W2128892990 @default.
- W3108989578 cites W2129253249 @default.
- W3108989578 cites W2130872475 @default.
- W3108989578 cites W2131994307 @default.
- W3108989578 cites W2143207956 @default.
- W3108989578 cites W2156950231 @default.
- W3108989578 cites W2157285286 @default.
- W3108989578 cites W2160335399 @default.
- W3108989578 cites W2161397941 @default.
- W3108989578 cites W2161770015 @default.
- W3108989578 cites W2166261585 @default.
- W3108989578 cites W2166838688 @default.
- W3108989578 cites W2167284803 @default.
- W3108989578 cites W2183585286 @default.
- W3108989578 cites W2259802687 @default.
- W3108989578 cites W2292927556 @default.
- W3108989578 cites W2315436341 @default.
- W3108989578 cites W2320304105 @default.
- W3108989578 cites W2324106738 @default.
- W3108989578 cites W2331948039 @default.
- W3108989578 cites W2345984910 @default.
- W3108989578 cites W2476943242 @default.
- W3108989578 cites W2510344434 @default.
- W3108989578 cites W2560367415 @default.
- W3108989578 cites W2602691345 @default.
- W3108989578 cites W2615468880 @default.
- W3108989578 cites W2618834187 @default.
- W3108989578 cites W2750781282 @default.
- W3108989578 cites W2760883434 @default.
- W3108989578 cites W2778445562 @default.
- W3108989578 cites W2781905683 @default.
- W3108989578 cites W2792291600 @default.
- W3108989578 cites W2792540082 @default.
- W3108989578 cites W2795851363 @default.
- W3108989578 cites W2807944903 @default.
- W3108989578 cites W2831112273 @default.
- W3108989578 cites W2889646458 @default.
- W3108989578 cites W2904883738 @default.
- W3108989578 cites W2919987102 @default.
- W3108989578 cites W2921074918 @default.
- W3108989578 cites W2961709931 @default.
- W3108989578 cites W2972770174 @default.
- W3108989578 cites W2976242996 @default.