FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109020512> ?p ?o ?g. }

• W3109020512 endingPage "3607" @default.
• W3109020512 startingPage "3607" @default.
• W3109020512 abstract "In inflammatory bowel disease (IBD), experimental models have proven to be important tools for evaluating potential therapeutic agents and for investigating the mechanisms of pathogenesis. Oxidative stress and the immune response have been associated with acetic acid (AA)-induced ulcerative colitis (UC). Our study aimed to evaluate, for the first time, the ability of a spore-based probiotic and an amino acid and immunoglobulin supplement in reducing tissue damage and inflammatory responses in an experimental animal model of UC. Forty-two Wistar rats were divided into six groups, receiving 1% carboxymethylcellulose, 4% AA, MegaSporeBiotic™ (MSB; 1 × 109 colony forming units/day) and MegaMucosa™ (MM; 70 mg/100 g/day). Pretreatment with MSB or MM alone and in combination significantly lowered inflammation and reduced damage to the colonic mucosa. Pretreatment with these agents resulted in levels of proinflammatory cytokines, vascular tight junction proteins, and measures of oxidative stress similar to those reported for methylprednisolone, one of the first-line therapies for moderate to severe activity of UC. The protection was further confirmed by histologic analysis of the colon tissue. In conclusion, pretreatment with probiotic spore-forming Bacillus strains and a supplement of amino acids in combination with immunoglobulins exhibited anti-inflammatory and antioxidant effects in an AA-induced rat model of UC." @default.
• W3109020512 created "2020-12-07" @default.
• W3109020512 creator A5007070631 @default.
• W3109020512 creator A5007555709 @default.
• W3109020512 creator A5013459788 @default.
• W3109020512 creator A5015882639 @default.
• W3109020512 creator A5021186201 @default.
• W3109020512 creator A5061401105 @default.
• W3109020512 creator A5062034700 @default.
• W3109020512 creator A5068349878 @default.
• W3109020512 creator A5072416977 @default.
• W3109020512 date "2020-11-24" @default.
• W3109020512 modified "2023-10-17" @default.
• W3109020512 title "Probiotic Bacillus Spores Together with Amino Acids and Immunoglobulins Exert Protective Effects on a Rat Model of Ulcerative Colitis" @default.
• W3109020512 cites W1548328591 @default.
• W3109020512 cites W1550488867 @default.
• W3109020512 cites W184167452 @default.
• W3109020512 cites W191793640 @default.
• W3109020512 cites W1997103341 @default.
• W3109020512 cites W1997889028 @default.
• W3109020512 cites W2004274286 @default.
• W3109020512 cites W2006632373 @default.
• W3109020512 cites W2014785793 @default.
• W3109020512 cites W2016663225 @default.
• W3109020512 cites W2029726557 @default.
• W3109020512 cites W2036682827 @default.
• W3109020512 cites W2040206306 @default.
• W3109020512 cites W2062011685 @default.
• W3109020512 cites W2070748913 @default.
• W3109020512 cites W2074315483 @default.
• W3109020512 cites W2082138080 @default.
• W3109020512 cites W2097875133 @default.
• W3109020512 cites W2108927902 @default.
• W3109020512 cites W2112489212 @default.
• W3109020512 cites W2116318925 @default.
• W3109020512 cites W2119236196 @default.
• W3109020512 cites W2132984860 @default.
• W3109020512 cites W2136269756 @default.
• W3109020512 cites W2137777492 @default.
• W3109020512 cites W2141800155 @default.
• W3109020512 cites W2148093196 @default.
• W3109020512 cites W2151280055 @default.
• W3109020512 cites W2160325274 @default.
• W3109020512 cites W2162974883 @default.
• W3109020512 cites W2306466871 @default.
• W3109020512 cites W2313687783 @default.
• W3109020512 cites W2318905720 @default.
• W3109020512 cites W2347014415 @default.
• W3109020512 cites W2474143150 @default.
• W3109020512 cites W2591923276 @default.
• W3109020512 cites W2593033949 @default.
• W3109020512 cites W2599036809 @default.
• W3109020512 cites W2603204315 @default.
• W3109020512 cites W2626195186 @default.
• W3109020512 cites W2739502069 @default.
• W3109020512 cites W2743604784 @default.
• W3109020512 cites W2746054219 @default.
• W3109020512 cites W2757080426 @default.
• W3109020512 cites W2763369925 @default.
• W3109020512 cites W2885492105 @default.
• W3109020512 cites W2891027798 @default.
• W3109020512 cites W2901417922 @default.
• W3109020512 cites W2905543613 @default.
• W3109020512 cites W2906783828 @default.
• W3109020512 cites W2919677611 @default.
• W3109020512 cites W2942151359 @default.
• W3109020512 cites W2952265007 @default.
• W3109020512 cites W2954468805 @default.
• W3109020512 cites W2964061879 @default.
• W3109020512 cites W2969334203 @default.
• W3109020512 cites W2969356900 @default.
• W3109020512 cites W2974817476 @default.
• W3109020512 cites W3005089972 @default.
• W3109020512 cites W3006929350 @default.
• W3109020512 cites W3011656342 @default.
• W3109020512 cites W46288403 @default.
• W3109020512 doi "https://doi.org/10.3390/nu12123607" @default.
• W3109020512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7760876" @default.
• W3109020512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33255321" @default.
• W3109020512 hasPublicationYear "2020" @default.
• W3109020512 type Work @default.
• W3109020512 sameAs 3109020512 @default.
• W3109020512 citedByCount "12" @default.
• W3109020512 countsByYear W31090205122021 @default.
• W3109020512 countsByYear W31090205122022 @default.
• W3109020512 countsByYear W31090205122023 @default.
• W3109020512 crossrefType "journal-article" @default.
• W3109020512 hasAuthorship W3109020512A5007070631 @default.
• W3109020512 hasAuthorship W3109020512A5007555709 @default.
• W3109020512 hasAuthorship W3109020512A5013459788 @default.
• W3109020512 hasAuthorship W3109020512A5015882639 @default.
• W3109020512 hasAuthorship W3109020512A5021186201 @default.
• W3109020512 hasAuthorship W3109020512A5061401105 @default.
• W3109020512 hasAuthorship W3109020512A5062034700 @default.
• W3109020512 hasAuthorship W3109020512A5068349878 @default.
• W3109020512 hasAuthorship W3109020512A5072416977 @default.
• W3109020512 hasBestOaLocation W31090205121 @default.
• W3109020512 hasConcept C142724271 @default.

• next