Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109452817> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3109452817 endingPage "409" @default.
- W3109452817 startingPage "407" @default.
- W3109452817 abstract "Testosterone replacement therapy is widely used for the treatment of late-onset hypogonadism (LOH). However, because exogenous testosterone can suppress the hypothalamic-pituitary-gonadal axis through negative feedback, testosterone replacement therapy may lead to secondary spermatogenic failure and subsequent infertility. We report our experience with male infertility in patients who had received testosterone for LOH. Six of the 4,375 patients who visited our clinic for infertility evaluation had received testosterone replacement therapy for LOH. In these patients, testosterone was administered for 3 to 12 months. In 5 of these 6 patients, blood levels of gonadotropins were markedly suppressed, suggesting hypogonadotropic hypogonadism. In the remaining 1 patient, blood luteinizing hormone and follicle stimulating hormone levels were within the standard reference ranges, but the testosterone level was elevated. Semen findings in these patients ranged from azoospermia to severe oligospermia. Testosterone administration was immediately stopped in all patients. Of the 3 patients who needed prompt recovery of spermatogenesis, 2 received human chorionic gonadotropin (hCG) injection and 1 received clomiphene orally. Semen findings were significantly improved in all patients, except one who was treated with hCG for only one month. Although recovery of spermatogenesis is generally favorable after cessation of testosterone replacement therapy, the recovery period is highly variable among patients. Clinicians treating LOH must recognize that testosterone administration is contraindicated in men who desire to maintain future fertility. LOH patients who wish to preserve fertility should be considered for treatment with clomiphene or hCG." @default.
- W3109452817 created "2020-12-07" @default.
- W3109452817 creator A5004082835 @default.
- W3109452817 creator A5054718756 @default.
- W3109452817 date "2020-11-01" @default.
- W3109452817 modified "2023-09-24" @default.
- W3109452817 title "[Risk of Male Infertility Due to Testosterone Replacement Therapy for Late-Onset Hypogonadism (LOH)]." @default.
- W3109452817 doi "https://doi.org/10.14989/actauroljap_66_11_407" @default.
- W3109452817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33271659" @default.
- W3109452817 hasPublicationYear "2020" @default.
- W3109452817 type Work @default.
- W3109452817 sameAs 3109452817 @default.
- W3109452817 citedByCount "2" @default.
- W3109452817 countsByYear W31094528172021 @default.
- W3109452817 countsByYear W31094528172022 @default.
- W3109452817 crossrefType "journal-article" @default.
- W3109452817 hasAuthorship W3109452817A5004082835 @default.
- W3109452817 hasAuthorship W3109452817A5054718756 @default.
- W3109452817 hasConcept C123765429 @default.
- W3109452817 hasConcept C126322002 @default.
- W3109452817 hasConcept C134018914 @default.
- W3109452817 hasConcept C2775948956 @default.
- W3109452817 hasConcept C2777338322 @default.
- W3109452817 hasConcept C2777420699 @default.
- W3109452817 hasConcept C2777688143 @default.
- W3109452817 hasConcept C2778575703 @default.
- W3109452817 hasConcept C2778782382 @default.
- W3109452817 hasConcept C2779234561 @default.
- W3109452817 hasConcept C2779279165 @default.
- W3109452817 hasConcept C2779279991 @default.
- W3109452817 hasConcept C2781255401 @default.
- W3109452817 hasConcept C29456083 @default.
- W3109452817 hasConcept C54355233 @default.
- W3109452817 hasConcept C71315377 @default.
- W3109452817 hasConcept C71924100 @default.
- W3109452817 hasConcept C86803240 @default.
- W3109452817 hasConceptScore W3109452817C123765429 @default.
- W3109452817 hasConceptScore W3109452817C126322002 @default.
- W3109452817 hasConceptScore W3109452817C134018914 @default.
- W3109452817 hasConceptScore W3109452817C2775948956 @default.
- W3109452817 hasConceptScore W3109452817C2777338322 @default.
- W3109452817 hasConceptScore W3109452817C2777420699 @default.
- W3109452817 hasConceptScore W3109452817C2777688143 @default.
- W3109452817 hasConceptScore W3109452817C2778575703 @default.
- W3109452817 hasConceptScore W3109452817C2778782382 @default.
- W3109452817 hasConceptScore W3109452817C2779234561 @default.
- W3109452817 hasConceptScore W3109452817C2779279165 @default.
- W3109452817 hasConceptScore W3109452817C2779279991 @default.
- W3109452817 hasConceptScore W3109452817C2781255401 @default.
- W3109452817 hasConceptScore W3109452817C29456083 @default.
- W3109452817 hasConceptScore W3109452817C54355233 @default.
- W3109452817 hasConceptScore W3109452817C71315377 @default.
- W3109452817 hasConceptScore W3109452817C71924100 @default.
- W3109452817 hasConceptScore W3109452817C86803240 @default.
- W3109452817 hasIssue "11" @default.
- W3109452817 hasLocation W31094528171 @default.
- W3109452817 hasOpenAccess W3109452817 @default.
- W3109452817 hasPrimaryLocation W31094528171 @default.
- W3109452817 hasRelatedWork W120991595 @default.
- W3109452817 hasRelatedWork W141079520 @default.
- W3109452817 hasRelatedWork W1529918126 @default.
- W3109452817 hasRelatedWork W1987979860 @default.
- W3109452817 hasRelatedWork W1999379253 @default.
- W3109452817 hasRelatedWork W2036601765 @default.
- W3109452817 hasRelatedWork W2052573724 @default.
- W3109452817 hasRelatedWork W2063229317 @default.
- W3109452817 hasRelatedWork W2119125983 @default.
- W3109452817 hasRelatedWork W2166246039 @default.
- W3109452817 hasRelatedWork W2264972756 @default.
- W3109452817 hasRelatedWork W2392913542 @default.
- W3109452817 hasRelatedWork W2439398246 @default.
- W3109452817 hasRelatedWork W2804130566 @default.
- W3109452817 hasRelatedWork W2913055164 @default.
- W3109452817 hasRelatedWork W2921741258 @default.
- W3109452817 hasRelatedWork W2969560753 @default.
- W3109452817 hasRelatedWork W3030198980 @default.
- W3109452817 hasRelatedWork W3109869662 @default.
- W3109452817 hasRelatedWork W3167249606 @default.
- W3109452817 hasVolume "66" @default.
- W3109452817 isParatext "false" @default.
- W3109452817 isRetracted "false" @default.
- W3109452817 magId "3109452817" @default.
- W3109452817 workType "article" @default.