FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109476619> ?p ?o ?g. }

• W3109476619 abstract "Abstract The evolutionary emergence of the first animals is thought to have been intimately associated to the formation of a primitive endomesodermal gut ( i.e gastrulation) from ancestral multi-cellular spheres, blastulae, more than 700 million years ago. However, the biochemical cues having been at the origin of endomesoderm formation remain a mystery. Here we find that hydrodynamic mechanical strains developed by sea wavelets on pre-bilaterian Nematostella vectensis and pre-metazoan Choanoeca flexa representatives, which common ancestor dates back to more than 700 million years ago, can trigger gastrulation in a Myo-II dependent mechanotransductive process. Gastrulation in turn induces endomesoderm first biochemical specification through the mechanical activation of the βcat pathway in pre-bilaterian Nematostella vectensis , like in Drosophila and zebrafish embryos, which common ancestor dates back to 600-700 million years ago. These observations converge to animal emergence that has been mechanotransductively triggered by wavelet mechanical strains on the sea-shore in multicellular choanoflagellates through Myo-II more than 700 million years ago, a process achieved in first metazoan through mechanosensitive Y654-containing βcat evolutionary emergence found as conserved in all metazoan. One sentence summary Marine hydrodynamic strains have activated first gastric organ formation from ancestral pre-animal cell colonies." @default.
• W3109476619 created "2020-12-07" @default.
• W3109476619 creator A5007201618 @default.
• W3109476619 creator A5013711949 @default.
• W3109476619 creator A5052359416 @default.
• W3109476619 creator A5064591937 @default.
• W3109476619 creator A5065144318 @default.
• W3109476619 creator A5084362015 @default.
• W3109476619 creator A5086107509 @default.
• W3109476619 creator A5089052412 @default.
• W3109476619 creator A5090842594 @default.
• W3109476619 date "2020-12-03" @default.
• W3109476619 modified "2023-09-25" @default.
• W3109476619 title "Evolutionary Emergence of First Animal Organisms Triggered by Environmental Mechano-Biochemical Marine Stimulation" @default.
• W3109476619 cites W1661176175 @default.
• W3109476619 cites W1951020172 @default.
• W3109476619 cites W1975132186 @default.
• W3109476619 cites W1989889624 @default.
• W3109476619 cites W1992150639 @default.
• W3109476619 cites W2001489844 @default.
• W3109476619 cites W2001713897 @default.
• W3109476619 cites W2007399351 @default.
• W3109476619 cites W2007916811 @default.
• W3109476619 cites W2008775946 @default.
• W3109476619 cites W2009774391 @default.
• W3109476619 cites W2011974546 @default.
• W3109476619 cites W2026652581 @default.
• W3109476619 cites W2048305477 @default.
• W3109476619 cites W2053492859 @default.
• W3109476619 cites W2055036199 @default.
• W3109476619 cites W2055558330 @default.
• W3109476619 cites W2056832869 @default.
• W3109476619 cites W2057007227 @default.
• W3109476619 cites W2058096164 @default.
• W3109476619 cites W2063933675 @default.
• W3109476619 cites W2087805577 @default.
• W3109476619 cites W2098047064 @default.
• W3109476619 cites W2099491263 @default.
• W3109476619 cites W2107973236 @default.
• W3109476619 cites W2124772083 @default.
• W3109476619 cites W2134208433 @default.
• W3109476619 cites W2140304975 @default.
• W3109476619 cites W2141075109 @default.
• W3109476619 cites W2146047000 @default.
• W3109476619 cites W2152839099 @default.
• W3109476619 cites W2156859975 @default.
• W3109476619 cites W2159606671 @default.
• W3109476619 cites W2581194523 @default.
• W3109476619 cites W2734728802 @default.
• W3109476619 cites W2750368203 @default.
• W3109476619 cites W2790556376 @default.
• W3109476619 cites W2803977313 @default.
• W3109476619 cites W2950044375 @default.
• W3109476619 cites W2967768480 @default.
• W3109476619 cites W2980718989 @default.
• W3109476619 doi "https://doi.org/10.1101/2020.12.03.407668" @default.
• W3109476619 hasPublicationYear "2020" @default.
• W3109476619 type Work @default.
• W3109476619 sameAs 3109476619 @default.
• W3109476619 citedByCount "1" @default.
• W3109476619 countsByYear W31094766192022 @default.
• W3109476619 crossrefType "posted-content" @default.
• W3109476619 hasAuthorship W3109476619A5007201618 @default.
• W3109476619 hasAuthorship W3109476619A5013711949 @default.
• W3109476619 hasAuthorship W3109476619A5052359416 @default.
• W3109476619 hasAuthorship W3109476619A5064591937 @default.
• W3109476619 hasAuthorship W3109476619A5065144318 @default.
• W3109476619 hasAuthorship W3109476619A5084362015 @default.
• W3109476619 hasAuthorship W3109476619A5086107509 @default.
• W3109476619 hasAuthorship W3109476619A5089052412 @default.
• W3109476619 hasAuthorship W3109476619A5090842594 @default.
• W3109476619 hasBestOaLocation W31094766191 @default.
• W3109476619 hasConcept C104317684 @default.
• W3109476619 hasConcept C129536746 @default.
• W3109476619 hasConcept C151730666 @default.
• W3109476619 hasConcept C196843134 @default.
• W3109476619 hasConcept C197583594 @default.
• W3109476619 hasConcept C2776878037 @default.
• W3109476619 hasConcept C2780417240 @default.
• W3109476619 hasConcept C54355233 @default.
• W3109476619 hasConcept C74318829 @default.
• W3109476619 hasConcept C78458016 @default.
• W3109476619 hasConcept C86803240 @default.
• W3109476619 hasConcept C87073359 @default.
• W3109476619 hasConcept C90132467 @default.
• W3109476619 hasConceptScore W3109476619C104317684 @default.
• W3109476619 hasConceptScore W3109476619C129536746 @default.
• W3109476619 hasConceptScore W3109476619C151730666 @default.
• W3109476619 hasConceptScore W3109476619C196843134 @default.
• W3109476619 hasConceptScore W3109476619C197583594 @default.
• W3109476619 hasConceptScore W3109476619C2776878037 @default.
• W3109476619 hasConceptScore W3109476619C2780417240 @default.
• W3109476619 hasConceptScore W3109476619C54355233 @default.
• W3109476619 hasConceptScore W3109476619C74318829 @default.
• W3109476619 hasConceptScore W3109476619C78458016 @default.
• W3109476619 hasConceptScore W3109476619C86803240 @default.
• W3109476619 hasConceptScore W3109476619C87073359 @default.
• W3109476619 hasConceptScore W3109476619C90132467 @default.
• W3109476619 hasLocation W31094766191 @default.
• W3109476619 hasOpenAccess W3109476619 @default.

• next