Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109499085> ?p ?o ?g. }
- W3109499085 endingPage "2787" @default.
- W3109499085 startingPage "2787" @default.
- W3109499085 abstract "Thermally induced phase separation followed by freeze drying has been used to prepare biodegradable and biocompatible scaffolds with interconnected 3D microporous structures from poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) copolymers containing 5 and 12 wt % of 3-hydroxyvalerate (HV). Solutions of PHBV in 1,4-dioxane, underwent phase separation by cooling under two different thermal gradients (at −25 °C and −5 °C). The cloud point and crystallization temperature of the polymer solutions were determined by turbidimetry and differential scanning calorimetry, respectively. Parameters affecting the phase separation mechanism such as variation of both the cooling process and the composition of the PHBV copolymer were investigated. Afterwards, the influence of these variables on the morphology of the porous structure and the final mechanical properties (i.e., rigidity and damping) was evaluated via scanning electron microscopy and dynamic mechanical thermal analysis, respectively. While the morphology of the scaffolds was considerably affected by polymer crystallization upon a slow cooling rate, the effect of solvent crystallization was more evident at either high hydroxyvalerate content (i.e., 12 wt % of HV) or high cooling rate. The decrease in the HV content gave rise to scaffolds with greater stiffness because of their higher degree of crystallinity, being also noticeable the greater consistency of the structure attained when the cooling rate was higher. Scaffolds were fully biocompatible supports for cell adhesion and proliferation in 3D cultures and show potential application as a tool for tissue regeneration." @default.
- W3109499085 created "2020-12-07" @default.
- W3109499085 creator A5009977084 @default.
- W3109499085 creator A5018830242 @default.
- W3109499085 creator A5042362586 @default.
- W3109499085 creator A5071948389 @default.
- W3109499085 creator A5075536330 @default.
- W3109499085 creator A5078385802 @default.
- W3109499085 date "2020-11-25" @default.
- W3109499085 modified "2023-10-14" @default.
- W3109499085 title "Poly(hydroxybutyrate-co-hydroxyvalerate) Porous Matrices from Thermally Induced Phase Separation" @default.
- W3109499085 cites W1510977144 @default.
- W3109499085 cites W1971410121 @default.
- W3109499085 cites W1972393679 @default.
- W3109499085 cites W1987561926 @default.
- W3109499085 cites W1989844764 @default.
- W3109499085 cites W2006974802 @default.
- W3109499085 cites W2008569673 @default.
- W3109499085 cites W2012025608 @default.
- W3109499085 cites W2013382702 @default.
- W3109499085 cites W2016438484 @default.
- W3109499085 cites W2019106272 @default.
- W3109499085 cites W2026457034 @default.
- W3109499085 cites W2034884329 @default.
- W3109499085 cites W2039107753 @default.
- W3109499085 cites W2039517105 @default.
- W3109499085 cites W2052927598 @default.
- W3109499085 cites W2053484261 @default.
- W3109499085 cites W2062978844 @default.
- W3109499085 cites W2084322712 @default.
- W3109499085 cites W2088113615 @default.
- W3109499085 cites W2103745164 @default.
- W3109499085 cites W2109544562 @default.
- W3109499085 cites W2113027350 @default.
- W3109499085 cites W2114126007 @default.
- W3109499085 cites W2124195334 @default.
- W3109499085 cites W2144775265 @default.
- W3109499085 cites W2149728689 @default.
- W3109499085 cites W2154172743 @default.
- W3109499085 cites W2154659743 @default.
- W3109499085 cites W2167680304 @default.
- W3109499085 cites W2315029481 @default.
- W3109499085 cites W2802156105 @default.
- W3109499085 cites W2811194914 @default.
- W3109499085 cites W2898256311 @default.
- W3109499085 cites W2927326231 @default.
- W3109499085 cites W2940324129 @default.
- W3109499085 cites W2957374463 @default.
- W3109499085 cites W3033616601 @default.
- W3109499085 cites W3068732794 @default.
- W3109499085 cites W3084372751 @default.
- W3109499085 cites W4211245217 @default.
- W3109499085 cites W4241286643 @default.
- W3109499085 cites W4246421982 @default.
- W3109499085 doi "https://doi.org/10.3390/polym12122787" @default.
- W3109499085 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7760090" @default.
- W3109499085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33255699" @default.
- W3109499085 hasPublicationYear "2020" @default.
- W3109499085 type Work @default.
- W3109499085 sameAs 3109499085 @default.
- W3109499085 citedByCount "6" @default.
- W3109499085 countsByYear W31094990852021 @default.
- W3109499085 countsByYear W31094990852022 @default.
- W3109499085 countsByYear W31094990852023 @default.
- W3109499085 crossrefType "journal-article" @default.
- W3109499085 hasAuthorship W3109499085A5009977084 @default.
- W3109499085 hasAuthorship W3109499085A5018830242 @default.
- W3109499085 hasAuthorship W3109499085A5042362586 @default.
- W3109499085 hasAuthorship W3109499085A5071948389 @default.
- W3109499085 hasAuthorship W3109499085A5075536330 @default.
- W3109499085 hasAuthorship W3109499085A5078385802 @default.
- W3109499085 hasBestOaLocation W31094990851 @default.
- W3109499085 hasConcept C110530677 @default.
- W3109499085 hasConcept C121332964 @default.
- W3109499085 hasConcept C127413603 @default.
- W3109499085 hasConcept C15920480 @default.
- W3109499085 hasConcept C159985019 @default.
- W3109499085 hasConcept C178790620 @default.
- W3109499085 hasConcept C185592680 @default.
- W3109499085 hasConcept C192562407 @default.
- W3109499085 hasConcept C203036418 @default.
- W3109499085 hasConcept C26771246 @default.
- W3109499085 hasConcept C39519442 @default.
- W3109499085 hasConcept C42360764 @default.
- W3109499085 hasConcept C44280652 @default.
- W3109499085 hasConcept C46275449 @default.
- W3109499085 hasConcept C521977710 @default.
- W3109499085 hasConcept C6648577 @default.
- W3109499085 hasConcept C86381522 @default.
- W3109499085 hasConcept C97355855 @default.
- W3109499085 hasConceptScore W3109499085C110530677 @default.
- W3109499085 hasConceptScore W3109499085C121332964 @default.
- W3109499085 hasConceptScore W3109499085C127413603 @default.
- W3109499085 hasConceptScore W3109499085C15920480 @default.
- W3109499085 hasConceptScore W3109499085C159985019 @default.
- W3109499085 hasConceptScore W3109499085C178790620 @default.
- W3109499085 hasConceptScore W3109499085C185592680 @default.
- W3109499085 hasConceptScore W3109499085C192562407 @default.