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• W3109510012 endingPage "2062" @default.
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• W3109510012 abstract "Most children now survive cardiac surgery, and the focus of quality improvement initiatives has shifted toward more complex outcome measures. The aim of this investigation was to study the impact of early postoperative morbidities on parent-reported patient quality of life and parental anxiety or depression over 6 months.This prospective case-matched cohort study was conducted in 5 UK children's cardiac centers. Measures of impact for patient categories of single morbidity, multiple morbidities, and extracorporeal life support (ECLS) were compared with no morbidity. The measures used were the Pediatric Quality of Life Inventory (PedsQL) and the 4-item Patient Health Questionnaire (PHQ-4) at 6 weeks and 6 months postoperatively. The study modeled the outcomes using mixed effects regression, adjusting for case mix and clustering within centers.The study included 666 patients who underwent operation at a median age of 81 days (interquartile range, 10 to 325 days). At 6-week follow-up, significant adjusted differences to the reference group with no morbidity were found for total PedsQL scores, which were lower in patients with ECLS (P = .01), multiple morbidities (P < .001), and a single morbidity (P = .04), as well as the proportion of parents with anxiety and depression, which were higher in the group with multiple morbidities (P = .04 and P = .01, respectively). At 6 months, measures had improved in all morbidity groups. The only significant adjusted difference in the reference group was for physical PedsQL scores in ECLS (P = .04) and multiple morbidities (P < .01).Patient and parent well-being are strongly influenced by postoperative morbidities early after surgery, with improvement by 6 months. Family psychological support and holistic rehabilitation are vital for children who experience postoperative morbidities." @default.
• W3109510012 created "2020-12-07" @default.
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• W3109510012 date "2021-12-01" @default.
• W3109510012 modified "2023-10-05" @default.
• W3109510012 title "Morbidities After Cardiac Surgery: Impact on Children’s Quality of Life and Parents’ Mental Health" @default.
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• W3109510012 doi "https://doi.org/10.1016/j.athoracsur.2020.11.003" @default.
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