Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109581708> ?p ?o ?g. }
- W3109581708 endingPage "20200614" @default.
- W3109581708 startingPage "20200614" @default.
- W3109581708 abstract "Papillary muscles serve as attachment points for chordae tendineae which anchor and position mitral valve leaflets for proper coaptation. As the ventricle contracts, the papillary muscles translate and rotate, impacting chordae and leaflet kinematics; this motion can be significantly affected in a diseased heart. In ex vivo heart simulation, an explanted valve is subjected to physiologic conditions and can be adapted to mimic a disease state, thus providing a valuable tool to quantitatively analyse biomechanics and optimize surgical valve repair. However, without the inclusion of papillary muscle motion, current simulators are limited in their ability to accurately replicate cardiac biomechanics. We developed and implemented image-guided papillary muscle (IPM) robots to mimic the precise motion of papillary muscles. The IPM robotic system was designed with six degrees of freedom to fully capture the native motion. Mathematical analysis was used to avoid singularity conditions, and a supercomputing cluster enabled the calculation of the system's reachable workspace. The IPM robots were implemented in our heart simulator with motion prescribed by high-resolution human computed tomography images, revealing that papillary muscle motion significantly impacts the chordae force profile. Our IPM robotic system represents a significant advancement for ex vivo simulation, enabling more reliable cardiac simulations and repair optimizations." @default.
- W3109581708 created "2020-12-07" @default.
- W3109581708 creator A5009952595 @default.
- W3109581708 creator A5012362703 @default.
- W3109581708 creator A5021415319 @default.
- W3109581708 creator A5024806532 @default.
- W3109581708 creator A5025431291 @default.
- W3109581708 creator A5040270973 @default.
- W3109581708 creator A5040657213 @default.
- W3109581708 creator A5052480722 @default.
- W3109581708 creator A5063472572 @default.
- W3109581708 creator A5066110419 @default.
- W3109581708 creator A5079199043 @default.
- W3109581708 creator A5085500768 @default.
- W3109581708 creator A5085837483 @default.
- W3109581708 creator A5090742636 @default.
- W3109581708 date "2020-12-01" @default.
- W3109581708 modified "2023-10-12" @default.
- W3109581708 title "Biomimetic six-axis robots replicate human cardiac papillary muscle motion: pioneering the next generation of biomechanical heart simulator technology" @default.
- W3109581708 cites W1812362313 @default.
- W3109581708 cites W1834840029 @default.
- W3109581708 cites W1979974111 @default.
- W3109581708 cites W1985848686 @default.
- W3109581708 cites W1992976895 @default.
- W3109581708 cites W2000301791 @default.
- W3109581708 cites W2006326119 @default.
- W3109581708 cites W2006823239 @default.
- W3109581708 cites W2009357494 @default.
- W3109581708 cites W2021307306 @default.
- W3109581708 cites W2023939834 @default.
- W3109581708 cites W2028968849 @default.
- W3109581708 cites W2037933181 @default.
- W3109581708 cites W2068850287 @default.
- W3109581708 cites W2100552848 @default.
- W3109581708 cites W2135448280 @default.
- W3109581708 cites W2158448541 @default.
- W3109581708 cites W2161573903 @default.
- W3109581708 cites W2574063486 @default.
- W3109581708 cites W2767369610 @default.
- W3109581708 cites W2770542903 @default.
- W3109581708 cites W2792736914 @default.
- W3109581708 cites W2900887435 @default.
- W3109581708 cites W2920266751 @default.
- W3109581708 cites W2953532140 @default.
- W3109581708 cites W2981416016 @default.
- W3109581708 cites W3003705632 @default.
- W3109581708 cites W3004087171 @default.
- W3109581708 cites W3025466134 @default.
- W3109581708 doi "https://doi.org/10.1098/rsif.2020.0614" @default.
- W3109581708 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7811588" @default.
- W3109581708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33259750" @default.
- W3109581708 hasPublicationYear "2020" @default.
- W3109581708 type Work @default.
- W3109581708 sameAs 3109581708 @default.
- W3109581708 citedByCount "11" @default.
- W3109581708 countsByYear W31095817082021 @default.
- W3109581708 countsByYear W31095817082022 @default.
- W3109581708 countsByYear W31095817082023 @default.
- W3109581708 crossrefType "journal-article" @default.
- W3109581708 hasAuthorship W3109581708A5009952595 @default.
- W3109581708 hasAuthorship W3109581708A5012362703 @default.
- W3109581708 hasAuthorship W3109581708A5021415319 @default.
- W3109581708 hasAuthorship W3109581708A5024806532 @default.
- W3109581708 hasAuthorship W3109581708A5025431291 @default.
- W3109581708 hasAuthorship W3109581708A5040270973 @default.
- W3109581708 hasAuthorship W3109581708A5040657213 @default.
- W3109581708 hasAuthorship W3109581708A5052480722 @default.
- W3109581708 hasAuthorship W3109581708A5063472572 @default.
- W3109581708 hasAuthorship W3109581708A5066110419 @default.
- W3109581708 hasAuthorship W3109581708A5079199043 @default.
- W3109581708 hasAuthorship W3109581708A5085500768 @default.
- W3109581708 hasAuthorship W3109581708A5085837483 @default.
- W3109581708 hasAuthorship W3109581708A5090742636 @default.
- W3109581708 hasBestOaLocation W31095817081 @default.
- W3109581708 hasConcept C104114177 @default.
- W3109581708 hasConcept C105702510 @default.
- W3109581708 hasConcept C121332964 @default.
- W3109581708 hasConcept C136229726 @default.
- W3109581708 hasConcept C154945302 @default.
- W3109581708 hasConcept C164705383 @default.
- W3109581708 hasConcept C170700871 @default.
- W3109581708 hasConcept C2777274916 @default.
- W3109581708 hasConcept C2777543888 @default.
- W3109581708 hasConcept C2780870192 @default.
- W3109581708 hasConcept C39920418 @default.
- W3109581708 hasConcept C41008148 @default.
- W3109581708 hasConcept C44154836 @default.
- W3109581708 hasConcept C71924100 @default.
- W3109581708 hasConcept C74650414 @default.
- W3109581708 hasConceptScore W3109581708C104114177 @default.
- W3109581708 hasConceptScore W3109581708C105702510 @default.
- W3109581708 hasConceptScore W3109581708C121332964 @default.
- W3109581708 hasConceptScore W3109581708C136229726 @default.
- W3109581708 hasConceptScore W3109581708C154945302 @default.
- W3109581708 hasConceptScore W3109581708C164705383 @default.
- W3109581708 hasConceptScore W3109581708C170700871 @default.
- W3109581708 hasConceptScore W3109581708C2777274916 @default.
- W3109581708 hasConceptScore W3109581708C2777543888 @default.