FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109631008> ?p ?o ?g. }

• W3109631008 abstract "Abstract 5-methylcytosine (5mC) is a modified base often described as necessary for the proper regulation of genes and transposons and for the maintenance of genome integrity in plants. However, the extent of this dogma is limited by the current phylogenetic sampling of land plant species diversity. Here, we report that a monocot plant, Spirodela polyrhiza , has lost CG gene body methylation, genome-wide CHH methylation, and the presence or expression of several genes in the highly conserved RNA-directed DNA methylation (RdDM) pathway. It has also lost the CHH methyltransferase CHROMOMETHYLASE 2 . Consequently, the transcriptome is depleted of 24-nucleotide, heterochromatic, small interfering RNAs that act as guides for the deposition of 5mC to RdDM-targeted loci in all other currently sampled angiosperm genomes. Although the genome displays low levels of genome-wide 5mC primarily at LTR retrotransposons, CG maintenance methylation is still functional. In contrast, CHG methylation is weakly maintained even though H3K9me2 is present at loci dispersed throughout the euchromatin and highly enriched at regions likely demarcating pericentromeric regions. Collectively, these results illustrate that S. polyrhiza is maintaining CG and CHG methylation mostly at repeats in the absence of small RNAs. S. polyrhiza reproduces rapidly through clonal propagation in aquatic environments, which we hypothesize may enable low levels of maintenance methylation to persist in large populations. Significance Statement DNA methylation is a widespread chromatin modification that is regularly found in all plant species. By examining one aquatic duckweed species, Spirodela polyrhiza , we find that it has lost highly conserved genes involved in methylation of DNA at sites often associated with repetitive DNA, and within genes, however DNA methylation and heterochromatin is maintained during cell division at other sites. Consequently, small RNAs that normally guide methylation to silence repetitive DNA like retrotransposons are diminished. Despite the loss of a highly conserved methylation pathway, and the reduction of small RNAs that normally target repetitive DNA, transposons have not proliferated in the genome, perhaps due in part to the rapid, clonal growth lifestyle of duckweeds." @default.
• W3109631008 created "2020-12-07" @default.
• W3109631008 creator A5013432883 @default.
• W3109631008 creator A5048572596 @default.
• W3109631008 creator A5052413360 @default.
• W3109631008 creator A5065088502 @default.
• W3109631008 creator A5065847261 @default.
• W3109631008 creator A5066299455 @default.
• W3109631008 creator A5076526804 @default.
• W3109631008 creator A5088429228 @default.
• W3109631008 date "2020-12-03" @default.
• W3109631008 modified "2023-10-16" @default.
• W3109631008 title "Unusual predominance of maintenance DNA methylation in <i>Spirodela polyrhiza</i>" @default.
• W3109631008 cites W1681030413 @default.
• W3109631008 cites W1760031123 @default.
• W3109631008 cites W1910920621 @default.
• W3109631008 cites W1951480739 @default.
• W3109631008 cites W1975268045 @default.
• W3109631008 cites W1977171359 @default.
• W3109631008 cites W1979576560 @default.
• W3109631008 cites W1980436308 @default.
• W3109631008 cites W1984891757 @default.
• W3109631008 cites W1985658587 @default.
• W3109631008 cites W1987293097 @default.
• W3109631008 cites W1989568035 @default.
• W3109631008 cites W1999615280 @default.
• W3109631008 cites W1999644599 @default.
• W3109631008 cites W2016813268 @default.
• W3109631008 cites W2018249152 @default.
• W3109631008 cites W2019630339 @default.
• W3109631008 cites W2020173141 @default.
• W3109631008 cites W2025089507 @default.
• W3109631008 cites W2026887719 @default.
• W3109631008 cites W2041666611 @default.
• W3109631008 cites W2057162139 @default.
• W3109631008 cites W2067151470 @default.
• W3109631008 cites W2076556464 @default.
• W3109631008 cites W2079514282 @default.
• W3109631008 cites W2082694471 @default.
• W3109631008 cites W2083899560 @default.
• W3109631008 cites W2090829779 @default.
• W3109631008 cites W2101662726 @default.
• W3109631008 cites W2102619694 @default.
• W3109631008 cites W2103441770 @default.
• W3109631008 cites W2107314112 @default.
• W3109631008 cites W2123430325 @default.
• W3109631008 cites W2123846805 @default.
• W3109631008 cites W2124985265 @default.
• W3109631008 cites W2126371676 @default.
• W3109631008 cites W2148954829 @default.
• W3109631008 cites W2150183438 @default.
• W3109631008 cites W2151476452 @default.
• W3109631008 cites W2158898879 @default.
• W3109631008 cites W2163003877 @default.
• W3109631008 cites W2168031748 @default.
• W3109631008 cites W2171116394 @default.
• W3109631008 cites W2171808845 @default.
• W3109631008 cites W2172175748 @default.
• W3109631008 cites W2461153930 @default.
• W3109631008 cites W2462490406 @default.
• W3109631008 cites W2486293682 @default.
• W3109631008 cites W2497722199 @default.
• W3109631008 cites W2515614959 @default.
• W3109631008 cites W2537008587 @default.
• W3109631008 cites W2566469243 @default.
• W3109631008 cites W2580815116 @default.
• W3109631008 cites W2594272959 @default.
• W3109631008 cites W2747948838 @default.
• W3109631008 cites W2778865418 @default.
• W3109631008 cites W2882989368 @default.
• W3109631008 cites W2900427709 @default.
• W3109631008 cites W2905091696 @default.
• W3109631008 cites W2949906131 @default.
• W3109631008 cites W2950103832 @default.
• W3109631008 cites W2952286808 @default.
• W3109631008 cites W2957310322 @default.
• W3109631008 cites W2965777662 @default.
• W3109631008 cites W2971606785 @default.
• W3109631008 cites W2972636473 @default.
• W3109631008 cites W3002963569 @default.
• W3109631008 cites W3007462267 @default.
• W3109631008 cites W3020413084 @default.
• W3109631008 cites W3092207169 @default.
• W3109631008 cites W4367662390 @default.
• W3109631008 doi "https://doi.org/10.1101/2020.12.03.410332" @default.
• W3109631008 hasPublicationYear "2020" @default.
• W3109631008 type Work @default.
• W3109631008 sameAs 3109631008 @default.
• W3109631008 citedByCount "5" @default.
• W3109631008 countsByYear W31096310082022 @default.
• W3109631008 countsByYear W31096310082023 @default.
• W3109631008 crossrefType "posted-content" @default.
• W3109631008 hasAuthorship W3109631008A5013432883 @default.
• W3109631008 hasAuthorship W3109631008A5048572596 @default.
• W3109631008 hasAuthorship W3109631008A5052413360 @default.
• W3109631008 hasAuthorship W3109631008A5065088502 @default.
• W3109631008 hasAuthorship W3109631008A5065847261 @default.
• W3109631008 hasAuthorship W3109631008A5066299455 @default.
• W3109631008 hasAuthorship W3109631008A5076526804 @default.
• W3109631008 hasAuthorship W3109631008A5088429228 @default.

• next