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- W3109686908 abstract "Bluetongue (BT) is a vector-borne viral OIE-listed disease of wild and domestic ruminants caused by bluetongue virus (BTV). BT has severe economic repercussions for the livestock industry due to direct losses caused by the infection but also due to indirect losses as a result of restrictions on animal trade. Since 1998, Southern Europe and the Mediterranean basin have experienced multiple incursions of different strains belonging to different serotypes and topotypes of BTV. In 2016 a BT outbreak occurred in Tunisia when the etiological agent was characterized as a novel western BTV serotype 3 strain. One year after the notification in Tunisia, BTV-3 outbreaks were evidenced in Sicily and Sardinia. Considering the history of the epidemiology of BTV in the Mediterranean basin and the absence of specific vaccines, a novel BTV-3 certainly represents a risk for the European livestock industry. Therefore, in this thesis several aspects were analyzed including the development of a specific and accurate real time RT-PCR for the detection of BTV-3 RNA, the analysis of BTV-3 spread by means of virological and serological methods within the particular emphasis on a genome characterization of BTV-3 using a next generation sequencing (NGS), a novel molecular diagnostic technique." @default.
- W3109686908 created "2020-12-07" @default.
- W3109686908 creator A5040476767 @default.
- W3109686908 date "2019-10-11" @default.
- W3109686908 modified "2023-09-28" @default.
- W3109686908 title "CHARACTERIZATION OF EMERGING BLUETONGUE VIRUS SEROTYPE 3 STRAINS IN THE MEDITERRANEAN BASIN BY NEXT GENERATION SEQUENCING" @default.
- W3109686908 hasPublicationYear "2019" @default.
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