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- W3109702571 endingPage "104993" @default.
- W3109702571 startingPage "104993" @default.
- W3109702571 abstract "Regenerative treatment protocols are an exciting prospect in the management of oral pathology, as they allow for tissues to be restored to their original form and function, as compared to the reparative healing mechanisms which currently govern the outcomes of the majority of dental treatment. Stem cell therapy presents with a great deal of untapped potential in this pursuit of tissue regeneration, and, in particular, mesenchymal stem cells (MSCs) derived from dental tissues are of specific relevance with regards to their applications in engineering craniofacial tissues. A number of mediatory factors are involved in modulating the actions of dental MSCs, and, of these, insulin like growth factors (IGFs) are known to have potent effects in governing the behavior of these cells. The IGF family comprises a number of primary ligands, receptors, and binding proteins which are known to modulate the key properties of dental MSCs, such as their proliferation rates, differentiation potential, and mineralisation. The aims of this review are three-fold: (i) to present an overview of dental MSCs and the role of growth factors in modulating their characteristics, (ii) to discuss in greater detail the specific role of IGFs and the benefits they may convey for tissue engineering, and (iii) to provide a summary of potential for in vivo clinical translation of the current in vitro body of evidence." @default.
- W3109702571 created "2020-12-07" @default.
- W3109702571 creator A5015341152 @default.
- W3109702571 date "2021-02-01" @default.
- W3109702571 modified "2023-10-15" @default.
- W3109702571 title "The role of insulin-like growth factors in modulating the activity of dental mesenchymal stem cells" @default.
- W3109702571 cites W101346465 @default.
- W3109702571 cites W1494568828 @default.
- W3109702571 cites W1512049674 @default.
- W3109702571 cites W1526220366 @default.
- W3109702571 cites W1535524823 @default.
- W3109702571 cites W1563571616 @default.
- W3109702571 cites W1571696828 @default.
- W3109702571 cites W1833790620 @default.
- W3109702571 cites W1906021965 @default.
- W3109702571 cites W1963903617 @default.
- W3109702571 cites W1969653325 @default.
- W3109702571 cites W1969815370 @default.
- W3109702571 cites W1970351839 @default.
- W3109702571 cites W1970457474 @default.
- W3109702571 cites W1970947849 @default.
- W3109702571 cites W1973222840 @default.
- W3109702571 cites W1974765744 @default.
- W3109702571 cites W1979758830 @default.
- W3109702571 cites W1981314894 @default.
- W3109702571 cites W1981391452 @default.
- W3109702571 cites W1983167741 @default.
- W3109702571 cites W1989470426 @default.
- W3109702571 cites W1991585565 @default.
- W3109702571 cites W199263423 @default.
- W3109702571 cites W1994276113 @default.
- W3109702571 cites W2001054902 @default.
- W3109702571 cites W2003184912 @default.
- W3109702571 cites W2004298899 @default.
- W3109702571 cites W2005615653 @default.
- W3109702571 cites W2006355752 @default.
- W3109702571 cites W2009133023 @default.
- W3109702571 cites W2011066792 @default.
- W3109702571 cites W2011375280 @default.
- W3109702571 cites W2011626437 @default.
- W3109702571 cites W2016900858 @default.
- W3109702571 cites W2019209906 @default.
- W3109702571 cites W2021306369 @default.
- W3109702571 cites W2024579131 @default.
- W3109702571 cites W2025672621 @default.
- W3109702571 cites W2027423876 @default.
- W3109702571 cites W2027654288 @default.
- W3109702571 cites W2031338932 @default.
- W3109702571 cites W2032177706 @default.
- W3109702571 cites W2032206576 @default.
- W3109702571 cites W2033510042 @default.
- W3109702571 cites W2033797383 @default.
- W3109702571 cites W2034639184 @default.
- W3109702571 cites W2035183042 @default.
- W3109702571 cites W2035428418 @default.
- W3109702571 cites W2040121303 @default.
- W3109702571 cites W2040475565 @default.
- W3109702571 cites W2043155600 @default.
- W3109702571 cites W2044810442 @default.
- W3109702571 cites W2045159954 @default.
- W3109702571 cites W2046910768 @default.
- W3109702571 cites W2048121649 @default.
- W3109702571 cites W2049791447 @default.
- W3109702571 cites W2050664881 @default.
- W3109702571 cites W2051019115 @default.
- W3109702571 cites W2052664174 @default.
- W3109702571 cites W2053134566 @default.
- W3109702571 cites W2054326257 @default.
- W3109702571 cites W2055845246 @default.
- W3109702571 cites W2056522693 @default.
- W3109702571 cites W2059167141 @default.
- W3109702571 cites W2060495109 @default.
- W3109702571 cites W2061808486 @default.
- W3109702571 cites W2063347291 @default.
- W3109702571 cites W2063896517 @default.
- W3109702571 cites W2065958014 @default.
- W3109702571 cites W2072949048 @default.
- W3109702571 cites W2075020789 @default.
- W3109702571 cites W2076313228 @default.
- W3109702571 cites W2076542702 @default.
- W3109702571 cites W2076764173 @default.
- W3109702571 cites W2078363576 @default.
- W3109702571 cites W2083119665 @default.
- W3109702571 cites W2084598858 @default.
- W3109702571 cites W2084610733 @default.
- W3109702571 cites W2090176789 @default.
- W3109702571 cites W2096356357 @default.
- W3109702571 cites W2101850049 @default.
- W3109702571 cites W2102337509 @default.
- W3109702571 cites W2102726602 @default.
- W3109702571 cites W2103282616 @default.
- W3109702571 cites W2107141327 @default.
- W3109702571 cites W2107855917 @default.
- W3109702571 cites W2109538121 @default.
- W3109702571 cites W2111589765 @default.
- W3109702571 cites W2112980329 @default.
- W3109702571 cites W2115068897 @default.
- W3109702571 cites W2116085460 @default.