Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109794636> ?p ?o ?g. }
- W3109794636 endingPage "322" @default.
- W3109794636 startingPage "315" @default.
- W3109794636 abstract "Previous studies have demonstrated voluntary movement alterations as well as motor cortex excitability and plasticity changes in patients with mild cognitive impairment (MCI). To investigate the pathophysiology of movement abnormalities in MCI, we tested possible relationships between movement abnormalities and primary motor cortex alterations in patients. Fourteen amnestic MCI (aMCI) patients and 16 healthy controls were studied. Cognitive assessment was performed using clinical scales. Finger tapping was recorded by a motion analysis system. Transcranial magnetic stimulation was used to test the input/output curve of motor evoked potentials, intracortical inhibition, and short-latency afferent inhibition. Primary motor cortex plasticity was probed by theta burst stimulation. We investigated correlations between movement abnormalities, clinical scores, and cortical neurophysiological parameters. MCI patients showed less rhythmic movement but no other movement abnormalities. Cortical excitability measures were normal in patients, whereas plasticity was reduced. Movement rhythm abnormalities correlated with frontal dysfunction scores. Our study in MCI patients demonstrated abnormal voluntary movement and plasticity changes, with no correlation between the two. Altered rhythm correlated with frontal dysfunction. Our results contribute to the understanding of pathophysiological mechanisms of motor impairment in MCI." @default.
- W3109794636 created "2020-12-07" @default.
- W3109794636 creator A5000077437 @default.
- W3109794636 creator A5004706283 @default.
- W3109794636 creator A5022282541 @default.
- W3109794636 creator A5027858233 @default.
- W3109794636 creator A5049426253 @default.
- W3109794636 creator A5062557232 @default.
- W3109794636 creator A5070138379 @default.
- W3109794636 creator A5088158353 @default.
- W3109794636 date "2021-02-01" @default.
- W3109794636 modified "2023-10-02" @default.
- W3109794636 title "Motor dysfunction in mild cognitive impairment as tested by kinematic analysis and transcranial magnetic stimulation" @default.
- W3109794636 cites W1603646968 @default.
- W3109794636 cites W1620681165 @default.
- W3109794636 cites W1926592224 @default.
- W3109794636 cites W1963487177 @default.
- W3109794636 cites W1968429176 @default.
- W3109794636 cites W1975637677 @default.
- W3109794636 cites W1980827933 @default.
- W3109794636 cites W1981302247 @default.
- W3109794636 cites W1983293608 @default.
- W3109794636 cites W1988928342 @default.
- W3109794636 cites W1994281665 @default.
- W3109794636 cites W2010122394 @default.
- W3109794636 cites W2011940589 @default.
- W3109794636 cites W2013180901 @default.
- W3109794636 cites W2014043063 @default.
- W3109794636 cites W2015492395 @default.
- W3109794636 cites W2017717331 @default.
- W3109794636 cites W2018751524 @default.
- W3109794636 cites W2020439496 @default.
- W3109794636 cites W2025561374 @default.
- W3109794636 cites W2026463019 @default.
- W3109794636 cites W2028069634 @default.
- W3109794636 cites W2028436804 @default.
- W3109794636 cites W2040426212 @default.
- W3109794636 cites W2041300338 @default.
- W3109794636 cites W2042741137 @default.
- W3109794636 cites W2044488773 @default.
- W3109794636 cites W2050844226 @default.
- W3109794636 cites W2055649795 @default.
- W3109794636 cites W2059284083 @default.
- W3109794636 cites W2065066329 @default.
- W3109794636 cites W2065538322 @default.
- W3109794636 cites W2067495470 @default.
- W3109794636 cites W2067993536 @default.
- W3109794636 cites W2074760672 @default.
- W3109794636 cites W2078129640 @default.
- W3109794636 cites W2083920471 @default.
- W3109794636 cites W2085729374 @default.
- W3109794636 cites W2096410114 @default.
- W3109794636 cites W2107408109 @default.
- W3109794636 cites W2109807300 @default.
- W3109794636 cites W2112455323 @default.
- W3109794636 cites W2113199056 @default.
- W3109794636 cites W2127169747 @default.
- W3109794636 cites W2132155321 @default.
- W3109794636 cites W2134434659 @default.
- W3109794636 cites W2136022845 @default.
- W3109794636 cites W2138911066 @default.
- W3109794636 cites W2140358254 @default.
- W3109794636 cites W2145992702 @default.
- W3109794636 cites W2146051854 @default.
- W3109794636 cites W2156092714 @default.
- W3109794636 cites W2156587828 @default.
- W3109794636 cites W2169496098 @default.
- W3109794636 cites W2272219133 @default.
- W3109794636 cites W2292821836 @default.
- W3109794636 cites W2337662594 @default.
- W3109794636 cites W2469355841 @default.
- W3109794636 cites W2518267365 @default.
- W3109794636 cites W2582524520 @default.
- W3109794636 cites W2607458249 @default.
- W3109794636 cites W2789388366 @default.
- W3109794636 cites W2796025704 @default.
- W3109794636 cites W2808049432 @default.
- W3109794636 cites W2884197312 @default.
- W3109794636 cites W2893972840 @default.
- W3109794636 cites W2895904878 @default.
- W3109794636 cites W2973208504 @default.
- W3109794636 cites W2991113995 @default.
- W3109794636 cites W3002492948 @default.
- W3109794636 cites W3029648427 @default.
- W3109794636 cites W3048109944 @default.
- W3109794636 doi "https://doi.org/10.1016/j.clinph.2020.10.028" @default.
- W3109794636 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33450553" @default.
- W3109794636 hasPublicationYear "2021" @default.
- W3109794636 type Work @default.
- W3109794636 sameAs 3109794636 @default.
- W3109794636 citedByCount "17" @default.
- W3109794636 countsByYear W31097946362021 @default.
- W3109794636 countsByYear W31097946362022 @default.
- W3109794636 countsByYear W31097946362023 @default.
- W3109794636 crossrefType "journal-article" @default.
- W3109794636 hasAuthorship W3109794636A5000077437 @default.
- W3109794636 hasAuthorship W3109794636A5004706283 @default.
- W3109794636 hasAuthorship W3109794636A5022282541 @default.