Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109890626> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W3109890626 endingPage "52" @default.
- W3109890626 startingPage "43" @default.
- W3109890626 abstract "Background . Cerebral arteriovenous malformations (AVMs) are not static congenital lesions, but can grow, recur, and appear de novo after complete resection, embolization, or radiosurgery. Understanding the complex molecular biology of AVMs is critical to predicting their behavior during treatment and improving treatment outcomes. Objective . To study the dynamics of angiogenesis factors in the process of cerebral AVM embolization in order to develop a strategy for their personalized treatment. Design and methods . The study included 314 patients with AVM who received surgical treatment at the Department of Brain Vascular Surgery of the Polenov Neurosurgical Institute. Determined the level of vascular endothelial growth factor (VEGF), angiopoietin-2 (ANG-2) and matrix metalloproteinase-9 (MMP-9) in blood serum before and 24 hours after endovascular embolization using enzyme-linked immunosorbent assay (Personal Lab, Adaltis, Italy). Results . Primary patients (48.4 %) with AVM showed an increase in VEGF, MMP-9, ANG-2. A high level of VEGF and MMP-9 demonstrated AVM III grades according to Spetzler-Martin, AVM with a hemorrhagic flow type, with a deep drainage pattern, with afferents from the external carotid artery. The return to control values of all elevated growth factors after total embolization confirms the lack of potency for AVM recurrence. The absence of a decrease in aniogenesis factors after radical, according to angiographic criteria, embolization is a sign of subtotal AVM shutdown. Conclusion . A personalized concept of embolization in patients with a high risk of growth and recurrence has been formulated." @default.
- W3109890626 created "2020-12-07" @default.
- W3109890626 creator A5072333076 @default.
- W3109890626 creator A5073537442 @default.
- W3109890626 date "2020-11-27" @default.
- W3109890626 modified "2023-10-18" @default.
- W3109890626 title "Modern approaches to treatment of complex cerebral arteriovenous malformations" @default.
- W3109890626 doi "https://doi.org/10.18705/2311-4495-2020-7-5-43-52" @default.
- W3109890626 hasPublicationYear "2020" @default.
- W3109890626 type Work @default.
- W3109890626 sameAs 3109890626 @default.
- W3109890626 citedByCount "0" @default.
- W3109890626 crossrefType "journal-article" @default.
- W3109890626 hasAuthorship W3109890626A5072333076 @default.
- W3109890626 hasAuthorship W3109890626A5073537442 @default.
- W3109890626 hasBestOaLocation W31098906261 @default.
- W3109890626 hasConcept C126322002 @default.
- W3109890626 hasConcept C126838900 @default.
- W3109890626 hasConcept C141071460 @default.
- W3109890626 hasConcept C167734588 @default.
- W3109890626 hasConcept C2776035437 @default.
- W3109890626 hasConcept C2776694085 @default.
- W3109890626 hasConcept C2777025900 @default.
- W3109890626 hasConcept C2777802072 @default.
- W3109890626 hasConcept C2778749279 @default.
- W3109890626 hasConcept C2779603958 @default.
- W3109890626 hasConcept C2780387249 @default.
- W3109890626 hasConcept C2780394083 @default.
- W3109890626 hasConcept C2780643987 @default.
- W3109890626 hasConcept C2910939485 @default.
- W3109890626 hasConcept C509974204 @default.
- W3109890626 hasConcept C71924100 @default.
- W3109890626 hasConceptScore W3109890626C126322002 @default.
- W3109890626 hasConceptScore W3109890626C126838900 @default.
- W3109890626 hasConceptScore W3109890626C141071460 @default.
- W3109890626 hasConceptScore W3109890626C167734588 @default.
- W3109890626 hasConceptScore W3109890626C2776035437 @default.
- W3109890626 hasConceptScore W3109890626C2776694085 @default.
- W3109890626 hasConceptScore W3109890626C2777025900 @default.
- W3109890626 hasConceptScore W3109890626C2777802072 @default.
- W3109890626 hasConceptScore W3109890626C2778749279 @default.
- W3109890626 hasConceptScore W3109890626C2779603958 @default.
- W3109890626 hasConceptScore W3109890626C2780387249 @default.
- W3109890626 hasConceptScore W3109890626C2780394083 @default.
- W3109890626 hasConceptScore W3109890626C2780643987 @default.
- W3109890626 hasConceptScore W3109890626C2910939485 @default.
- W3109890626 hasConceptScore W3109890626C509974204 @default.
- W3109890626 hasConceptScore W3109890626C71924100 @default.
- W3109890626 hasIssue "5" @default.
- W3109890626 hasLocation W31098906261 @default.
- W3109890626 hasOpenAccess W3109890626 @default.
- W3109890626 hasPrimaryLocation W31098906261 @default.
- W3109890626 hasRelatedWork W1978647707 @default.
- W3109890626 hasRelatedWork W1994617869 @default.
- W3109890626 hasRelatedWork W2014923186 @default.
- W3109890626 hasRelatedWork W2015373192 @default.
- W3109890626 hasRelatedWork W2033449541 @default.
- W3109890626 hasRelatedWork W2314910440 @default.
- W3109890626 hasRelatedWork W2318270689 @default.
- W3109890626 hasRelatedWork W2564486148 @default.
- W3109890626 hasRelatedWork W2996951818 @default.
- W3109890626 hasRelatedWork W3023912429 @default.
- W3109890626 hasVolume "7" @default.
- W3109890626 isParatext "false" @default.
- W3109890626 isRetracted "false" @default.
- W3109890626 magId "3109890626" @default.
- W3109890626 workType "article" @default.