Matches in SemOpenAlex for { <https://semopenalex.org/work/W3109898711> ?p ?o ?g. }
- W3109898711 abstract "Class I ventral posterior dendritic arborisation (c1vpda) proprioceptive sensory neurons respond to contractions in the Drosophila larval body wall during crawling. Their dendritic branches run along the direction of contraction, possibly a functional requirement to maximise membrane curvature during crawling contractions. Although the molecular machinery of dendritic patterning in c1vpda has been extensively studied, the process leading to the precise elaboration of their comb-like shapes remains elusive. Here, to link dendrite shape with its proprioceptive role, we performed long-term, non-invasive, in vivo time-lapse imaging of c1vpda embryonic and larval morphogenesis to reveal a sequence of differentiation stages. We combined computer models and dendritic branch dynamics tracking to propose that distinct sequential phases of stochastic growth and retraction achieve efficient dendritic trees both in terms of wire and function. Our study shows how dendrite growth balances structure–function requirements, shedding new light on general principles of self-organisation in functionally specialised dendrites." @default.
- W3109898711 created "2020-12-07" @default.
- W3109898711 creator A5001143206 @default.
- W3109898711 creator A5030072419 @default.
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- W3109898711 creator A5059626898 @default.
- W3109898711 creator A5069233268 @default.
- W3109898711 creator A5078297857 @default.
- W3109898711 date "2020-11-26" @default.
- W3109898711 modified "2023-10-02" @default.
- W3109898711 title "Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction" @default.
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