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• W3109933439 abstract "Aim:Contrast-induced nephropathy (CIN) is associated high mortality and morbidity risks in the patients undergoing coronary angiography (CAG).Endocan, a new endothelial dysfunction biomarker, could be a potential immunoinflammatory biomarker for CIN.We investigated the possible association between serum endocan levels and CIN in the patients undergoing CAG. &#x0D; Material and Methods:We prospectively enrolled 92 patients undergoing CAG.For each patient, serum endocan levels were assessed at hospital admission before CAG.Contrast-induced nephropathy was defined as an increase in serum creatinine 25% or 0.5 mg/dl from baseline in the first 48 - 72 hours. &#x0D; Results:Overall, 32 cases (34.8%) of CIN were diagnosed.There were no significant differences between the two groups (CIN and without-CIN) in demographic data and general risk factors. 38 patients (41%) were performed percutaneous coronary intervention. Patients with CIN had higher serum endocan levels (3.68 ng/dl;IQR, 0.78-17.3 vs 1.81 ng/dl;IQR, 0.19-17.4, p:0,002) than patients without CIN. Additionaly; basal glomerular filtration rate, contrast volume, serum endocan level and left ventricle ejection fraction were detected as independent risk factors of CIN (p= 0.014, B:0.94, CI: 0.89-0.98, p= 0.024, B:2.55, CI:1.13-5.77, p= 0.026, B:2.45, CI:1.11-5.42, p= 0.044, B:0.91, CI:0.83-1.43, respectively). &#x0D; Conclusion:In patients undergoing CAG, high serum endocan levels could be associated with an increased risk for CIN." @default.
• W3109933439 created "2020-12-07" @default.
• W3109933439 creator A5026932825 @default.
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• W3109933439 date "2020-12-30" @default.
• W3109933439 modified "2023-09-26" @default.
• W3109933439 title "The relationship between serum endocan levels with the presence of contrast-induced nephropathy in patients undergoing coronary angiography" @default.
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• W3109933439 doi "https://doi.org/10.18663/tjcl.720147" @default.
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