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• W3109958166 abstract "Background The risk of spontaneous abortion in patients with polycystic ovary syndrome (PCOS) undergoing assisted reproductive treatment (ART) is higher than that in patients without PCOS, however, no definitive risk factors have been confirmed to associate with the high spontaneous abortion rate in PCOS patients undergoing ART. This study was performed to assess the impact of relevant risk factors on spontaneous abortion in patients with PCOS. Clinical questions were formulated and organized according to the PICOS principle. Methods A systematic review and meta-analysis were conducted on all published studies on PCOS and spontaneous abortion in Embase, PubMed, Web of Science and Cochrane Library. Related risk factors included body mass index (BMI), age, insulin resistance (IR), hyperandrogenism, and chromosome aberrations. All patients were diagnosed as PCOS using the Rotterdam criteria. The primary endpoint was miscarriage and live birth rate. Fixed-effect models were used to analyze homogeneous data, and subgroup and sensitivity analyses were performed on heterogeneous data. The source of heterogeneity was evaluated, and the random effect model was used to summarize the heterogeneity. Results Among 1836 retrieved articles, 22 were eligible and included in the analysis with 11182 patients. High BMI (OR = 1.48, 95% CI [1.32, 1.67], MD = 1.35, 95% CI [0.58,2.12]) and insulin resistance (MD = 0.32, 95% CI [0.15, 0.49]) were associated with an increased risk of spontaneous abortion in PCOS patients undergoing ART. Older age (OR = 0.29, 95% CI [0.29, 0.44], MD = 2.01, 95% CI [0.04, 4.18]), embryonic chromosomal aberrations (OR = 0.75, 95%CI [0.31,1.77]), and hyperandrogenism (MD = 0.10, 95% CI [- 0.02, 0.22]) were not associated with the high spontaneous abortion rate in patients with PCOS. A subgroup analysis of BMI showed that there was no statistically significant difference in the effect between overweight and obesity on spontaneous abortion in PCOS patients undergoing ART (OR = 1.34, 95% [0.97, 1.85]). Conclusion High BMI and insulin resistance are two risk factors for an increased risk of spontaneous abortion in PCOS patients undergoing ART, and losing weight and mitigating insulin resistance may decrease the spontaneous abortion rate in these patients undergoing ART." @default.
• W3109958166 created "2020-12-07" @default.
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• W3109958166 date "2020-12-03" @default.
• W3109958166 modified "2023-10-13" @default.
• W3109958166 title "High BMI and Insulin Resistance Are Risk Factors for Spontaneous Abortion in Patients With Polycystic Ovary Syndrome Undergoing Assisted Reproductive Treatment: A Systematic Review and Meta-Analysis" @default.
• W3109958166 cites W1571332341 @default.
• W3109958166 cites W1759194051 @default.
• W3109958166 cites W1973768574 @default.
• W3109958166 cites W1977028559 @default.
• W3109958166 cites W1979143098 @default.
• W3109958166 cites W1981052608 @default.
• W3109958166 cites W1981855066 @default.
• W3109958166 cites W1988426085 @default.
• W3109958166 cites W1989901309 @default.
• W3109958166 cites W2019292337 @default.
• W3109958166 cites W2019301183 @default.
• W3109958166 cites W2020311655 @default.
• W3109958166 cites W2030795765 @default.
• W3109958166 cites W2031482067 @default.
• W3109958166 cites W2033129759 @default.
• W3109958166 cites W2037583931 @default.
• W3109958166 cites W2062436615 @default.
• W3109958166 cites W2073312761 @default.
• W3109958166 cites W2083685931 @default.
• W3109958166 cites W2086071784 @default.
• W3109958166 cites W2087974951 @default.
• W3109958166 cites W2088185348 @default.
• W3109958166 cites W2103966730 @default.
• W3109958166 cites W2105114771 @default.
• W3109958166 cites W2106838056 @default.
• W3109958166 cites W2108512287 @default.
• W3109958166 cites W2113068058 @default.
• W3109958166 cites W2113943040 @default.
• W3109958166 cites W2114781862 @default.
• W3109958166 cites W2120973019 @default.
• W3109958166 cites W2121615238 @default.
• W3109958166 cites W2124509857 @default.
• W3109958166 cites W2124760769 @default.
• W3109958166 cites W2126438731 @default.
• W3109958166 cites W2131192218 @default.
• W3109958166 cites W2133883611 @default.
• W3109958166 cites W2136927815 @default.
• W3109958166 cites W2141842430 @default.
• W3109958166 cites W2146737098 @default.
• W3109958166 cites W2149340887 @default.
• W3109958166 cites W2149505998 @default.
• W3109958166 cites W2153120485 @default.
• W3109958166 cites W2158675392 @default.
• W3109958166 cites W2164502461 @default.
• W3109958166 cites W2165753825 @default.
• W3109958166 cites W2167571203 @default.
• W3109958166 cites W2167867135 @default.
• W3109958166 cites W2170436191 @default.
• W3109958166 cites W2170468099 @default.
• W3109958166 cites W2186086116 @default.
• W3109958166 cites W2186218348 @default.
• W3109958166 cites W2296831586 @default.
• W3109958166 cites W2330499882 @default.
• W3109958166 cites W2336260784 @default.
• W3109958166 cites W2468996569 @default.
• W3109958166 cites W2523733243 @default.
• W3109958166 cites W2531203159 @default.
• W3109958166 cites W2546460045 @default.
• W3109958166 cites W2548439163 @default.
• W3109958166 cites W2561609317 @default.
• W3109958166 cites W2579378686 @default.
• W3109958166 cites W2580287388 @default.
• W3109958166 cites W2608729012 @default.
• W3109958166 cites W2737918278 @default.
• W3109958166 cites W2740355033 @default.
• W3109958166 cites W2741632770 @default.
• W3109958166 cites W2755850037 @default.
• W3109958166 cites W2792884650 @default.
• W3109958166 cites W2800808585 @default.
• W3109958166 cites W2808864885 @default.
• W3109958166 cites W2885317077 @default.
• W3109958166 cites W2895111545 @default.
• W3109958166 cites W2900886341 @default.
• W3109958166 cites W2911959152 @default.
• W3109958166 cites W2924564192 @default.
• W3109958166 cites W2951179714 @default.
• W3109958166 cites W2952817456 @default.
• W3109958166 cites W2957616322 @default.
• W3109958166 cites W2960334167 @default.
• W3109958166 cites W2977118001 @default.
• W3109958166 cites W2991755894 @default.
• W3109958166 cites W2995555212 @default.
• W3109958166 cites W2995769507 @default.
• W3109958166 cites W3000370624 @default.
• W3109958166 cites W3024973677 @default.
• W3109958166 doi "https://doi.org/10.3389/fendo.2020.592495" @default.
• W3109958166 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7744738" @default.
• W3109958166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33343510" @default.

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